Sunday |
2:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Genotypic Precision Medicine and Phenotypic Personalized Medicine |
| Discussion Leader: Bill Gahl (National Human Genome Research Institute, NIH, USA) |
7:40 pm - 7:55 pm | Introduction by Discussion Leader |
7:55 pm - 8:35 pm | Bruce Gelb (Icahn School of Medicine at Mount Sinai, USA) "Getting Personal: The Path from Congenital Heart Disease Genetics to Better Outcomes" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:25 pm | Wee Joo Chng (Cancer Science Institute of Singapore, National University of Singapore, Singapore) and Edward Kai-Hua Chow (Cancer Science Institute of Singapore, National University of Singapore, Singapore) "Phenotypic Personalized Medicine in Multiple Myeloma" |
9:25 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Personalized/Precision Medicine and Enabling Technologies |
| Discussion Leader: Megan Frisk (Science Translational Medicine, USA) |
9:00 am - 9:15 am | Introduction by Discussion Leader |
9:15 am - 9:55 am | Steven Rosen (City of Hope National Medical Center, USA) "RNA Directed Therapy
(8 Chloro-Adenosine), DNA Directed Therapy (Leflunomide) and Targeting Glucose
Metabolism (Ritonavir Plus Metformin) – Bench to Bedside for AML and Myeloma" |
9:55 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Group Photo / Coffee Break |
10:40 am - 11:20 am | Dean Ho (Weintraub Center for Reconstructive Biotechnology, University of California, Los Angeles, USA) "Phenotypic Personalized Medicine: Actionable Individualization of Patient Therapy" |
11:20 am - 11:35 am | Discussion |
11:35 am - 12:15 pm | Geoffrey Ginsburg (Duke Center for Applied Genomics and Precision Medicine, USA) "Novel Paradigms for the Early Detection of Acute and Chronic Disease" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Personalized Pediatric Medicine |
| Discussion Leader: Katherine Janeway (Dana-Farber Cancer Institute, Harvard University, USA) |
7:30 pm - 7:45 pm | Introduction by Discussion Leader |
7:45 pm - 8:25 pm | Dennis Lo (Chinese University of Hong Kong, Hong Kong SAR China) "Unlocking Hidden Diagnostic Information from Plasma DNA" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:20 pm | Charles Roberts (St. Jude Children's Research Hospital, USA) "SWI/SNF (BAF) Complex Mutations in Cancer: Mechanisms and Therapeutic Vulnerabilities" |
9:20 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Intersection
of Engineering and Medicine |
| Discussion Leader: Hsing Jien Kung (National Health Research Institutes, Taiwan) |
9:00 am - 9:15 am | Introduction by Discussion Leader |
9:15 am - 10:00 am | Yanyi Huang (Peking University, China) "Connection Between the Heterogeneous Phenotypes and Genotypes at Single-Cell Level" |
10:00 am - 10:15 am | Discussion |
10:15 am - 10:30 am | Coffee Break |
10:30 am - 11:15 am | Garry Nolan (Stanford University, USA) "Single Cell Deep Profiling of Cancer and Immunity" |
11:15 am - 11:30 am | Discussion |
11:30 am - 12:15 pm | Pasi Janne (Dana-Farber Cancer Institute, USA) "Strategies to Overcome Drug Resistance in EGFR Mutant Lung Cancer" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
2:00 pm - 4:00 pm | Poster Session |
4:00 pm - 6:00 pm | Individualized Medicine for Cancers |
| Discussion Leader: Richard Weinshilboum (Mayo Medical School, Mayo Clinic, USA) |
4:00 pm - 4:15 pm | Introduction by Discussion Leader |
4:15 pm - 4:55 pm | Xianting Ding (Institute for Personalized Medicine, Shanghai Jiao Tong University, China) "In Vivo Drug Combination Optimization for Colon Cancer Treatment Through a Phenotype Personalized Medicine (PPM) Approach" |
4:55 pm - 5:10 pm | Discussion |
5:10 pm - 5:50 pm | Arjan Griffioen (VU University Medical Center, The Netherlands) and Patrycja Nowak-Sliwinska (University of Geneva, Switzerland) "Identification of Optimal Personalized Combination Therapy for Renal Cell Cancer" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm | Dinner |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Genomics
and Molecular Targets |
| Discussion Leader: Garry Cutting (Johns Hopkins University, USA) |
9:00 am - 9:15 am | Introduction by Discussion Leader |
9:15 am - 9:55 am | Pan-Chyr Yang (National Taiwan University, Taiwan) "Precision Lung Cancer Therapy: EGFR-TK1 and Beyond" |
9:55 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:20 am | C. Thomas Caskey (Baylor College of Medicine, USA) "Metabolomics Adds Function to Genetic Precision Medicine" |
11:20 am - 11:35 am | Discussion |
11:35 am - 12:15 pm | William Mobley (University of California, San Diego, USA) "Defining Genes and Mechanisms Underlying Cognitive Deficits in Down Syndrome" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Personalized Therapies for Blood Disorders |
| Discussion Leader: Qiang Tian (P4 Medicine Institute, USA) |
7:30 pm - 7:45 pm | Introduction by Discussion Leader |
7:45 pm - 8:25 pm | Andrew Feldman (Mayo Clinic Cancer Center, USA) "Individualizing Therapy in Lymphoma" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:20 pm | Karl Tsim (Hong Kong University of Science and Technology, Hong Kong SAR China) and Yi-Kuen Lee (Hong Kong University of Science and Technology, Hong Kong SAR China) "Traditional Chinese Medicine: A Yin-Yang Balance of Personalized Medicine" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Personalized Immunotherapy |
| Discussion Leader: Patrick Tan (Duke-NUS Medical School, Singapore) |
9:00 am - 9:15 am | Introduction by Discussion Leader |
9:15 am - 10:00 am | Yusuke Nakumura (Center for Personalized Therapeutics, University of Chicago, USA) "Cancer Precision Medicine and Neoantigen Vaccine Treatment" |
10:00 am - 10:15 am | Discussion |
10:15 am - 10:30 am | Coffee Break |
10:30 am - 11:15 am | Lieping Chen (Yale University, USA) "The PD-1/PD-L1 Blockade: A New Class of Cancer Immunotherapy" |
11:15 am - 11:30 am | Discussion |
11:30 am - 12:15 pm | Ali Zarrinpar (David Geffen School of Medicine at UCLA, USA) "Patient-Specific Drug Interaction Mapping in Personalized Immunosuppression" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Late-Breaking Topics |
| Discussion Leader: Yiwu He (BGI, China) |
4:00 pm - 4:20 pm | Introduction by Discussion Leader |
4:20 pm - 4:50 pm | Gunaretnam Rajagopal (Janssen R&D, USA) and Zhen Gu (University of North Carolina at Chapel Hill, USA) "Integration of GPM. PPM and Enabling Technologies" |
4:50 pm - 5:00 pm | Discussion |
5:00 pm - 5:30 pm | Navaline Quach (Tecan, USA) and Julia Zhen (Thermo Fisher Scientific, USA) "Industrial Participation and Government Regulatory Process" |
5:30 pm - 5:40 pm | Discussion |
5:40 pm - 6:00 pm | General Discussion |
6:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |