| Sunday AM: Genetic/broad scale approaches to regulation |
| 9:30 - 9:45 AM | Meeting introduction and Session introduction, Rick Young |
| 9:45 - 10:10 | Rick Young - Global gene regulation in yeast |
| 10:15 - 10:40 | Mike Snyder - Global Analysis of the Yeast Genome |
| 10:45 - 11:15 | Break |
| 11:15 - 11:40 | Kevin Struhl - Molecular mechanisms of transcriptional
regulation in yeast |
| 11:45 - 12:15 | Geeta Narlikar - Dissecting the mechanism of ATP-dependent
chromatin remodeling |
| 12:30 | Lunch |
| 4:30 | Poster session I |
| Sunday PM: Chromosome dynamics |
| 7:30 - 7:40 | Session introduction, |
| 7:40 - 8:05 | Titia DeLange - "Protection and maintenance of human telomeres." |
| 8:10 - 8:35 | Dale Dorsett - "The Drosophila Nipped-B protein is required
for mitotic sister chromatid cohesion and participates in activation by
remote enhancers in the cut and
Ubx genes" |
| 8:40 - 9:00 | Break |
| 9:00 - 9:25 | Phil Hieter - Determinants of kinetochore function |
| 9:30 - 9:55 | Peter Sorger - |
| Monday AM: Chromatin remodeling/modification |
| 9:00 - 9:10 | Session introduction, Craig Peterson |
| 9:10 - 9:35 | Craig Peterson - "Global role for chromatin remodeling enzymes in mitotic gene expression" |
| 9:40 - 10:05 | LeAnn Howe - "The ADA and NuA3 HAT complexes: Unique HATs with
overlapping functions" |
| 10:10 - 10:35 | Toshi Tsukiyama - "Repression of early meiotic genes by Isw2
chromatin remodeling complex" |
| 10:40 - 11:10 | Break |
| 11:10 - 11:35 | Alan Hinnebusch - Transcriptional activation by GCN4 requires
independent interactions with the SRB/mediator, SAGA, and SWI/SNF
coactivators |
| 11:40 - 12:05 | Sharon Roth - "Functions of histone acetylation in yeast and
mice" |
| Monday PM: Recombination and repair |
| 7:30 - 7:40 | Session introduction, Margie Oettinger |
| 7:40 - 8:05 | Margie Oettinger - "Regulating the first steps of V(D)J recombination" |
| 8:10 - 8:35 | Tania Baker - "Chaperone-catalyzed disassembly of recombination complexes: mechanism and regulation" |
| 8:40 - 9:00 | Break |
| 9:00 - 9:25 | Marty Gellert - "V(D)J recombination as an entry into studying
double-strand break repair and transposition" |
| 9:30 - 9:55 | Steve Jackson - "Molecular insights into DNA repair and DNA
damage signalling" |
| Tuesday AM: Cell cycle control |
| 9:00 - 9:10 | Session introduction, Angelika Amon |
| 9:10 - 9:35 | Angelika Amon - Regulation of mitotic exit in yeast |
| 9:40 - 10:05 | Ray Deshaies - proteolysis and cell cycle control |
| 10:10 - 10:35 | Adam Rudner - Cdc28 phosphorylates and activates the APC |
| 10:40 - 11:10 | Break |
| 11:10 - 11:35 | Ted Weinert - DNA damage checkpoints: Attractive Molecular
Hypotheses, Weird Genomic Instability |
| 11:40 - 12:05 | Joachim Li - "CDKs prevent re-initiation of DNA replication
by multiple
overlapping mechanisms." |
| Tuesday PM: DNA Replication |
| 7:30 - 7:40 | Session introduction, Steve Bell |
| 7:40 - 8:05 | Steve Bell - "Assembly of DNA Replication Machines." |
| 8:10 - 8:35 | John Diffley - "Coordinating the initiation and elongation phases of DNA replication in budding yeast" |
| 8:40 - 9:00 | Break |
| 9:00 - 9:25 | Susan Gerbi - In the beginning --- initiation of DNA replication at a metazoan origin |
| 9:30 - 9:55 | M.K. Raghuraman (Raghu) - The topography of chromosome
replication in yeast: a genomic view |
| Wednesday AM: Structure/Enzymology |
| 9:00 - 9:10 | Session introduction, Ronen Marmorstein |
| 9:10 - 9:35 | Ronen Marmorstein - "Structure and Mechanism of Histone
Acetylation by the P/CAF, GCN5 and ESA1 Transcriptional Coactivators" |
| 9:40 - 10:05 | Mair Churchill - "Protein-DNA interactions in chromatin" |
| 10:10 - 10:35 | Jennifer Doudna - "Structure and function of the signal recognition particle: a surprising role for RNA in protein targeting?" |
| 10:40 - 11:10 | Break |
| 11:10 - 11:35 | Bob Sauer - An Evolutionary Bridge to a New Protein Fold: One
Mutant Sequence - Two Interconverting Native Structures |
| 11:40 -12:05 | Dan Herschlag - "Following Biological Processes One Molecule
at a Time" |
| Wednesday PM: Transcriptional regulation - Activation/GTF interactions |
| 7:30 - 7:40 | Session introduction, Michael Carey |
| 7:40 - 8:05 | Michael Carey - Enhanceosome structure and recruitment of
co-activator
complexes in vitro |
| 8:10 - 8:35 | Joan Conaway - The VHL tumor suppressor complex and regulation
of hypoxia-inducible genes. |
| 8:40 - 9:00 | Break |
| 9:00 - 9:25 | Bob Roeder - "Role of the TRAP/Mediator Complex in Transcriptional
Regulation |
| 9:30 - 9:55 | Michael Green - "Mechanisms of Transcriptional Activation In
Vivo" |
| Thursday AM: Splicing/RNA Function |
| 9:30 - 9:40 | Session introduction, Melissa Moore |
| 9:40 - 10:05 | Melissa Moore - "A mark of distinction for spliced mRNAs" |
| 10:10 - 10:35 | Jamie Cate - "Ribosome Structure and Translational Accuracy." |
| 10:40 - 11:10 | Break |
| 11:10 - 11:35 | Adrian Krainer - Exon mutations that cause exon skipping:
mechanisms and implications |
| 11:40 - 12:05 | Jamie Williamson - "RNA-protein interactions in the
assembling ribosome" |
