| Sunday - July 12, 1998 |
| 6:00 P.M. |
Dinner |
| 7:15 |
Welcome and Introductory Remarks |
| Session 1 |
Russ Linderman, Discussion Leader |
| 7:30 |
Peter Wipf - University of Pittsburgh
New Stereoselective Transition Metal - Catalyzed Transformations |
| 8:15 |
Discussion |
| 8:30 |
Break |
| 8:45 |
Scott Denmark - University of Illinois
New Concepts for Asymmetric Catalysis |
| 9:30 |
Discussion |
| Monday - July 13, 1998 |
| 7:30 A. M |
Breakfast |
| Session 2 |
Kay Brummond, Discussion Leader |
| 8:20 |
Announcements |
| 8:30 |
Peter Jacobi - Dartmouth College
The Nicholas Reaction in Natural Product Synthesis |
| 9:15 |
Discussion |
| 9:30 |
Cynthia Maryanoff - R. W. Johnson
Synthesis of Novel Heterocycles |
| 10:00 |
Discussion |
| 10:15 |
Break |
| Session 3 |
John Janusz, Discussion Leader |
| 10:30 |
Kenneth Wiberg - Yale University
Solvent Effects on Organic Reactions |
| 11:15 |
Discussion |
| 11:30 |
Kendall Houk - University of California-Los Angeles
Theory and the Diels-Alder Reaction Mechanism: From Femtosecond Dynamics to Catalytic Antibodies |
| 12:15 |
Discussion |
| 12:30 |
Lunch |
| 4:00 - 6:00 |
Poster Session 1 |
| 6:00 |
Dinner |
| Session 4 |
Mukund Sibi, Discussion Leader |
| 7:15 |
Daniel Comins - North Carolina State University
Asymmetric Synthesis and Synthetic Utility of Dihydropyridones |
| 8:00 |
Discussion |
| 8:15 |
Break |
| 8:30 |
John Montgomery - Wayne State University
Short Talk: Nickel-Catalyzed Cyclizations and Multicomponent Couplings |
| 8:45 |
Discussion |
| 9:00 |
Samuel Danishefsky - Columbia University and Sloan Kettering Institute for Cancer Research
Recent Findings in the Synthesis of Biologically Active Natural Products |
| 9:45 |
Discussion |
| 10:30 |
Late Night |
| Tuesday - July 14, 1998 |
| 7:30 A. M. |
Breakfast |
| Session 5 |
Nanette Wachter-Jurcsak, Discussion Leader |
| 8:20 |
Announcements |
| 8:30 |
Photo Session |
| 9:00 |
Cynthia Burrows - University of Utah
The Chemistry and Biochemistry of Guanine Oxidation |
| 9:45 |
Discussion |
| 10:00 |
Dominic McGrath - University of Connecticut
Short Talk: Controlling Dendrimers with Light |
| 10:15 |
Discussion |
| 10:30 |
Break |
| Session 6 |
Bill Berkowitz, Discussion Leader |
| 10:45 |
Jacqueline Barton - California Institute of Technology
DNA-Mediated Electron Transfer |
| 11:30 |
Discussion |
| 11:45 |
Eric Moher - Eli Lilly & Company
Synthetic Studies on the Anti-tumor Agent Cryptophycin 52 (LY355703) |
| 12:15 |
Discussion |
| 12:30 |
Lunch |
| 1:30 |
3rd Annual OR&P Golf "Classic" |
| Session 7 |
John Dillon, Discussion Leader |
| 7:15 |
Alexandre Alexakis - Université P. et M. Curie
New Developments in Chiral Diamine Chemistry |
| 8:00 |
Discussion |
| 8:15 |
Break |
| 8:30 |
Jollie Godfrey - Bristol-Myers Squibb
Process Research and Development of BMS 180448, a Cardioselective Potassium Channel Activator |
| 9:00 |
Discussion |
| 9:15 |
Paul Herrinton - Pharmacia & Upjohn
Reliable Synthesis for Preparation of Taxane PNU-105298 |
| 9:45 |
Discussion |
| 10:00 |
Business Meeting and Nominations |
| 10:30 |
Late Night |
| Wednesday - July 15, 1998 |
| 7:30 A. M. |
Breakfast |
| Session 8 |
Timo Ovaska, Discussion Leader |
| 8:20 |
Announcements |
| 8:30 |
James Zeller - Parke-Davis
Process Development and Large Scale Synthesis of a New Drug Candidate |
| 9:00 |
Discussion |
| 9:15 |
Richard Taylor - University of Notre Dame
Short Talk: Structural Diversity with Oligocyclopropane-Based Scaffolds |
| 9:30 |
Discussion |
| 9:45 |
Amy Howell - University of Connecticut
Short Talk: 2-Alkylidene Oxetanes: Useful Molecular Scaffolds |
| 10:00 |
Discussion |
| 10:15 |
Break and Election of Chair for 2000 |
| Session 9 |
Sean Nugent, Discussion Leader |
| 10:30 |
Kyoko Nozaki - Kyoto University
Asymmetric Hydorformylation of Olefins |
| 11:15 |
Discussion |
| 11:30 |
Gregory Cook - North Dakota State University
Short Talk: Palladium-Catalyzed Dynamic Kinetic Resolution: A Stereoselective Synthesis of 1,2-Diamines |
| 11:45 |
Discussion |
| 11:50 |
Timo Ovaska - Connecticut College
Short Talk: A Novel Approach to Fused 5-7-6 Tricyclic Ring Systems |
| 12:05 |
Discussion |
| 12:30 |
Lunch |
| 4:00 - 6:00 |
Poster Session 2 |
| 6:00 |
Dinner |
| Session 10 |
Mike Harmata, Discussion Leader |
| 7:10 |
Election Results |
| 7:15 |
Reinhard Brückner - Universität Göttingen
New Pathways to Butyrolactones and Butenolides |
| 8:00 |
Discussion |
| 8:15 |
Break |
| 8:30 |
Vladimir Gevorgyan - Tohoku University
Short Talk: Synthesis of Polysubstituted Benzenes via Novel Palladium-Catalyzed Benzannulation Reactions |
| 8:45 |
Discussion |
| 9:00 |
Shon Pulley - University of Missouri-Columbia
Short Talk: Benzannulation Strategies Toward C-Arylglycosides and Biarylethers |
| 9:15 |
Discussion |
| 10:00 |
Late Night |
| Thursday - July 16, 1998 |
| 7:30 A. M. |
Breakfast |
| Session 11 |
Amy Howell, Discussion Leader |
| 8:20 |
Announcements |
| 8:30 |
Tony Barrett - Imperial College
Recent Applications of Catalysis in Organic Synthesis |
| 9:15 |
Discussion |
| 9:30 |
Peter Dunn - Pfizer UK
Asymmetric Michael Addition Reactions: Don't Worry About Scale-up |
| 10:00 |
Discussion |
| 10:15 |
Break |
| Session 12 |
Ed Grabowski, Discussion Leader |
| 10:30 |
Richard Tillyer- Merck & Co.
Recent Developments in Practical Asymmetric Synthesis |
| 11:00 |
Discussion |
| 11:15 |
Amos Smith - University of Pennsylvania
Recent Advances in the Total Synthesis of Architecturally Complex Natural Products |
| 12:00 |
Discussion |
| 12:30 |
Lunch |
| 2:00 |
Annual Academic / Industrial Softball Game |
| 4:00 - 6:00 |
Chair's Reception - Wine Tasting |
| 6:00 |
Dinner |
| Session 13 |
Terry Rathman, Discussion Leader |
| 7:30 |
Jeffrey Seeman - Philip Morris Research Center
The Human Side of Organic Chemistry: A Photographic Tour |
| 9:00 |
Discussion |
| 9:15 |
Closing Remarks |
| Friday - July 17, 1998 |
| 7:30 A. M. |
Breakfast |
| 9:00 |
GRC Chartered Bus Departs for Boston |
