| SUNDAY |
| 6:00 PM | Dinner |
| 7:20 | Welcome and Introductory Remarks |
| 7:30 - 9:30 pm | Catalysis |
| Discussion Leader: Jeffrey N. Johnston (Indiana University) |
| 7:30 | Thomas Lectka (Johns Hopkins University)
Asymmetric catalysis with Zwitterionic enolates: from beta-lactam synthesis to enantioselective halogenation |
| 8:00 | Discussion |
| 8:10 | Varinder Aggarwal (University of Bristol)
"Catalytic Asymmetric Epoxidations and Related Reactions" |
| 8:40 | Discussion |
| 8:50 | Hisashi Yamamoto (Nagoya University)
"Super Lewis Acid Catalysis for Organic Synthesis" |
| 9:35 | Discussion |
| MONDAY |
| 7:30 AM | Breakfast |
| 8:30 | Photo Session |
| 9:00 am - | Process Chemistry |
| Discussion Leader: Ann Gelormini (R.W. Johnson Pharmaceutical Research Institute) |
| 9:00 | Steve Wittenberger (Abbott)
"Abbott Laboratories Influenza Neuraminidase Inhibitor: Process Research and Initial Scale-up" |
| 9:30 | Discussion |
| 9:40 | Suzanne Kiau (Bristol-Meyer Squibb)
"Crystallization-Driven Dynamic Resolution of a-Substituted Carboxylic Acids: Applications, Mechanistic Investigations and the Role of Polymorphs" |
| 10:00 | Discussion |
| 10:10 | Break |
| 10:30 am - 12:30 pm | Organometallic Chemistry |
| Discussion Leader: Jim Green (University of Windsor) |
| 10:30 | Vladimir Gevorgyan (University of Illinois at Chicago)
"Development of Novel Metal-Catalyzed Annulation Methodologies" |
| 10:50 | Discussion |
| 11:00 | William Donaldson (Marquette University)
"Group 8 Metal Mediated/Catalyzed Transformations" |
| 11:20 | Discussion |
| 11:30 | James Takacs (University of Nebraska)
"Catalytic Metal-Mediated Carbocyclizations: Selected Applications in Asymmetric Synthesis" |
| 12:20 | Discussion |
| 12:30 | Lunch |
| 4:00-6:00 | Poster Session I |
| 6:00 PM | Dinner |
| 7:30 - 9:30 pm | Catalysis |
| Discussion Leader: Chris Senanayake (Sepracor) |
| 7:30 | Neil Boaz (Eastman Chemical Company)
"BoPhoz Ligands for Asymmetric Catalysis" |
| 8:00 | Discussion |
| 8:10 | T.V. RajanBabu (Ohio State University)
"Practical Asymmetric Catalysis: New Ligands and New Control Elements" |
| 8:40 | Discussion |
| 8:50 | Andreas Pfaltz (University of Basel)
"Recent Progress in Asymmetric Hydrogenation" |
| 9:35 | Discussion |
| TUESDAY |
| 7:30 AM | Breakfast |
| 8:45 | Announcements |
| 8:45 - 10:25 am | Radical Chemistry |
| Discussion Leader: Amy Howell (University of Connecticut) |
| 8:45 | Dan Yang (University of Hong Kong)
"Design and Applications of Catalytic Asymmetric Radical Cyclization Reactions" |
| 9:15 | Discussion |
| 9:25 | Greg Friestad (University of Vermont)
"Versatile Asymmetric Amine Synthesis via the Carbon-Carbon Disconnection" |
| 9:45 | Discussion |
| 9:55 | Break |
| 10:10 am - 12:30 pm | Catalysis and Radical Chemistry |
| Discussion Leader: Jean Suffert (CNRS) |
| 10:10 | Jon Lawson (Pharmacia)
"Bile Acid Transport Inhibitor Process Development" |
| 10:30 | Discussion |
| 10:40 | Sergey Kozmin (University of Chicago)
"New Methods for Multiparallel and Complex Target Synthesis" |
| 11:00 | Discussion |
| 11:10 | Li Deng (Brandeis University)
"Asymmetric Catalysis of Modified Cinchona Alkaloids" |
| 11:30 | Discussion |
| 11:40 | Max Malacria (University of Paris)
"Highly Stereoselective Radical and Transition Metal Catalyzed Polycyclization Reactions" |
| 12:20 | Discussion |
| 12:30 | Lunch |
| 1:30 | ORP Golf Classic |
| 6:00 PM | Dinner |
| 7:30 - 9:30 pm | Catalysis |
| Discussion Leader: Xumu Zhang (Pennsylvania State University) |
| 7:30 | Lushi Tan (Merck)
Synthesis of highly substituted butenolides |
