Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Chemistry, Connectivity, Computation
7:40 pm - 8:10 pm
"Advancing Process Chemistry at AbbVie: Harnessing Catalysis, High-Throughput Experimentation, and Machine Learning"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"Supramolecular Principles in Catalyst Design: Merging H-Bond Donors and Gold Catalysis"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Molecular Innovation Through Sustainable Catalysis: Advancing Resource-Efficient Chemical Synthesis"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Process Design Through Mechanistic Considerations
9:00 am - 9:30 am
"Advances in Acetal Radical Chemistry"
9:30 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Process Development of Novel Drug-Linkers from Pfizer"
10:05 am - 10:15 am
Discussion
10:15 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
"Mechanistic Investigations Into Modern Catalytic Reactions"
11:10 am - 11:20 am
Discussion
11:20 am - 11:45 am
"Studies in Discovery Process"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Process Development at FMC"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Environmental Considerations and Green Chemistry as Design Principles
7:30 pm - 8:00 pm
"Biocatalysis Process Intensification Targeting Large Scale Ethanol Oxidation"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"New Strategies for Stereoselective Radical Biocatalysis"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Transfer Learning for a Foundational Chemistry Model in Synthesis and Methodology"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Design of Selective Processes
9:00 am - 9:25 am
"Stereoselective Synthesis of Active Pharmaceutical Ingredients"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Biomimetic Catalytic Enantioselective Oxidation"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:05 am
"Control of Reactivity and Selectivity With Spirobipyridine Ligands"
11:05 am - 11:15 am
Discussion
11:15 am - 11:40 am
"Towards Highly Convergent Synthesis of N-Alkyl-Rich Peptides: Development of Two Complementary Epimerization-Resistant Fragment Coupling Reactions"
11:40 am - 11:50 am
Discussion
11:50 am - 12:20 pm
"Catalysis to Increase Complexity: Stereoselective Methods to Prepare sp3-Rich Building Blocks"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Innovative Technologies as Design Principles
7:30 pm - 8:00 pm
"Electrosynthesis for Amination and Radical-Based Organoboron Coupling Reactions"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Selective Synthesis Using Light and Electricity"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Mechanochemistry Is Like Regular Chemistry, but Different"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Design of Process-Applicable Chemical Transformations and Methods
9:00 am - 9:25 am
"Improved Process for Improved API"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Process Chemistry in the Age of Information"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Development of Efficient Routes to 6-Aryl Picolinate Herbicides"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"A Continuous Processing Approach to the Preparation and Multikilogram Production of GPhos"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Discovery and Development of a Direct Amidation Process"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:25 pm
"Simplifying Synthesis Through Polarity-Mismatched Radical Chemistry"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Design of Catalytic Systems
7:30 pm - 8:00 pm
"Synthesis of Polycyclic Terpenoids and Alkaloids"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Late-Stage Modification of Serines for Non-Canonical Peptide Synthesis"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Catalysis With High-Valent Metals"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Chemistry in the Information Age: New and Groundbreaking Work from Early Career Scientists
9:00 am - 9:10 am
Short Talk Selected from Poster Abstracts
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Short Talk Selected from Poster Abstracts
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
"The Design and Application of New Pericyclic Strategies"
11:10 am - 11:20 am
Discussion
11:20 am - 11:45 am
"Structure Without Barriers: Why Should Synthetic Chemists Care About MicroED?"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"New Reactions of Radicals With Ions and in Excited States"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: Rational Design in Synthesis and Catalysis
7:30 pm - 8:00 pm
"Streamlining Catalytic Reaction Analysis With In-Situ Kinetic Measurements"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Saturared N/O-Heterocycles for Medicinal Chemistry"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Rhodium-Catalyzed Reactions of Donor/Acceptor Carbenes: From Academic Curiosity to Pharmaceutical Applications"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure