Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Novel Catalytic Strategies
7:40 pm - 8:05 pm
"Development of Novel Non-Precious Metal Catalyzed Methodologies for the Synthesis of Biologically Active Heterocyclic Compounds"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Transition Metal-Catalyzed Amination and Amidation Reactions"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Stereoselective Catalysis of Nucleophilic Substitution Reactions"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Discovery of Novel Natural Products
9:00 am - 9:30 am
"New Approaches for the Discovery of Microbial Natural Products"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Discovery of Novel Bioactive Polyketides/Non-Ribosomal Peptides from Microbes"
10:10 am - 10:20 am
Discussion
10:20 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
"Harnessing Genomic Information to Engineer the Biosynthesis of Natural Products"
11:10 am - 11:20 am
Discussion
11:20 am - 11:50 am
"Culture Independent Approaches for the Discovery of New Bacterial Metabolites"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Innovations in Drug Discovery
7:30 pm - 8:00 pm
"Correcting Disregulated Translation: Disciplined Structure-Based Inhibitor Design of eFT508 for the Treatment of Cancer"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Scaling Highly Potent Bifunctional Duocarmycin Derivatives for Treatment of Cancer"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Bioactivity and Mechanism of Action of N-Docosahexaenoylethanolamine Derivatives in Neuronal Development"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Natural Products Biosynthesis
9:00 am - 9:30 am
"Discovery and Engineering of Plant Chemistry"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Harnessing the Biosynthetic Capabilities of Marine Actinomycetes"
10:10 am - 10:20 am
Discussion
10:20 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
"Harnessing Plant Metabolic Diversity"
11:10 am - 11:20 am
Discussion
11:20 am - 11:50 am
"Engineered Polyketide Synthases for Production of Commodity and Specialty Chemicals"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Chemistry, Structure and Function of Complex Glycosides
7:30 pm - 8:00 pm
"New Chemical Biology Methods to Uncover the Functional Roles of Glycosylation"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Chemoenzymatic Synthesis of Glycoproteins for Probing Functions"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Chemistry to Explore and Exploit Microbial Carbohydrates for Health and Disease"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Structurally Complex Natural Products Synthesis
9:00 am - 9:30 am
"Synthesis of Complex Terpenes from Simple Precursors"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Chemical Synthesis of Secondary Metabolites"
10:10 am - 10:20 am
Discussion
10:20 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
"Total Synthesis of Polycyclic Natural Products"
11:10 am - 11:20 am
Discussion
11:20 am - 11:50 am
"Building Bridges: Strategies for the Synthesis of Complex Polycyclic Natural Products"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Rare and Neglected Disease Research
7:30 pm - 8:00 pm
"Collaborative Virtual Screening to Boost Neglected Tropical Disease Drug Discovery"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Discovery of Sequanamycin Derivatives as Potent Oral Anti-Tuberculosis Agents"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Bogged Down: An Ecology-Inspired Search for Novel Antituberculars"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
New Approaches to the Study of Bioactive Natural Products
9:00 am - 9:30 am
"Exploring the Master Regulators of Microbial Behavior"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Marine Natural Products Synthesis: A Driving Force for Chemical and Biological Discovery"
10:10 am - 10:20 am
Discussion
10:20 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
"Total Synthesis of Neurologically Active Terpenoid Natural Products"
11:00 am - 11:10 am
Discussion
11:10 am - 11:40 am
"Syntheses Through 'Seeding and Growing' Strategy Inspired by Molecular Pattern Recognition"
11:40 am - 11:50 am
Discussion
11:50 am - 12:20 pm
"Leveraging Carbene Catalysis for Complex Synthesis"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Strategies and Tactics for Chemical Synthesis
7:30 pm - 7:50 pm
"Unlocking Catalytic Promiscuity with Light: Non-Natural Free Radical Chemistry Within a Protein Active Site"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:30 pm
"From Radical Cations to Microelectrode Arrays to the Valorization of Lignin: Using Principles in Physical Organic Chemistry to Guide Electrochemical Solutions to Modern Synthetic Challenges"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
"New Photoredox Reactions"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure