Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Channels and Transporters in Chloroplasts
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:05 pm
"Metabolite Fluxes Between Cytosol and Chloroplast"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Role of the Magnesium Transporter MGT10 in Chloroplast Development and Photosynthesis"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Metabolite Transport in Photosynthesis"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Isolation of Acidocalcisomes from Dunaliella bardawil "
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Channels and Transporters in Mitochondria
9:00 am - 9:20 am
"Structure and Function of Mitochondrial Complexes: The Molecular Mechanism of Complex I"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Spatiotemporal Dynamics of OXPHOS Complexes in Live Cells"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"NAD+ Transport into Mitochondria"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Mitochondrial Carboxylate Transporters and Regulation of Macronutrient Metabolism"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Mitochondrial Import of S-Adenosyl Methionine and the Mitochondrial Methylproteome"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Molecular Identity and Regulatory Mechanisms of the Mitochondrial Uncoupling Protein of Regular Somatic Tissues"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Unique Functional Properties of Mitochondria Bound to Lipid Droplets"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Ion Homeostasis Established by Organelle Transporters
7:30 pm - 7:50 pm
"Physiological Roles of Endo-Lysosomal Chloride/Proton Exchangers"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Organellar Transporters Controlling Iron and Manganese Homeostasis in Plants"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Ion Homeostasis in Rice"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Roles of Vacuolar NHX-Type Transporters in Plant Growth and Development"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Channels and Transporters in Vacuoles and Endo-Lysosomes
9:00 am - 9:20 am
"Structure and Regulation of the Yeast Vacuolar H+ -ATPase"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Control of Phosphate Homeostasis by Acidocalcisome-Like Vacuoles"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"A New Pathway for Degrading Lysosomal Transporters"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Agonist-Selective Permeability in an Intracellular Ion Channel"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Down-Regulation of Lysosome Membrane Transporters in Yeast"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"PQLC2 Signals Lysosomal Cationic Amino Acid Abundance to the C9orf72 Complex"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Organellar DNA Reporters for Discovery Biology"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Organelle Membrane Transport in Calcium Signaling
7:30 pm - 7:50 pm
"Cryo-EM Study of the Mitochondrial Calcium Uniporter"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"X-Ray and Cryo-EM Study of the Mitochondrial Calcium Uniporter"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Unique Mode of Regulation of the Mitochondrial Na+ /Ca2+ Exchanger NCLX"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Calcium and Long-Distance Signaling in Plants"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Transferring Lipids Across and Between Organelle Membranes
9:00 am - 9:20 am
"VPS13 and Chorein_N Motif Proteins Function in Lipid Transfer"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Lipid Transporting ABC Transporters in Plant"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Structural Investigation of SSD Proteins in Sterol Sensing and Transport"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Transduction of the Hedgehog Signal from Patched to Smoothened"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Structural Basis for Sterol Transporter-Like Activity of the Hedgehog Receptor PTCH1"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Remote Control of Inter-Organellar Membrane Contact Sites Using Optogenetic Tools"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Structural Insights and Autoregulation of a P4-ATPase Lipid Flippase"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Channels and Transporters in the Nucleus and Secretory Pathway
7:30 pm - 7:50 pm
"Molecular Insights into the Regulation of the TRP Channel Polycystin-2"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"A Calcium/cAMP Signaling Loop at the ORAI1 Mouth Drives Channel Inactivation to Shape NFAT Induction"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Comparison of the Vacuolar and Golgi V-ATPases from Saccharomyces cerevisiae "
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Vesicular Nucleotide Transporter (VNUT) as a Target for Drug Discovery"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Different Modes of Ionic Coupling by a Family of Organic Anion Transporters"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Organellar Transport Proteins in Human Diseases
9:00 am - 9:20 am
"The Role of Primary Cilium Ion Channels in Cancer"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Why Succinate? A Model for Systemic Bioenergetic Signaling"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"The Mitochondrial Protein VDAC1 as a Target for Cancer, Neurodegenerative, Diabetes and Autoimmune Diseases"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Pathophysiology of Endolysosomal Disorders in the Kidney"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"SK Channel Activation Prevents Ferroptosis by Metabolic Reprogramming"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Endosomal pH Regulator Sodium Hydrogen Exchanger Isoform 9 Maintains Glioblastoma Stem Cells by Stabilizing Multiple Receptor Tyrosine Kinases"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Protons to Patients: Insights into ClC-7 Function from a Novel Disease Mutation"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Organelle Integration of Metabolism and Signaling
7:30 pm - 7:50 pm
"Dynamic Organization of Intracellular Organelle Networks"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Integration of Retrograde, ROS and ABA Signalling Across Evolutionary Scales"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Crosstalk Between Lysosomes and Mitochondria in mTOR Signaling"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Metabolic Control of Sleep"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure