Novel Insights and Methods Illuminating G Protein and Kinase Signaling Pathways in Health and Disease

This conference is devoted to understanding the mechanisms by which G protein, kinase, and phosphatase signaling pathways dictate physiological responses at the molecular, cellular, and organismal levels. These pathways were first identified for their role in relaying and amplifying extracellular signals into intracellular responses, driving physiological responses necessary for survival. It is now appreciated that these proteins also amplify and regulate signaling events initiated at intracellular sites and which lead to different health-relevant outcomes. Elucidating these molecular mechanisms requires studies at all scales, from individual proteins to whole organisms, and the development of novel tools and techniques. The ability to control and manipulate these pathways holds immense therapeutic promise for treating cancer, cardiovascular disease, neurological disorders, chronic pain, and many conditions. The 2026 conference will continue our long-standing tradition of bringing together leaders in the field with early career investigators to share cutting-edge discoveries and continue to drive this field forward.