Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Cytoskeletal Structure and Function
Discussion Leader: Sandra Lemke (Max Planck Institute of Biochemistry, Germany)
3:45 pm - 4:00 pm
Amy Byrnes (University of North Carolina at Chapel Hill, USA)
"Polarized TOG-Tubulin Binding Specificity Regulates Microtubule Polymerization and Mitotic Spindle Formation"
4:00 pm - 4:05 pm
Discussion
4:05 pm - 4:20 pm
Guillaume Duclos (Brandeis Univiersity, USA)
"Instability in an Active Nematic Composed of Microtubules and Kinesin-1 Motors"
4:20 pm - 4:25 pm
Discussion
4:25 pm - 4:30 pm
General Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Dynamic Cytoskeletal Regulation and Associated Proteins
Discussion Leader: Guillaume Duclos (Brandeis Univiersity, USA)
7:30 pm - 7:45 pm
Maya Malik Garbi (Technion - Israel Institute of Technology, Israel)
"Quantitative Analysis of Actin Network Contraction and Turnover in Cell-Sized Droplets"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Rachel Kadzik (Princeton University, USA)
"XMAP215 Is a Microtubule Nucleation Factor that Functions Synergistically with the γ-Tubulin Ring Complex"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Torey Arnold (University of Michigan, USA)
"Anillin Regulates Epithelial Cell Mechanics by Structuring the Medial-Apical Actin Network"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Lindsay Case (University of Texas Southwestern Medical Center, USA)
"Phase Separation Enhances Arp2/3 Complex-Dependent Actin Polymerization by Increasing the Membrane Dwell Time of N-WASP"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Nida Siddiqui (Centre for Mechanochemical Cell Biology, University of Warwick, United Kingdom)
"Kinesin Control of Cell Adhesion Structures"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Kriti Sethi (Mechanobiology Institute, National University of Singapore, Singapore)
"RHO-1 GEFs RHGF-1 and UNC-73 Promote Actomyosin Contractility in C. elegans Spermatheca"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Cells, Tissues, and Organisms
Discussion Leader: Alison Wirshing (Northeastern University, USA)
9:00 am - 9:15 am
Brian Graziano (University of California, San Francisco, USA)
"Proper Actin Network Architecture Is Essential for Restricting Polarization to a Single Leading Edge in Neutrophils"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Sandra Lemke (Max Planck Institute of Biochemistry, Germany)
"Measuring Molecular Tension During Myofibril Assembly"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Hannah Yevick (Massachusetts Institute of Technology, USA)
"Diverse Supracellular Actomyosin Connectivity Yields Robust Tissue Folding"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Aaron Van Loon (University of California, Los Angeles, USA)
"Contractile Forces Shape the Labyrinthine Surface of Mucosal Epithelial Cells"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Jennifer Landino (Vanderbilt University, USA)
"Actin-Based Recruitment of the Chromosomal Passenger Complex to the Division Site During Cytokinesis"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Alexander Mietke (Max Planck Institute for the Physics of Complex Systems, Germany)
"Emergent Cell and Tissue Shape: Active Matter in Complex and Deforming Geometries"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Navigating Scientific Careers Outside of Academia
Discussion Leader: Hannah Yevick (Massachusetts Institute of Technology, USA)
1:30 pm - 2:30 pm
Panel Discussion
Non-Traditional Career Paths for Graduate Students and Postdocs with a Background in Cytoskeletal Research
Michelle Avery (Summit Therapeutics, USA)
Nicole Neuman (Trends in Biochemical Sciences, Cell Press, USA)
Denise Zannino (AAAS Science and Technology Policy Fellow, National Science Foundation, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes