Sunday |
2:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Cancer: Viruses and Signaling |
| Discussion Leader: Alan Rickinson (University of Birmingham, United Kingdom) |
7:40 pm - 7:45 pm | Introduction by Discussion Leader |
7:45 pm - 8:25 pm | Harald zur Hausen (German Cancer Research Center, Germany) "Discovery and Early Studies of EBV in Burkitt's Lymphoma and NPC" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:20 pm | Hans Clevers (Hubrecht Institute, The Netherlands) "Wnt Signaling and Cancer" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cancer Genomics |
| Discussion Leader: Yu Sun Chang (Chang Gung University, Taiwan) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:45 am | Andrew Futreal (University of Texas MD Anderson Cancer Center, USA) "Cancer Genomics and Evolution" |
9:45 am - 10:05 am | Discussion |
10:05 am - 10:30 am | Group Photo / Coffee Break |
10:30 am - 10:50 am | Jin-Xin Bei (Sun Yat-Sen University Cancer Center, China) "Genetic Basis of Nasopharyngeal Carcinoma" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Hong Zheng (The University of Hong Kong, Hong Kong SAR China) "Identification of Genetic Susceptibility Genes in Nasopharyngeal Carcinoma by Next-Generation Sequencing" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Kwok Wai Lo (The Chinese University of Hong Kong, Hong Kong SAR China) "NPC Genetics: Progressive Genomic Changes" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Lessons from an Epithelial Cancer |
| Discussion Leader: Ingemar Ernberg (Karolinska Institute, Sweden) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 8:15 pm | Elaine Fuchs (The Rockefeller University, USA) "Transition of Normal Epithelia to Cancer" |
8:15 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Mu Sheng Zeng (Sun Yat-Sen University Cancer Center, China) "NPC, an Epithelial Cancer: Immortalization and Tumorigenesis" |
9:15 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | EBV Genetics and Biology |
| Discussion Leader: Lori Frappier (University of Toronto, Canada) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:45 am | Henri-Jacques Delecluse (DKFZ - German Cancer Research Center, Germany) "Is NPC Caused by a Particular EBV?" |
9:45 am - 10:05 am | Discussion |
10:05 am - 10:30 am | Coffee Break |
10:30 am - 11:10 am | Richard Longnecker (Northwestern University, USA) "EBV Entry into Host" |
11:10 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | George Tsao (University of Hong Kong, Hong Kong SAR China) "Establishment of New NPC Xenografts and Cell Lines for EBV Studies" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
2:00 pm - 4:00 pm | Poster Session |
4:00 pm - 6:00 pm | Risk Factors and Cancer |
| Discussion Leader: Eric Stanbridge (University of California, Irvine, USA) |
4:00 pm - 4:05 pm | Introduction by Discussion Leader |
4:05 pm - 4:45 pm | Xin Lu (Ludwig Institute for Cancer Research, United Kingdom) "p53, a Key Regulator of Genomic Stability in Cancer" |
4:45 pm - 5:05 pm | Discussion |
5:05 pm - 5:45 pm | Allan Hildesheim (National Cancer Institute, NIH, USA) "Use of Viral and Genetic Markers for Risk Stratification for Development of Screening Programs for the Early Detection of NPC" |
5:45 pm - 6:00 pm | Discussion |
6:00 pm | Dinner |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | NPC Diagnostic Biomarkers |
| Discussion Leader: Pierre Busson (Institut Gustave Roussy, France) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:45 am | Fei-Fei Liu (Princess Margaret Hospital, Canada) "Prognostic Significance of miRNA Signatures for Detection of Metastatic NPC" |
9:45 am - 10:05 am | Discussion |
10:05 am - 10:25 am | Honglin Chen (University of Hong Kong, Hong Kong SAR China) "EBV BART miRNA and Serological Biomarkers for NPC" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:00 am | Coffee Break |
11:00 am - 11:40 am | Dennis Lo (Chinese University of Hong Kong, Hong Kong SAR China) "Plasma DNA Analysis for Detecting NPC: Biological Insights and Clinical Applications" |
11:40 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Wei Dai (The University of Hong Kong, Hong Kong SAR China) "Methylation Biomarkers in NPC" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Challenges for Primary Treatment of NPC |
| Discussion Leader: Anne Lee (The University of Hong Kong, Hong Kong SAR China) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 8:10 pm | Brian O'Sullivan (University of Toronto, Canada) "Challenges for Radiotherapy Treatment of NPC" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Roger Ngan (Queen Elizabeth Hospital, Hong Kong SAR China) "Evolution of NPC Clinical Trials in Hong Kong" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Jun Ma (Sun Yat-Sen Medical University, China) "NPC Clinical Trials in Guangzhou" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Innovative Therapies for NPC / Selected Poster Presentations |
| Discussion Leader: Rajiv Khanna (QIMR Berghofer Medical Research Institute, Australia) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:45 am | Cliona Rooney (Baylor College of Medicine, USA) "Cancer Immunotherapy and Challenges for NPC" |
9:45 am - 10:05 am | Discussion |
10:05 am - 10:30 am | Brigette Ma (Chinese University of Hong Kong, Hong Kong SAR China) "Novel Targets for NPC Treatment" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:10 am | Coffee Break |
11:10 am - 11:35 am | William Wei (Hong Kong Sanatorium & Hospital, Hong Kong SAR China) "Challenges for Surgical Management of Recurrent NPC" |
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Raymond Ng (University of Toronto, Canada) "Detection and Screening for NPC with Trans-Oral Brushing and Determination of EBV DNA" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Troy Messick (The Wistar Institute, USA) "Development of Small Molecule Inhibitors of EBNA1 for the Treatment of Nasopharyngeal Carcinoma" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Mhairi Morris (Faculty of Health and Life Sciences, De Montfort University, United Kingdom) "EBV-Encoded LMP1 Induces a Myofibroblast-Like Phenotype in Epithelial Cells via Epithelial-to-Mesenchymal Transition" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Future Prospects for NPC |
| Discussion Leader: Lawrence Young (University of Warwick, United Kingdom) |
4:00 pm - 4:10 pm | Introduction by Discussion Leader |
4:10 pm - 4:50 pm | Alan Rickinson (University of Birmingham, United Kingdom) "Future Focus for Basic NPC and EBV Studies" |
4:50 pm - 5:05 pm | Discussion |
5:05 pm - 5:45 pm | Quynh Le (Stanford University, USA) "Future Personalised Clinical Care for NPC Patients" |
5:45 pm - 6:00 pm | Discussion |
6:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |