Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: The Tumor Myeloid Microenvironment
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:10 pm
Introduction by Discussion Leader
8:10 pm - 9:10 pm
"Monocytes, Dendritic Cells, and Macrophages – A Migratory Journey"
9:10 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Innate Immunity from a Cancer Perspective
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Tumor-Associated Myeloid Cells: The Good, the Bad, and the Ugly"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Primary Tumor Associated Macrophages Activate Programs of Invasion and Dormancy in Disseminating Tumor Cells"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Post-infectious Microglia: Harnessing Phagocytosis to Protect the Brain"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
" Neutrophils and PMN-MDSC: Two-Faced Janus of Innate Immunity"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Regulation of Neutrophil Recruitment to the Tumor Niche in Breast Cancer"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Outside Influences on Phagocyte Function
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Listeriolysin O Induces Phagosome Stress Response"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"A New Challenge at the Oral Mucosa: Neutrophils Coping with Emerging Oral Pathogens"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Some Wine with Your Meal? PIKfyve Drives Macropinosome/Phagosome Fusion to Aid Digestion"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Elucidating Key Interactions Between Coccidioides and Macrophages"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
The Cytoskeleton and Membrane Trafficking
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Actin and Myosin Cross-Talk During Phagocytosis"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Enhancing Macrophage Phagocytosis of Cancer Cells Targeted with Therapeutic Antibodies"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"How to Build an Efficient Phagosome: Lessons from Pathogens"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"4D Imaging Reveals New Insight into Macropinosome Formation and Closure"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Phagocytes Prevent Invasive Growth of Aspergillus Hyphae in Zebrafish Larvae"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Emerging Phagocyte Influencers
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Neutrophils Cooperate in the Biosynthesis of Lipid Mediators Driving Swarming"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Fate and Functions of Macrophages in the Heart"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Resolvin E4 is activated in Physiologic Hypoxia: Biosynthesis and Actions of the Newest Resolvin"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Role for TL1A in Innate Intestinal Inflammation and Colitis Associated Cancer"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Multisystem Profiling Reveals Phagocyte Responses in Divergent Outcomes to Viral Infection"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Macrophage Reprogramming in Tuberculosis"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Neutrophil Signaling in Autoimmune and Inflammatory Disease Models"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"Metabolic Reprogramming of Neutrophils by Francisella tularensis"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"How Phagocytes Acquired the Capability of Hunting and Removing Pathogens from a Human Body: Lessons Learned from Chemotaxis and Phagocytosis of Dictyostelium discoideum"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Phagocyte-Pathogen Cross-Talk
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Use of Zebrafish to Study Shigella-Phagocyte Interactions"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Playing with Fire: Neutrophils in the Pathogenesis of Neisseria Gonorrhoeae Infection"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"The Expression of Integrin aDß2 (CD11d/CD18) on Neutrophils Promotes Macrophage Migration and Prevents the Development of Endotoxemia and Sepsis"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Training Innate Immunity in Zebrafish Using Shigella"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Inflammasomes and Autophagy
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"IVIg Targets IL-1ß-Expressing Neutrophils in Kawasaki Disease and MIS-C"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Phagosome Resolution Maintains the Degradative Capacity in Phagocytes"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"The Underappreciated Role of Neutrophils as a Source of IL-1a and IL-1ß in Microbial Infections"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"The Neutrophil in Autoinflammation"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Neurorepellent SLIT2 Promotes Host Innate Immune Responses during Bacterial Infection"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Transporters and Environmental Effects on Phagocyte Responses
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Solute Carrier Transporters Modulate Inflammasome Activity by Regulating Autophagy in Dendritic Cells"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Solute Fluxes and the Surveillance of Fluid by Resident Macrophages"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Characterization of Lipid ROS-Mediated Biological Events Coupled with NADPH Oxidases during Ferroptosis in Macrophages"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Nexinhib20 Inhibits Neutrophil Adhesion and ß2 Integrin Activation by Antagonizing Rac-1-GTP Interaction"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure