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Myogenesis

Gordon Research Conference

Mechanisms of Myogenesis in Development, Health, and Disease

June 8 - 13, 2025

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GRC Education Requirements: Undergraduates or those who have not obtained a bachelor's degree in science/engineering (or acceptable equivalent) are not eligible to apply to attend Gordon Research Conferences or Seminars.

Chairs

and

Vice Chairs

and

Renaissance Tuscany Il Ciocco

Via Giovanni Pascoli

Lucca (Barga), Lucca, Italy

Venue and Travel Information

Application Information

The application deadline for this meeting was May 11, 2025. You may still submit an application, which may be considered by the conference chair if there is still room available.

Conference Description

The Myogenesis GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes an array of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Related Meeting

This GRC will be held in conjunction with the "Myogenesis" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Keynote Session: Perspectives on Myogenesis Discussion Leader:
7:40 pm - 7:55 pm	Introduction by Discussion Leader
7:55 pm - 8:10 pm	Talk Selected from GRS
8:10 pm - 8:20 pm	Discussion
8:20 pm - 9:05 pm	"Muscular Genomes"
9:05 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Aging in Muscle Health and Disease Discussion Leader:
9:00 am - 9:20 am	"Epigenetic Clocks Applied to Muscle Tissue"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Aging Mechanisms that Perturb Skeletal Muscle Size and Function"
9:50 am - 10:00 am	Discussion
10:00 am - 10:10 am	"Sexually Dimorphic Hormonal Regulation of Skeletal Muscle Regenerative Potential and its Loss/Restoration with Age"
10:10 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:05 am	"Mechanisms of Muscle Wasting in Cachexia and Aging"
11:05 am - 11:15 am	Discussion
11:15 am - 11:35 am	"Brain-Muscle Crosstalk in Physiology and Aging"
11:35 am - 11:45 am	Discussion
11:45 am - 12:05 pm	"Geriatric Mice Cannot Regrow Muscle After Immobilisation Due to Altered Transcriptional Activity"
12:05 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Epigenetic Regulation of Myogenesis Discussion Leader:
6:00 pm - 6:20 pm	"Chromatin-Nuclear Lamina Interactions Regulate Fibro-Adipogenic Progenitors Identity"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:40 pm	"Skeletal Muscle Cell Identity is Preserved by H3.3 Histone Chaperones"
6:40 pm - 6:45 pm	Discussion
6:45 pm - 7:05 pm	"Epigenetic Integration of Signaling from the Regenerative Niche"
7:05 pm - 7:15 pm	Discussion
7:15 pm - 7:25 pm	"Neural Crest-Derived Fibro-Adipogenic Progenitors Regulate Orofacial Muscle Fibrosis via Foxo1/PP2A/Mstn"
7:25 pm - 7:30 pm	Discussion
7:30 pm - 7:50 pm	"Epigenetic Control of Gene Expression in Skeletal Muscle During Physiological and Pathological Perturbations"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Tuesday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	The Muscle Stem Cell Niche Discussion Leader:
9:00 am - 9:20 am	"Niche Regulation of Muscle Stem Cell Quiescence"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"The Regenerative Niche in Normal and Pathological Muscle"
9:50 am - 10:00 am	Discussion
10:00 am - 10:10 am	"Spatiotemporal Dynamics of Polyamine Metabolism in Skeletal Muscle: Implications for Muscle Homeostasis and Pathophysiology"
10:10 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:05 am	"Novel Roles of the Extracellular Matrix in the Skeletal Muscle Stem Cell Niche"
11:05 am - 11:15 am	Discussion
11:15 am - 11:35 am	"Biophysical Regulation of Muscle Stem Cell Fate"
11:35 am - 11:45 am	Discussion
11:45 am - 11:55 am	"Deciphering the Fibroadipogenic Progenitor Interactome: A Systems Approach to Their Role in Muscle Regeneration"
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	,,, "Distinct Regenerative Properties of Extra-Ocular Muscle FAPs Support Muscle Stem Cell Maintenance"
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Muscle Diseases and Therapies Discussion Leader:
6:00 pm - 6:20 pm	"Assessing Satellite Cell Dysfunction in the Cause and Progression of Muscular Dystrophies"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Zebrafish Models of Dystroglycanopathies Provide New Insight into Neuromuscular Development"
6:50 pm - 7:00 pm	Discussion
7:00 pm - 7:20 pm	"Muscle Regeneration Following Viral Infection"
7:20 pm - 7:30 pm	Discussion
7:30 pm - 7:50 pm	"Limb Muscle Regeneration in Peripheral Artery Disease"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Innovations in Muscle Research Discussion Leader:
9:00 am - 9:20 am	"Biomaterials as Drugs to Regenerate Skeletal Muscle"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Linking Hematopoietic and Neuromuscular Aging at Single Cell Resolution"
9:50 am - 10:00 am	Discussion
10:00 am - 10:10 am	"Towards Myonuclear Subtype Specific Genetics"
10:10 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:05 am	"Maintenance and Regulation of Muscle Fibre Junctions in Humans"
11:05 am - 11:15 am	Discussion
11:15 am - 11:35 am	"RNA Binding Proteins Orchestrate Myogenesis"
11:35 am - 11:45 am	Discussion
11:45 am - 11:55 am	"Controlling Skeletal Muscle Activation in vivo Using Optogenetics"
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	"Repairing Skeletal Muscle Without Stem Cells"
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Development of Muscle and Associated Tissues Discussion Leader:
6:00 pm - 6:20 pm	"Distinct Morphogenetic Events and Signaling Pathways Regulate the Formation and Deployment of Muscle Stem Cell Populations During Growth and Regeneration"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:40 pm	"Molecular and Mechanical Drivers of Fibroblast Identity During Limb Development"
6:40 pm - 6:45 pm	Discussion
6:45 pm - 7:05 pm	"Regulation of Muscle Stem Cell Fate by p53"
7:05 pm - 7:15 pm	Discussion
7:15 pm - 7:25 pm	"Blueprinting Muscle Heterogeneity Along the Body Axis"
7:25 pm - 7:30 pm	Discussion
7:30 pm - 7:50 pm	"The Lifecycle of Proprioception: Insights into Muscle Spindle Development and Aging"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Regulation of Gene Expression in Muscle Discussion Leader:
9:00 am - 9:20 am	"Coordinating Transcriptional Control and Intracellular Remodeling During Adult Myogenesis"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"A CTCF Dependent Code for Migratory Myogenic Progenitors"
9:50 am - 10:00 am	Discussion
10:00 am - 10:10 am	"Multiple Isoforms of the CELF Homolog Bruno1 are Required for Flight Muscle Development in Drosophila"
10:10 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:05 am	"DNA G-Quadruplexes(G4s) Profiling Reveals Functional and Mechanistic Role of G4s in Skeletal Muscle Stem Cells"
11:05 am - 11:15 am	Discussion
11:15 am - 11:35 am	"Molecular Regulation of Muscle Stem Cell Function"
11:35 am - 11:45 am	Discussion
11:45 am - 11:55 am	"How to Divide a Multinucleated Cell – Lessons from Myofiber Splitting of Drosophila Indirect Flight Muscles"
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	"Odd-skipped Related 1 is Required for the Myogenic-to-Brown Adipogenic Switch and Defines a New Source for Brown Adipose Tissue"
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Physiological Regulation of Myogenesis Discussion Leader:
6:00 pm - 6:20 pm	"Muscle Circadian Clock as a Transcriptional Hub for Homeostasis and Adaptation"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Regulatory Mechanisms of FAP in Modulating MuSC Dynamics during Regeneration and Hypertrophy"
6:50 pm - 7:00 pm	Discussion
7:00 pm - 7:20 pm	"Menopause Compromises Skeletal Muscle Quality and Function Through Dysregulation of Fibro-Adipogenic Progenitors"
7:20 pm - 7:30 pm	Discussion
7:30 pm - 7:50 pm	"Tuning Myofiber Identity Switch to Alleviate Dietary Obesity"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Research reported in this publication was supported by the National Institute On Aging, National Institute Of Environmental Health Sciences, National Institute Of Neurological Disorders And Stroke, and the National Cancer Institute of the National Institutes of Health under Award Number 1R13AR085495-01. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

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Conference Fees

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

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Funding Opportunities

Financial assistance is available beginning in 2026 for qualified applicants through the Carl Storm Opportunity Fellowships program. Learn more.

Registration Fees

Conferee Single Room:

$1,610.00

Conferee Shared Room:

$1,325.00

Conferee Off-Site:

$915.00

Guest Single Room:

$1,420.00

Guest Shared Room:

$1,135.00

Guest Off-Site:

$725.00

Child 4-12 yrs Shared Room:

$568.00

Child 4-12 yrs Off-Site:

$363.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Bus Arriving:

$62.00

Bus Departing:

$62.00

Additional Fee Info

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