| Sunday, June 6, 1999 |
| 2:00 pm-11:00 pm |
Registration and Check-in
(closed for dinner from 6:00 pm to 7:00 pm) |
| 6:30 pm-7:30 pm |
Dinner |
| 7:30 pm-9:00 pm |
Opening |
|
- Richard Johnson
Overview of Neurovirology
- Charles Weissman, Keynote Speaker
Molecular Biology of Prion Disease
|
| Monday, June 7, 1999 |
| 7:30 am-8:30 am |
Breakfast |
| 9:00 am-10:40 am |
Session I: HIV-1 Neuropathogenesis |
|
- David Volsky (Co-Chair)
Potential Role of Astrocyte Infection and Dysfunction in AIDS Dementia.
- Lynn Pulliam (Co-Chair)
Dementia: the Macrophage Connection.
- Janice Clements
SIV Model for HIV in the CNS
|
| 10:40 am-11:00 am |
Coffee Break |
| 11:00 am-12:30 pm |
Session I continued |
|
- Howard Gendelman
Investigating the Cellular and Molecular Neurobiology of HIV-1 Associated Dementia
- Chris Power
HIV or FIV Related Neuropathogenesis
|
| 12:30 pm-1:30 pm |
Lunch |
| 4:00 pm-6:00 pm |
Poster Session 1 |
| 6:00 pm-7:00 pm |
Dinner |
| 7:30 pm-9:30 pm |
Session II: Latency/Viral Persistency |
|
- Nigel Fraser (Chair)
Herpes Simplex Virus Latency Modeled in the Mouse Nervous System
- Michael Buchmeier
Pathogenesis of Coronavirus-Induced Demyelination
- Jay Nelson
Immunoreactivation of Human Cytomegalovirus
- Stephen Straus
Viral and Host Factors that Regulate the Latency and Reactivation of Herpes Simplex Viruses.
|
| Tuesday, June 8, 1999 |
| 7:30 am-8:30 am |
Breakfast |
| 9:00 am-10:30 am |
Session III: Signal Transduction in CNS |
|
- Howard Federoff (Chair)
Pathophysiologic Signaling in the CNS.
- Harris Gelbard
HIV-1 and Neurodegeneration: From Viral Genes to Neuronal Signal Transduction--
|
| 10:30 am-11:00 am |
Coffee Break |
| 11:00 am-11:45 pm |
Session III continued |
|
- Herbert Geller
Signal Transduction in Neuronal Apoptosis
|
| 11:45 am-12:30 pm> |
General Discussion Signal Transduction |
| 12:30 pm-2:00 pm |
Lunch |
| 4:00 pm-6:00 pm |
Poster Session 2 |
| 6:00 pm-7:00 pm |
Dinner |
| 7:30 pm-9:30 pm |
Session IV: Transmissible Encephalopathies |
|
- Thomas Weber Co-Chair
Introduction/Mad Cows and the Spectrum of Human Spongiform Encephalopathies (Prion diseases)
- Laura Manuelidis Session Co-Chair
Suppression and Recrudescence of a Virulent Strain of CJD.
- Bruce Chesebro
MultipleRoles of Prion Protein in the TSE Diseases
- John Collinge
Molecular Biology of Prion Propagation
|
| Wednesday, June 9, 1999 |
| 7:30 am-8:30 am |
Breakfast |
| 9:00 am-10:30 am |
Session V: Demyelinating Diseases
|
|
- Howard Lipton (Chair)
Mechanism(s) of Demyelination in Theiler's Virus Infection
- Robert Fujinami
Theiler's Viruses with Mutations in the Loops of VP1 and VP2 Lead to Altered Tropism and Pathogenesis
|
| 10:30 am-11:00 am |
Coffee Break |
| 11:00 am-12:30 pm |
Session V continued |
|
- John Henson
Mechanisms of Oligodendrocyte-Specific Viral Infection in Humans
- Stanley Perlman
Role of CTL Escape Mutants in MHV-Induced Demyelination
|
| 12:30 pm-1:30 pm |
Lunch |
| 4:00 pm-6:00 pm |
Poster Session 3 |
| 6:00 pm-7:00 pm |
Dinner |
| 7:30 pm - 9:30 pm |
Session VI: Neurotropic Virus: New Links to CNS Disease |
|
- Steve Jacobson Session Chair
Immunopathogenesis of HTLV-1 Associated Neurological Disease: Lessons for our Understanding of Multiple Sclerosis
- Ruth Itzhaki
The Role of Herpesviruses in Alzheimer's Disease
- Sidney Croul
Recent Findings in the Association Between Neurotropic Viruses and Pediatric Brain Tumors
- Ian Lipkin
Mechanisms of Bornavirus neuropathogenesis: Insights into Neuropsychiatric Diseases
|
| Thursday, June 10, 1999 |
| 7:30 am-8:30 am |
Breakfast |
| 9:00 am-10:30 am |
Session VII: Molecular and Cellular Therapeutic Strategies for CNS Disease |
|
- Eugene O. Major (Chair)
Alternative Methods for Gene Delivery of Therapeutic Molecules in the CNS.
- Antonio Chiocca
Replication-Conditional HSV-1 Mutants: Potential Agents Against Cancer
|
| 10:30 am-11:00 am |
Coffee Break |
| 11:00 am-12:30 pm |
Session VII continued |
|
- Darwin J. Prockop
Stromal cells from Bone Marrow as Therapeutic Vectors for the Central Nervous System
- David Fink
Using Genomic Herpes Virus Vectors to Alter Structure and Function of the Nervous System
|
| 12:30 pm-1:30 pm |
Lunch |
| 5:00 pm-6:00 pm |
General Discussion on field of Neurovirology, International Society of Neurovirology, and 2001 Gordon Research Conference on Neurovirology |
| 6:00 pm-8:00 pm |
Dinner |
| Friday, June 11, 1999 |
| 7:30 am-8:30 |
Breakfast
Conference ends. Buses depart for Logan Airport in Boston after breakfast. |