| 8:00 | Discussion |
| 8:10 | Marisa Kozlowski (University of Pennsylvania)
"Bifunctional Catalysts Based on Salen Metal Complexes" |
| 8:40 | Discussion |
| 8:50 | Karl Anker Jorgenson (Aarhus University, Denmark)
"New Catalytic Asymmetric Reactions" |
| 9:35 | Discussion |
| WEDNESDAY |
| 7:30 AM | Breakfast |
| 8:45 | Nomination for 2004 Conference Chair |
| 8:45 - 10:25 am | New Reactions |
| Discussion Leader: Kay Brummond (University of Pittsburgh) |
| 8:45 | Carmen Najera (University of Alicante)
"Oxime-Derived Palladacycles as Efficient Catalysts for Cross-Coupling and Annulation Reactions" |
| 9:15 | Discussion |
| 9:25 | Vilas Dahanukar (Schering-Plough)
"Scale up and Understanding of a Aziridinium Reaction in the Synthesis of D1 Antagonist Sch 39166" |
| 9:45 | Discussion |
| 9:55 | Break |
| 10:10 am - 12:30 pm | New Reactions |
| Discussion Leader: Brian Pagenkopf (University of Texas) |
| 10:10 | Robert Singer (Pfizer, Groton)
"Development of a Preclinical Candidate to Avoid Benzyne Chemistry" |
| 10:30 | Discussion |
| 10:40 | Peter Beak (University of Illinois)
"Asymmetric Reaction Pathways: Asymmetric Deprotonations, Dynamic Kinetic Resolutions and Dynamic Thermodynamic Resolutions" |
| 11:25 | Discussion |
| 11:35 | Tamio Hayashi (Kyoto University)
"Rhodium Catalyzed Asymmetric Carbon-Carbon Bond Forming Reactions" |
| 12:20 | Discussion |
| 12:30 | Lunch |
| 4:00 | Poster Session II |
| 6:00 PM | Dinner |
| 7:30 - 9:30 pm | Synthesis |
| Discussion Leader: Jon Rainier (University of Arizona) |
| 7:30 | Thomas R. Hoye (University of Minnesota)
"Powerful but Practical NMR Methods for Studying Organic Structures, Reactions and Processes" |
| 8:00 | Discussion |
| 8:10 | Michael Crimmins (University of North Carolina)
"Asymmetric Synthesis of Heterocyclic Marine Natural Products" |
| 8:40 | Discussion |
| 8:50 | Amos B. Smith III (University of Pennsylvania)
"Recent Advances in the Construction of Architecturally Complex Natural and Unnatural Products" |
| 9:35 | Discussion |
| THURSDAY |
| 7:30 AM | Breakfast |
| 8:45 am | Election of 2004 Conference Chair |
| 8:45 - 10:40 am | New Reactions |
| Discussion Leader: Michael Sommer (H. Lundbeck A/S, Denmark) |
| 8:45 | Martin O'Donnell (Indiana University Purdue University)
"Unnatural Amino Acid and Peptide Synthesis" |
| 9:15 | Discussion |
| 9:25 | Scott May (Eli Lilly)
"Synthesis of 2-Aryl-1-Naphthols via a Novel Palladium-Mediated Alpha Arylation/Oxidation Reaction" |
| 9:45 | Discussion |
| 9:55 | Break |
| 10:10 am - 12:30 pm | New Reactions |
| Discussion Leader: Richard Hsung (University of Minnesota) |
| 10:10 | William Kissel (Pfizer, Holland)
"Asymmetric Hydrogenation, a New Route to Pregabalin" |
| 10:30 | Discussion |
| 10:40 | Cathleen Crudden (Queens University)
"The Synthesis of 2-Arylpropionic Acids and other Medicinal Compounds via an Asymmetric Hydroboration/Homologation Sequence" |
| 11:00 | Discussion |
| 11:10 | Andrew Whitehead (GlaxoSmithKline)
Synthetic challenges faced in the development of chiral benzothiazepines as bile acid transport inhibitors |
| 11:30 | Discussion |
| 11:40 | Short Talk from Poster |
| 12:00 | Discussion |
| 12:05 | Short Talk from Poster |
| 12:25 | Discussion |
| 12:30 | Lunch |
| 1:30 | Soft Ball |
| 4:00 PM | Chair's Reception - Wine and Cheese |
| 7:30 - 9:30 pm | Featured Speaker |
| Discussion Leader: Christopher Schmid (Eli Lilly) |
| 7:30 | Featured Speaker
Dr. Lawrence Krauss (Case Western University)
Life, the Universe, and Nothing: the future of life in an ever expanding universe... |
