| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | The Oral Microbiome: What have we learned and where are we? |
| Discussion Leader: Michael Curtis (Barts and The London) |
| 7:40 pm - 8:10 pm | Jeffrey L. Ebersole (University of Kentucky)
"GRC on Periodontal Disease: 1981 to the Present" |
| 8:10 pm - 8:40 pm | Jacques Izard (Forsyth Institute)
"Community Membership and Genetic Potential of the Oral Microbiota of the Reference Cohort of the Human Microbiome Project"
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| 8:40 pm - 9:10 pm | Slava Epstein (Northeastern University)
"Cultivation and Domestication of Previously Uncultivated Species from the Human Oral Cavity" |
| 9:10 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Inflammation and Innate Immunity: How the host copes with Chronic microbial challenge! |
| Discussion Leader: Thomas van Dyke (Forsyth Institute) |
| 9:00 am - 9:40 am | George Hajishengalis (Univ. of Louisville)
"Oral Pathogen Exploitation of Innate Recognition as a Function of Age" |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am | Coffee Break |
| 10:30 am - 11:10 am | Anna Dongari-Bagtzoglou (Univ. of Connecticut)
"Oral Epithelial Cells, Candida, and PMN Activation" |
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:10 pm | Aaron Weinberg (Case Western University)
"Ontogeny of Oral Epithelial Antimicrobial Peptides" |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Adaptive Immunity: The Good, the Bad, and the Ugly! |
| Discussion Leader: Panos Papapanou (Columbia Univ.) |
| 7:30 pm - 8:10 pm | Toshihisa Kawai (Forsyth Institute)
"Amelioration of Immune Cell-Mediated Periodontal Disease"
|
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:10 pm | Shannon Wallett (Univ. of Florida)
"Aberrant Immunological Phenotypes/Functions in the Progression of Early-Onset AGP" |
| 9:10 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Osteoimmunology: Inflammation in Oral Tissues and Bone |
| Discussion Leader: Dana Graves (Univ. of Pennsylvania) |
| 9:00 am - 9:40 am | Dana Graves (Univ. of Pennsylvania)
"Mechanisms Through Which Diabetes Affects Soft and Hard Tissue Healing" |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am | Coffee Break |
| 10:30 am - 11:10 am | Keith Kirkwood (Medical Univ. of South Carolina)
"Role of TNFA in Osteoclast-Mediated Bone Loss" |
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:10 pm | Joseph Lorenzo (Univ. of Connecticut)
"Characterization and Regulation of Osteoclast Precursor Cells" |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Osteoimmunology: Inflammation in Oral Tissues and Bone (cont.) |
| Discussion Leader: Dana Graves (Univ. of Pennsylvania) |
| 7:30 pm - 8:10 pm | Jian (Jerry) Feng (Baylor Univ.)
"Molecular Mechanism of Osteocyte Maturation and its Impact on Periodontal Diseases" |
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:10 pm | Gustavo Garlet (Barua Univ., Sao Paulo)
"Regulatory T cells Attenuate Experimental Periodontitis in Mice" |
| 9:10 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Patient Specificity for Disease: Who is at risk and Why? |
| Discussion Leader: Denis Kinane (Univ. of Pennsylvania) |
| 9:00 am - 9:40 am | Thomas Hart (Univ. of Illinois at Chicago)
"Genetic Studies of Human Craniofacial Diseases" |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am | Coffee Break |
| 10:30 am - 11:10 am | Alexandre Vieira (Univ. of Pittsburgh)
"FAM5C Contributes to Aggressive Periodontitis" |
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:10 pm | Deborah Polk (Univ. of Pittsburgh)
"Gene by Behavioral Environment Interactions in Chronic Periodontitis" |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 7:30 pm - 9:30 pm | Periodontal Therapy and Regeneration: Biological and Mechanical |
| Discussion Leader: David Puleo (Univ. of Kentucky) |
| 7:30 pm - 8:10 pm | Paul Krebsbach (Univ. of Michigan)
"Pluripotent Stem Cells: Opening another Avenue for Craniofacial Regeneration" |
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:10 pm | Lyndon Cooper (Univ. of North Carolina)
"Inflammatory Control of Periodontal Regeneration" |
| 9:10 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Periodontal Disease a Public Health Issue: What is the impact on research and potential for diagnostics? |
| Discussion Leader: M. John Novak (Univ. of Kentucky) |
| 9:00 am - 9:40 am | James Beck (Univ. of North Carolina)
"Periodontal Disease and Systemic Health" |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am | Coffee Break |
| 10:30 am - 11:10 am | Philip Kern (Univ. of Kentucky)
"Inflammation in Adipose Tissue and Muscle: Relationship to Insulin Resistance, Diabetes, and Obesity-Related Metabolic Syndrome" |
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:10 pm | Salomon Amar (Boston Univ.)
"Role of Obesity in Infection" |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Periodontal Disease a Public Health Issue: What is the impact on research and potential for diagnostics? (cont.) |
| Discussion Leader: M. John Novak (Univ. of Kentucky) |
| 7:30 pm - 8:10 pm | Maria Febbraio (Cleveland Clinic)
"CD36, Periodontitis & Atherosclerosis" |
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:10 pm | Craig Miller (Univ. of Kentucky)
"Salivary Biomarkers of Periodontal Disease" |
| 9:10 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |