Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Pathogenic Mechanisms and Novel Therapeutics
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
"Improving Plasma EBV DNA Analysis for Screening and Management of Nasopharyngeal Cancer"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
"Epithelial Cell Manipulation by Epstein-Barr Virus Lytic Proteins"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
EBV and NPC Pathogenesis and Epidemiology
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:40 am
"Systematic Characterization of Small Viral Proteins Reveals a Novel EBV Oncogene"
9:40 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Selective Targeting of EBV-associated NPC via Aptamer-Chemodrug Conjugates"
10:20 am - 10:30 am
Discussion
10:30 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
"Molecular Basis of Cellular Tropism in EBV Infection"
11:35 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Something Old and Something New About EBNA1"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Tumor Microenvironment and Targets
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"Tumour Heterogeneity and Intercellular Networks of Nasopharyngeal Carcinoma"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:10 pm
"Leveraging NPC Molecular Subtyping in an AI-Driven Platform for Novel Target Discovery"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Immunosequencing Identifies Signatures of T Cell Responses for Early Detection of Nasopharyngeal Carcinoma"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:40 am
"Viral Remodeling of the Cell Transcriptome during Lytic Replication"
9:40 am - 9:50 am
Discussion
9:50 am - 10:25 am
"Development of EBV Fluorescent Reporter Viruses to Study the Latent/Lytic Switch and Virus/Host Transcriptomes"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:45 am
"Architects of Latency: Host–Virus Chromatin Interactions in EBV-Associated Epithelial Cancer Cells"
11:45 am - 11:55 am
Discussion
11:55 am - 12:05 pm
Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"EBNA1 Inhibitors Reveal CDC7 and POU2F1 as Direct Functional Targets in EBV Epithelial Cancers"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:10 pm
"Epigenetic Crosstalk between Epstein-Barr Virus and Human Papillomavirus in Epithelial Tumor Progression"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Pathogenic Variants of Epstein-Barr Virus"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Immunology, Vaccines, Immunotherapy and Cell Therapy
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:40 am
"Development of EBV Vaccines"
9:40 am - 9:50 am
Discussion
9:50 am - 10:25 am
"Drug Development in Nasopharyngeal Carcinoma: Themes and Variations"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:45 am
"Late Stage Development of Novel Immunotherapy and Chemotherapy in the Treatment of R/M NPC"
11:45 am - 11:55 am
Discussion
11:55 am - 12:05 pm
Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Biomarkers, Individualized Therapy and Artificial Intelligence
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"AI and Big Data in Nasopharyngeal Carcinoma"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:10 pm
"SSTR2 as a Promising Theranostic Target in EBV-associated NPC"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Dynamic Plasma EBV DNA During Treatment and the Biomarker-driven, Risk-adaptive Systematic Therapy in Nasopharyngeal Carcinoma"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Clinical Trials and Novel Therapy
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:40 am
"Immunotherapy Resistance in Nasopharyngeal Carcinoma through a State of Endothelial Cell Energy"
9:40 am - 9:50 am
Discussion
9:50 am - 10:25 am
"Proton Therapy for the Management of NPC and Other Novel Radiotherapy Techniques"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:45 am
"Optimizing the Treatment Outcome of Locally Advanced NPC with Immune Checkpoint Inhibitors"
11:45 am - 11:55 am
Discussion
11:55 am - 12:05 pm
Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Future Challenges in Basic, Translational and Clinical Research
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:50 pm
"Prospective Issues in Core, Translational and Clinical Research"
6:50 pm - 7:05 pm
Discussion
7:05 pm - 7:45 pm
"Future Challenges in Global Harmonization of Clinical and Translational Research"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure