Saturday 
 
 
1:30 pm - 4:30 pm 
	
Arrival and Check-in
 
 
						
3:00 pm - 3:15 pm 
	
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
 
 
						
3:15 pm - 4:00 pm 
	
In Silico  Approaches and Methods in Structural Biology 
 
 
						
3:15 pm - 3:25 pm 
	
"Toward Synthetic Membranes: Functional Reconstitution of Two ABC Exporters in Hybrid Lipid-Polymer Vesicles" 
 
 
 
						
3:25 pm - 3:30 pm 
	
Discussion
 
 
						
3:30 pm - 3:40 pm 
	
"Functional Difference Between MexXY-OprM and MexXY-OprA RND Efflux Systems in Pseudomonas aeruginosa " 
 
 
 
						
3:40 pm - 3:45 pm 
	
Discussion
 
 
						
3:45 pm - 3:55 pm 
	
"Arylhydrocarbon Receptor-Mediated Signaling of ABC Transporters and Solute Carriers in Human Renal Proximal Epithelial Tubular Cells and Proximal Renal Tubules from Killifish" 
 
 
 
						
3:55 pm - 4:00 pm 
	
Discussion
 
 
						
4:00 pm - 5:30 pm 
	
Poster Session 
 
 
						
5:30 pm - 7:30 pm 
	
Molecular Mechanisms Driving to Multi-Drug Efflux of Antibiotics or Anti-Cancer Drugs 
 
 
 
						
5:30 pm - 5:45 pm 
	
"Characterization and Regulation of a Novel Efflux Pump from the Major Facilitator Superfamily in Streptomyces coelicolor  M145" 
 
 
 
						
5:45 pm - 5:50 pm 
	
Discussion
 
 
						
5:50 pm - 6:05 pm 
	
"Drug Resistant Cancer Cells Can Be Targeted by Oridonin" 
 
 
 
						
6:05 pm - 6:10 pm 
	
Discussion
 
 
						
6:10 pm - 6:25 pm 
	
"Susceptibility of Pseudomonas aeruginosa  to Antibiotics Can Be Compromised by Essential Oils" 
 
 
 
						
6:25 pm - 6:30 pm 
	
Discussion
 
 
						
6:30 pm - 6:45 pm 
	
"ATP-Dependent Substrate Transport by the ABC Transporter MsbA Is Proton-Coupled" 
 
 
 
						
6:45 pm - 6:50 pm 
	
Discussion
 
 
						
6:50 pm - 7:05 pm 
	
"Single Amino Acid Changes in MtrD Impact Susceptibility of Neisseria gonorrhoeae  to Macrolides" 
 
 
 
						
7:05 pm - 7:10 pm 
	
Discussion
 
 
						
7:10 pm - 7:25 pm 
	
"TtgABC and a Novel RND Efflux Pump ParXY Are Co-Regulated by a Two-Component System in Pseudomonas putida " 
 
 
 
						
7:25 pm - 7:30 pm 
	
Discussion
 
 
						
8:00 pm - 9:00 pm 
	
Dinner
 
 
						
	Sunday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 11:00 am 
	
Keynote Session: Physiological Role of Efflux Systems / Insights into Drug Discovery and Development 
 
 
 
						
9:00 am - 9:20 am 
	
"A Battle of the Titans: Strategies to Fight Multidrug Resistance in Cancer" 
 
 
 
						
9:20 am - 9:25 am 
	
Discussion
 
 
						
9:25 am - 9:35 am 
	
"Molecular Mechanism Underlying P-Glycoprotein Efflux of Anthracycline Drugs" 
 
 
 
						
9:35 am - 9:40 am 
	
Discussion
 
 
						
9:40 am - 9:50 am 
	
"Discovery of New Efflux Pump Inhibitors that Interact with AcrA of the Escherichia coli  AcrAB-TolC Efflux Pump" 
 
 
 
						
9:50 am - 9:55 am 
	
Discussion
 
 
						
9:55 am - 10:05 am 
	
"Substrates of the Anaerobic Efflux Pump MdtEF-TolC" 
 
 
 
						
10:05 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:20 am 
	
"Investigating the Regulatory Circuits Controlling Multidrug Efflux Pump Expression in Acinetobacter baumannii " 
 
 
 
						
10:20 am - 10:25 am 
	
Discussion
 
 
						
10:25 am - 10:35 am 
	
"Reconstitution of the Activity of Efflux Pump into Proteoliposomes" 
 
 
 
						
10:35 am - 10:40 am 
	
Discussion
 
 
						
10:40 am - 10:50 am 
	
"Towards Single-Molecule Characterization of the Alternating Access Mechanism in MdfA" 
 
 
 
						
10:50 am - 10:55 am 
	
Discussion
 
 
						
10:55 am - 11:00 am 
	
General Discussion
 
 
						
11:00 am - 12:30 pm 
	
Poster Session 
Coffee will be served in the poster area from 11:00 am - 11:30 am 
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 2:30 pm 
	
Mentorship Component: Scientific Networking and Grant Writing 
 
 
 
						
1:30 pm - 2:30 pm 
	
Panel Discussion 
Scientific Networking and Grant Writing 
 
 
 
						
2:30 pm - 3:00 pm 
	
Evaluation Period 
Fill in GRS Evaluation Forms 
 
 
						
3:00 pm 
	
Seminar Concludes