| SATURDAY |
| 2:00 pm | Check-In Begins |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Innate and adaptive immunity |
| Discussion Leader: Justin Schwartz (University of Iowa) |
| 3:15 pm - 3:30 pm | Sarah Ewald (University of California)
"The activation of TLR9 is coupled to proteolytic processing in the endolysosome as a means of restricting the response to nucleic acids" |
| 3:30 pm - 3:37 pm | Discussion |
| 3:37 pm - 3:52 pm | David Ermert (CHARITEPLATZ 1, Max Planck Institute for Infection Biology, Berlin, Germany)
"Mouse Neutrophil Extracellular Traps" |
| 3:52 pm - 4:00 pm | Discussion |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Effects of pathogens on innate immune cells |
| Discussion Leader: Lynda Stuart (Massachusetts General Hospital) |
| 7:30 pm - 7:50 pm | Anna Sokolovska (Massachusetts General Hospital)
"Caspase-1 activation in response to S. aureus regulates phagosome maturation and acidification" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Csaba Timar (Semmelweis University, Budapest, Hungary)
"Formation of microparticles by neutrophilic granulocytes" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Ramona Mccaffrey (University of Iowa)
"Mechanisms of NADPH oxidase inhibition by Francisella tularensis" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Jia Chen (University of Illinois College of Medicine, Chicago)
"Chemoattractant-induced NADPH oxidase activation" |
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Effects of innate immune cells on pathogens |
| Discussion Leader: Bill Nauseef (University of Iowa) |
| 9:00 am - 9:20 am | David Mason (University of Toronto)
"Receptor-derived signalling controls the clearance of actin during phagocytosis" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Gregory Luerman (University of Louisville)
"Proteomic Analysis of Phosphoproteins Associated with Neutrophil Granule Exocytosis" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Subhankar Mukhopadhyay (Massachusetts General Hospital)
"Innate Immune Activation: A new activation state of macrophages in response to microbes and contributes to inflammatory pathologies" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:15 am | Chengyuk Lee (University of California)
"Single-cell biophysical approach exposes pathway-specific mechanics of phagocytosis" |
| 11:15 am - 11:25 am | Discussion |
| 11:25 am - 11:40 am | Melody Yue Zeng (Indiana University School of Medicine)
"Rac Regulation of NADPH Oxidase in Phagocytic Leukocytes: More to the Story than p67phox" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:05 pm | Amanda M. Jamieson (University of Vienna, Austria)
"Modulation of the innate immune response to bacteria by viral infection" |
| 12:05 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:30 pm | GRS Evaluation |
| (Discuss request for a subsequent GRS; Fill out Evaluation Forms) |
| 12:30 pm | Lunch |
| 1:30 pm - 3:30 pm | Poster Session II |
| 3:30 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |