| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in / Posters go up |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Keynote Lecture |
| Welcome: B. Zalc (INSERM U495, Paris) |
| Introduction: Robert H. Miller (Case Western Reserve University, Cleveland) |
| Nicole LeDouarin (Academie des Sciences, Paris)
"The neural crest: a pluripotent structure of the Vertebrate embryo" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Membrane and myelin structure |
| Discussion leaders: David Colman (The Montreal Neurological Institute) & Anthony Campagnoni (UCLA Medical School, Los Angeles) |
| 9:00 am - 9:15 am | Introductory remarks: David Colman |
| 9:15 am - 9:45 am | Bob Gould (University of Illinois, Chicago)
"Myelination did not begin nor will it end with furry creatures" |
| 9:45 am - 10:15 am | Jacqueline Trotter (University of Mainz)
"Oligodendroglial membrane dynamics in progenitor cells and myelinating oligodendrocytes" |
| 10:15 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Conference Photo |
| 11:30 am - 12:00 pm | Steve Pfeiffer (University of Connecticut Medical School, Farmington)
"The Myelin-Axolemmal Complex: Proteomic Analysis of Signal Transduction Mediated by Lipid Rafts" |
| 12:00 pm - 12:30 pm | Nicole Schaeren-Wiemers (University Hospital Basel)
"The raft-associated protein MAL is required for maintenance of proper axon-glia interactions in the central nervous system" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Informal afternoon discussions |
| 4:00 pm - 5:00 pm | Poster Session |
| 5:20 pm - 7:30 pm | Multiple Sclerosis |
| Discussion leader: Catherine Lubetzki (INSERM U495, Paris) |
| 5:20 pm - 5:30 pm | Introductory remarks: Catherine Lubetzki |
| 5:30 pm - 6:00 pm | Cedric Raine (Albert Einstein College orf Medicine, Bronx)
"Receptor crosstalk between oligodendrocytes and other glial cells: Relevance to multiple sclerosis" |
| 6:00 pm - 6:30 pm | Claudia Luchinetti (Mayo Clinic, Rochester)
"Pathologic Heterogeneity in Multiple Sclerosis: Pathogenic and Clinical Implications" |
| 6:30 pm - 7:00 pm | Alastair Compston (University of Cambridge Clinical School, Cambridge)
"Genetic analysis of multiple sclerosis" |
| 7:00 pm - 7:30 pm | Massimo Filippi (Scientific Institute Hop San Raffaele, Milano)
"Mechanisms of disability accumulation in MS studied using MR-based techniques" |
| 8:00 pm | Dinner |
| 9:00 pm | Poster Session |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Animal models of demyelination |
| Discussion leaders: Sam Ludwin (Queens University, Kingston) & Anne Baron van Evercooren (INSERM U546, Paris) |
| 9:00 am - 9:10 am | Introductory remarks: Sam Ludwin |
| 9:10 am - 9:50 am | Klaus Nave (Max-Planck-Institute of Experimental Medicine, Göttingen)
"Conditional mouse mutants lacking cholesterolbiosynthesis" |
| 9:50 am - 10:30 am | Brian Popko (University of Chicago, Chicago)
"Interferon gamma's effects on oligodendrocytes: a Delphian sword?" |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Richard Ransohoff (Cleveland Clinic Foundation, Cleveland)
"Control of microglial activation by chemokines and chemokine receptors" |
| 11:30 am - 12:00 pm | Steve Levison (Penn State College of Medicine, Hershey)
"Progenitor Cell Loss as a Component of Perinatal White Matter Damage" |
| 12:00 pm - 12:30 pm | Emiliana Borelli (Institut de Genetique et Biologie Moleculaire, Strasbourg)
"An inducible cell ablation system to analyze oligodendrocyte function in vivo" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Informal afternoon discussions |
| 4:00 pm - 5:00 pm | Poster Session |
| 5:20 pm - 7:30 pm | Subspecialization of myelin |
| Discussion leaders: Elior Peles (Weizmann Institute of Science, Rehovot) |
| 5:20 pm - 5:30 pm | Introductory remarks: Elior Peles |
| 5:30 pm - 6:00 pm | Jean Antoine Girault (INSERM U536, Paris)
"A role for schwannomin in the organization of nodal regions in the peripheral nervous system" |
| 6:00 pm - 6:30 pm | Matthew Rasband (University of Connecticut Health Center, Farmington) |
| 6:30 pm - 7:00 pm | Peter Brophy (University of Edinburgh)
"Glial contributions to axon-glial interaction" |
| 7:00 pm - 7:30 pm | Bettina Winckler (Mount Sinai School of Medicine, New York)
"Keeping proteins in check: Diffusion barriers in the axonal initial segment" |
| 8:00 pm | Dinner |
| 9:00 pm | Poster Session |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Molecular control of migration of myelin forming cells |
| Discussion leaders: Jim Goldman (Columbia University, New York)
& Tim Kennedy (Montreal Neurological Institute) |
| 9:00 am - 9:10 am | Introductory remarks: Jim Goldman |
| 9:10 am - 9:50 am | Salvador Martinez (CSIC-UMH, Alicante)
"Mapping the pathways of migration of oligodendrocyte in the brain" |
| 9:50 am - 10:30 am | Nobuaki Tamamaki (Kyoto University)
"Heterogeneity found in the oligodendrocyte precursor cells in the murine optic nerve" |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Jean Leon Thomas (INSERM U495, Paris)
"Entering the optic nerve: molecular cues for OPCs" |
| 11:30 am - 12:00 pm | Hui-Hsin Tsai (Case Western Reserve University, Cleveland)
"Mechanisms of oligodendrocyte precursor migration in the spinal cord" |
| 12:00 pm - 12:30 pm | Maria Elena de Bellard (Caltech, Los Angeles)
"Dual function of Slit as chemorepulsive and chemotactic molecule on neural crest cells" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Informal afternoon discussions during excursion to Lucca |
| 4:00 pm - 5:00 pm | Poster Session |
| 5:20 pm - 7:30 pm | Oligodendroglioma and Schwannoma |
| Discussion leader: Ueli Suter (ETH, Zürich) |
| 5:20 pm - 5:30 pm | Introductory remarks: Ueli Suter |
| 5:30 pm - 6:00 pm | David Rowitch (Dana-Farber Cancer Institute, Cambridge USA)
"Olig Function In CNS Development and Tumorigenesis" |
| 6:00 pm - 6:30 pm | Eric Holland (Memorial Sloan-Kettering, New York)
"Maintenance of the oligodendroglioma neoplastic phenotype" |
| 6:30 pm - 7:00 pm | Bill Weiss (UCSF, San Francisco)
"S100b, stem cells, and mouse models for oligodendroglioma" |
| 7:00 pm - 7:30 pm | Luis Parada (University of Texas, Dallas)
"Modeling Neurofibromatosis in the Mouse" |
| 8:00 pm | Dinner |
| 9:00 pm | Poster Session |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Signaling to and by myelin forming cells |
| Discussion leaders: Marie Filbin (Hunter College, New York)
& Douglas Fields (National Institutes of Health, Bethesda) |
| 9:00 am - 9:10 am | Introductory remarks: Marie Filbin |
| 9:10 am - 9:50 am | Charles Ffrench-Constant (University of Cambridge, UK)
"Regulation of growth factor signalling by integrins" |
| 9:50 am - 10:30 am | Carmen Birchmeier (Max-Delbrück-Centrum, Berlin)
"The function of the Neuregulin/ErbB signalling system in development of the nervous system" |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Terri Wood (Penn State University, Hershey)
"Convergence of Signaling Pathways on Cell Cycle Targets in Oligodendrocyte Progenitors" |
| 11:30 am - 12:00 pm | Rashmi Bansal (University of Connecticut Medical School, Farmington)
"FGF receptor signaling in the regulation of oligodendrocyte differentiation" |
| 12:00 pm - 12:30 pm | Kaz Ikenaka (National Institute for Physiological Science, Okazaki)
"Abnormal signaling in a very early stage and a chronic demyelinating stage during demyelination" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Informal afternoon discussions |
| 4:00 pm - 5:00 pm | Business Meeting |
| 5:20 pm - 7:30 pm | Regeneration |
| Discussion leaders: Monique Dubois-Dalcq (Institut Pasteur, Paris)
& Richard Reynolds (Imperial College London) |
| 5:20 pm - 5:30 pm | Introductory remarks: Monique Dubois-Dalcq |
| 5:30 pm - 6:00 pm | Jean Merrill (Aventis Pharmaceuticals, Bridgewater)
"Oligodendrocyte Protection and Differentiation as Therapeutic Approaches for Treating MS" |
| 6:00 pm - 6:30 pm | Gianvitto Martino (San Raffaele Scientific Institute, Milano)
"Neuroprotection in multiple sclerosis: the role of neural stem cells" |
| 6:30 pm - 7:00 pm | Robin Franklin (University of Cambridge, UK)
"Mechanisms of CNS remyelination" |
| 7:00 pm - 7:30 pm | Frank Walsh (Wyeth Research, Princeton)
"New drug discovery opportunities for regeneration" |
| 8:00 pm | Conference Banquet & Farewell Party |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
