| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:50 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:50 pm - 9:30 pm | From Scenarios to Schemas: Robust Models for Life’s Origins |
| Discussion Leader: Robert Hazen (Carnegie Institution) |
| 7:50 pm - 8:25 pm | Shelley Copley (Univ. of Colorado) "False Dichotomies and the Origin of Life" |
| 8:25 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:15 pm | John Baross (Univ. of Washington) "History of the Major Ideas for the Origin of Life on
Earth" |
| 9:15 pm - 9:30 pm | Discussion |
| 9:30 pm | Wine reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Real World Geochemical Complexity: Interfaces, Gradients and Cycles |
| Discussion Leader: John Baross (University of Washington, Seattle) |
| 9:00 am - 9:20 am | Ariel Anbar (Arizona State Univ.) "The Role of P and As: Geochemical Aspects" |
| 9:20 am - 9:40 am | Felicia Wolfe-Simon (Harvard Univ.) "The Role of P and As: Biochemical Aspects" |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am - 10:30 am | Coffee Break / Group Photo |
| 10:30 am - 11:00 am | Victoria Orphan (Caltech) "Microscale Biosignatures:Carbon and Sulfur Cycling in Extreme Environments" |
| 11:00 am - 11:10 am | Discussion |
| 11:10 am - 11:40 am | Kevin Zahnle (NASA Ames) "Conditions on the Early Earth" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:20 pm | Michael Russell (NASA Ames) "The Alkaline Solution to the Emergence of Life" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session / Wine Mixer |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Alternative Planetary Environments for Life |
| Discussion Leader: Dirk Schulze-Makuch (Washington State University, Pullman) |
| 7:30 pm - 7:50 pm | Dirk Schulze-Makuch (Washington State) "Venus, Mars...and What’s Life Got to Do with It?" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Darlene Lim (NASA Ames) "Astrobiology and Mars Analogue Research in the Canadian High Arctic" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Athena Coustenis (Observatoire de Meudon, France) "Exploring Titan and Enceladus for their Astrobiological Potentials" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Steve Benner (Foundation for Applied Molecular Evolution, Florida) "Chemical
Constraints on the Structure of Alien Biochemistries" |
| 9:20 pm - 9:30 pm | Discussion |
| 9:30 pm | Continued informal discussion and wine at the poster session |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Early Chemical Steps on the Road to Life’s Origins |
| Discussion Leader: George Cody (Carnegie Institution) |
| 9:00 am - 9:30 am | George Cody (Carnegie Institution) "Early Chemical Steps on the Road to Life’s Origins" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:15 am | Eric Smith (Santa Fe Institute) "Statistical Thinking and Plausible Theories of the Origin of Life" |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Shelley Copley (University of Colorado) "The Origin of the RNA World: Co-Evolution of Genes and Metabolism" |
| 11:30 am - 11:45 am | Discussion |
| 11:45 am - 12:15 pm | Simon Nicholas Platts (Carnegie Institution) "Discotic Polynuclear Aromatic Compounds as Mesophase Scaffolding for the Earliest Conceivable Pre-RNAs" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Metabolism First: An Abundance of Worlds |
| Discussion Leader: Robert Shapiro (New York University) |
| 7:30 pm - 7:55 pm | Robert Shapiro (New York University) "A Simpler Origin of Life" |
| 7:55 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:35 pm | Arthur Weber (SETI Institute, NASA Ames Research Center) "Sugar World Chemistry: Sugars as the Source of Energized Carbon for the Origin of Life" |
| 8:35 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:15 pm | Irene Chen (Harvard University) "Cell-like Behaviors of Primitive Lipid Vesicles" |
| 9:15 pm - 9:30 pm | Discussion |
| 9:30 pm | Continued informal discussion and wine at the poster session |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | The Legacy of Stanley Miller: Heterotrophic Origins |
| Discussion Leader: Jeffrey Bada (Univ. California, San Diego) |
| 9:00 am - 9:30 am | Jeff Bada (University of California, San Diego) "Stanley Miller: The Father of Prebiotic Chemistry" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:15 am | Antonio Lazcano (UNAM, Mexico City) "Stanley Miller and the Origin of Life" |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | H. James Cleaves (Carnegie Institution) "Prebiotic Synthesis in Neutral Planetary
Atmospheres" |
| 11:30 am - 11:45 am | Discussion |
| 11:45 am - 12:15 pm | Peter Nielsen (Univ. of Copenhagen) "Peptide Nucleic Acids, A Possible Beginning?" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 8:30 pm | Progress towards Synthesizing an Artificial Cell |
| Discussion Leader: Robert Hazen (Carnegie Institution of Washington) |
| 7:30 pm - 8:10 pm | Keynote Speaker: Jack Szostak (Harvard University and Mass General Hospital) |
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:30 pm | Origins and Evolution of Biochemical Homochirality |
| Discussion Leader: Robert Hazen (Carnegie Institution of Washington) |
| 8:30 pm - 9:10 pm | Donna Blackmond (Imperial College London) |
| 9:10 pm - 9:30 pm | Discussion |
| 9:30 pm | Continued informal discussion and wine at the poster session |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | The Legacy of Leslie Orgel: The Case for the RNA World |
| Discussion Leader: John Sutherland (Univ. of Manchester) |
| 9:00 am - 9:30 am | John Sutherland (Univ. of Manchester) "Prebiotic RNA Chemistry" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:15 am | Harry Noller (Univ. of California, Santa Cruz) "Thoughts on the Emergence of the Ribosome from the RNA World" |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Reza Ghadiri (Scripps Research Institute) "Possible Links Between RNA and Amino
Acid/Peptide Chemistry" |
| 11:30 am - 11:45 am | Discussion |
| 11:45 am - 12:15 pm | Ram Krishnamurthy (Scripps Research Institute) "Alternative Heterocycles in the Search for Informational Oligomer Systems" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Reconciling the Metabolism First versus RNA World Debate |
| Discussion Leader: George Fox (University of Houston) |
| 7:30 pm - 8:10 pm | Nigel Goldenfeld (Univ. of Illinois) "What Does the Genetic Code Tell Us About Early Life" |
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:10 pm | Günter von Kiedrowski (Ruhr University Bochum) "Systems Chemistry: Looking for Origins versus the Origin of Life" |
| 9:10 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |