Saturday
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2:00 pm - 5:00 pm |
Arrival and Check-in
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3:30 pm - 3:45 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
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3:45 pm - 4:30 pm |
Keynote Session: Post-Translational Modifications in the Notch Signaling Pathway
Discussion Leader: Daniel Lafkas (Genentech Inc., USA)
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3:45 pm - 4:15 pm |
Pamela Stanley (Albert Einstein College of Medicine, USA)
"Roles of Glycosylation in Notch Signaling"
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4:15 pm - 4:30 pm |
Discussion
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4:30 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Dynamic Control of Cell Fate and Function
Discussion Leaders: Qi Yang (Albany Medical College, USA), Adrian Jacobo (Rockefeller University, USA) and ChangHwan Lee (University of Wisconsin-Madison / Howard Hughes Medical Institute, USA)
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7:30 pm - 7:45 pm |
Eric Perkey (University of Michigan, USA)
"Specialized Fibroblasts in Secondary Lymphoid Organs Program Effector T Cell Responses Through Notch Signals in Graft-Versus-Host Disease and Other Immunological Contexts"
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7:45 pm - 7:50 pm |
Discussion
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7:50 pm - 8:05 pm |
Joshua Adams (Baylor College of Medicine, USA)
"Sox9 Levels Determine the Severity and Progression of Liver Disease in a Mouse Model of Alagille Syndrome"
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8:05 pm - 8:10 pm |
Discussion
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8:10 pm - 8:25 pm |
Craig Jacobs (University of Calgary, Canada)
"PHRESH Analysis Reveals a Role for Notch Signalling in the Maintenance of Hh Response During Spinal Cord Patterning"
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8:25 pm - 8:30 pm |
Discussion
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8:30 pm - 8:45 pm |
Emilie Abby (Wellcome Trust Sanger Institute, United Kingdom)
"Elucidating the Cellular and Molecular Effects of Notch1 Inactivating Mutations in the Oesophagus"
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8:45 pm - 8:50 pm |
Discussion
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8:50 pm - 9:05 pm |
Oscar Stassen (Eindhoven University of Technology, The Netherlands)
"A Biomimetic Cardiovascular-Tissue-on-a-Chip to Study the Interplay Between Notch Signalling and Hemodynamic Loading"
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9:05 pm - 9:10 pm |
Discussion
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9:10 pm - 9:25 pm |
Roshana Thambyrajah (Fundació IMIM, Spain)
"How Much Notch Is Enough for HSC Generation?"
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9:25 pm - 9:30 pm |
Discussion
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Sunday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 11:00 am |
Structural Mechanics and Signaling
Discussion Leaders: Vincent Luca (Moffitt Cancer Center & Research Institute, USA), David Sloas (Boston University, USA) and Anna Erzberger (The Rockefeller University, USA)
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9:00 am - 9:15 am |
Julia Falo-Sanjuan (University of Cambridge, United Kingdom)
"Dynamics of Transcription from Notch-Responsive Enhancers"
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9:15 am - 9:20 am |
Discussion
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9:20 am - 9:35 am |
ChangHwan Lee (University of Wisconsin-Madison / Howard Hughes Medical Institute, USA)
"Dynamics of Notch-Dependent Transcriptional Activation in Its Natural Context"
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9:35 am - 9:40 am |
Discussion
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9:40 am - 9:55 am |
Eleni Foteinou (University of Manchester, United Kingdom)
"Classifying Mutant Outcomes Arising from Different EGF Domain Mutations Within the Ligand Binding Region of Notch"
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9:55 am - 10:00 am |
Discussion
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10:00 am - 10:15 am |
Giulia Monticone (University of Manchester, United Kingdom)
"Cancer-Associated Mutations Affect Notch Endocytic Trafficking"
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10:15 am - 10:20 am |
Discussion
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10:20 am - 10:35 am |
Adrian Jacobo (Rockefeller University, USA)
"Notch-Mediated Polarity Decisions in the Zebrafish's Lateral Line"
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10:35 am - 10:40 am |
Discussion
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10:40 am - 10:55 am |
Udi Binshtok (Tel Aviv University, Israel)
"Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning"
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10:55 am - 11:00 am |
Discussion
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11:00 am - 12:30 pm |
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 2:30 pm |
Mentorship Component: From Surviving to Thriving in Research
Discussion Leader: Rachel LoPilato (University of Georgia, USA)
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1:30 pm - 2:30 pm |
Panel Discussion
From Surviving to Thriving in Research
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Vincent Luca (Moffitt Cancer Center & Research Institute, USA)
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David Sprinzak (Tel Aviv University, Israel)
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Qi Yang (Albany Medical College, USA)
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2:30 pm - 3:00 pm |
Evaluation Period
Fill in GRS Evaluation Forms
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3:00 pm |
Seminar Concludes
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