Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Perspectives on Myogenesis
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:10 pm
Talk Selected from GRS
8:10 pm - 8:20 pm
Discussion
8:20 pm - 9:05 pm
9:05 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Aging in Muscle Health and Disease
9:00 am - 9:20 am
"Epigenetic Clocks Applied to Muscle Tissue"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Aging Mechanisms that Perturb Skeletal Muscle Size and Function"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Sexually Dimorphic Hormonal Regulation of Skeletal Muscle Regenerative Potential and its Loss/Restoration with Age"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Brain-Muscle Crosstalk in Physiology and Aging"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Geriatric Mice Cannot Regrow Muscle After Immobilisation Due to Altered Transcriptional Activity"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Menopause Compromises Skeletal Muscle Quality and Function Through Dysregulation of Fibro-Adipogenic Progenitors"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Epigenetic Regulation of Myogenesis
6:00 pm - 6:20 pm
"Chromatin-Nuclear Lamina Interactions Regulate Fibro-Adipogenic Progenitors Identity"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Skeletal Muscle Cell Identity is Preserved by H3.3 Histone Chaperones"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Epigenetic Integration of Signaling from the Regenerative Niche"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Neural Crest-Derived Fibro-Adipogenic Progenitor Cells Regulate Orofacial Muscle Fibrosis via Foxo1/PP2A/Mstn"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Epigenetic Control of Gene Expression in Skeletal Muscle During Physiological and Pathological Perturbations"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
The Muscle Stem Cell Niche
9:00 am - 9:20 am
"Niche Regulation of Muscle Stem Cell Quiescence"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"The Regenerative Niche in Normal and Pathological Muscle"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Spatiotemporal Dynamics of Polyamine Metabolism in Skeletal Muscle: Implications for Muscle Homeostasis and Pathophysiology"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Novel Roles of the Extracellular Matrix in the Skeletal Muscle Stem Cell Niche"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Biophysical Regulation of Muscle Stem Cell Fate"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Deciphering the Fibroadipogenic Progenitor Interactome: A Systems Approach to Their Role in Muscle Regeneration"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Distinct Regenerative Properties of Extra-Ocular Muscle FAPs Support Muscle Stem Cell Maintenance"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Muscle Diseases and Therapies
6:00 pm - 6:20 pm
"Assessing Satellite Cell Dysfunction in the Cause and Progression of Muscular Dystrophies"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Zebrafish Models of Dystroglycanopathies Provide New Insight into Neuromuscular Development"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Muscle Regeneration Following Viral Infection"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Limb Muscle Regeneration in Peripheral Artery Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Innovations in Muscle Research
9:00 am - 9:20 am
"Biomaterials as Drugs to Regenerate Skeletal Muscle"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Linking Hematopoietic and Neuromuscular Aging at Single Cell Resolution"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Towards Myonuclear Subtype Specific Genetics"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Maintenance and Regulation of Muscle Fibre Junctions in Humans"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"RNA Binding Proteins Orchestrate Myogenesis"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Controlling Skeletal Muscle Activation in vivo Using Optogenetics"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Repairing Skeletal Muscle Without Stem Cells"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Development of Muscle and Associated Tissues
6:00 pm - 6:20 pm
"Distinct Morphogenetic Events and Signaling Pathways Regulate the Formation and Deployment of Muscle Stem Cell Populations During Growth and Regeneration"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Molecular and Mechanical Drivers of Fibroblast Identity During Limb Development"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Regulation of Muscle Stem Cell Fate by p53"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Blueprinting Muscle Heterogeneity Along the Body Axis"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"The Lifecycle of Proprioception: Insights into Muscle Spindle Development and Aging"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Regulation of Gene Expression in Muscle
9:00 am - 9:20 am
"Coordinating Transcriptional Control and Intracellular Remodeling During Adult Myogenesis"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"A CTCF Dependent Code for Migratory Myogenic Progenitors"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Multiple Isoforms of the CELF Homolog Bruno1 are Required for Flight Muscle Development in Drosophila "
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"DNA G-Quadruplexes(G4s) Profiling Reveals Functional and Mechanistic Role of G4s in Skeletal Muscle Stem Cells"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Molecular Regulation of Muscle Stem Cell Function"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"How to Divide a Multinucleated Cell – Lessons from Myofiber Splitting of Drosophila Indirect Flight Muscles"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Odd-skipped Related 1 is Required for the Myogenic-to-Brown Adipogenic Switch and Defines a New Source for Brown Adipose Tissue"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Physiological Regulation of Myogenesis
6:00 pm - 6:20 pm
"Muscle Circadian Clock as a Transcriptional Hub for Homeostasis and Adaptation"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Mechanisms of Muscle Wasting in Cachexia and Aging"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Regulatory Mechanisms of FAP in Modulating MuSC Dynamics during Regeneration and Hypertrophy"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Tuning Myofiber Identity Switch to Alleviate Dietary Obesity"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure