Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Communication Between Organelles and with the Outside
7:40 pm - 8:20 pm
"Emerging Network of Membrane Contact Sites"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"RNA Sorting and Secretion in Exosomes"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Regulation of Biosynthesis and the Early Secretory Pathway
9:00 am - 9:20 am
"ABC Transporters Implicated in Biopolymer Translocation"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Mechanism of ER-Associated Protein Degradation (ERAD)"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Stress Sensing and Apoptotic Induction by Tubular ER Protein HT008"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Mechanical Force Induces Mitochondrial Fission via the Canonical Fission Machinery"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Targeting of Membrane Proteins from the ER to the Inner Nuclear Membrane"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Sec16: A Stress Response Protein"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Exploring and Exploiting Intracellular Transport of Mammalian Cells"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulation of Golgi Function and Transport
7:30 pm - 7:50 pm
"Know When to Hold 'Em, Know When to Fold 'Em: Chaperoning SNARE Assembly to Control Membrane Fusion"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Kinetic Mapping of Secretory and Endocytic Traffic in Yeast"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"4D Imaging of Cargo Delivery in Maturating Golgi Cisternae in S. cerevisiae "
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Golgins and Tethering of Vesicles at the Golgi Apparatus"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Molecular Function and Structural Features of Vps13 "
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Regulation of Exo- and Endocytosis
9:00 am - 9:20 am
"Molecular Mechanisms of Synaptic Vesicle Priming"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Regulation of Exocyst by Polarity Proteins"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Spectrin, a Dynamic Mechanosensory Protein that Promotes Cell Membrane Fusion"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Membrane Trafficking Proteins Important for Dense-Core-Vesicle Maturation"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Reconstitution of Endosomal Rab Delivery and Activation"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Emerging New Roles of Lysosomes in Cellular Homeostasis"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Epithelial-Stromal Crosstalk in Tube Development"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Communication in Disease,
Infection and Immune Response
7:30 pm - 7:50 pm
"Haploid Genetic Screens to Study Pathogen Entry"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Fine-Tuning Lysosomal Secretion"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Forward Genetic Screens to Identify Novel Ubiquitin E3 Ligases in the Secretory Pathway"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Chlamydia Hijacks ARF GTPases to Coordinate Microtubule Post-Translational Modifications and Golgi Positioning"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"A Rab32 Trafficking Pathway that Prevents Bacterial Infections"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Alternative Ways of
Communication
9:00 am - 9:20 am
"Mechanisms of Lipid Homeostasis in the Endoplasmic Reticulum"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Molecular Determinants of a Lipid Droplet Subpopulation at the Nucleus-Vacuole Junction"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Versatile Functions of Syntaxin 17 in the ER-Mitochondria Contact Site"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Nutrient-Regulated Destruction of Mitochondrial Metabolite Carriers by the MDC Pathway"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Molecular Mechanisms of Biogenesis and Secretion of Exosomes and Other Extracellular Vesicles"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Differential Identity of Tunneling Nanotube and Filopodia and Revealed by the Opposite Functions of Actin Regulatory Complexes and Ultrastructural Analysis"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"T Cell Receptor Clustering – A Mechanism of Signal Transduction"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Regulation of Transport by Lipids
7:30 pm - 7:50 pm
"Phosphatidylinositol 4-Phosphate Gradients Shape the Lipid Landscape of Eukaryotic Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Lipid Trafficking and Storage in the ER"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Cholesterol Regulation of Lysosomes"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Cargo Sorting During Protein Secretion"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Sphingomyelin-Dependent Sorting and Trafficking in the Secretory Pathway"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Regulation of Degradation
Pathways and Signalling
9:00 am - 9:20 am
"ESCRTs and Ubiquitin Function in Lysosomal Membrane Protein Turnover and Quality Control"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Dynamic Regulation of the Endosomal Lipid PI(3,5)P2"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Trafficking to the Forming Autophagosome"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"Triggered Recruitment of ESCRT Machinery Facilitates Endolysosomal Membrane Repair"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"GRASP55 Senses Energy Deprivation Through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Crucial Role of an Inner Mitochondrial Membrane Receptor in Mitophagy"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Regulation and Roles of Autophagy in the Mammalian Brain"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
New
Frontiers in Molecular Membrane Biology
7:30 pm - 7:50 pm
"Mitochondrial Vesicles in Antigen Presentation: A New Paradigm for Parkinson's Disease?"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Mitochondrial-Driven Assembly of a Cortical Anchor for Mitochondria and Dynein"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"'GFP-Omics': Endogenous GFP-Tagging of the Human Proteome"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Systematic Exploration of Endocytosis and Phagocytosis Pathways Using Genome-Wide CRISPR/Cas9 Screens and Genetic Interaction Maps"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Cellular Imaging from Molecules to Organisms"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure