| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Regulation of Melatonin Synthesis |
| 7:30 pm - 7:45 pm | Discussion Leader: David Klein (National Institute of Child Health and Human Development) |
| 7:45 pm - 8:20 pm | Michael Menaker (University of Virginia)
"Melatonin synthesis and per1 rhythmicity in the pineal" |
| 8:20 pm - 8:55 pm | Steven Coon (National Institute of Child Health and Human Development)
"Post-translational regulation of AANAT in a stable cell line" |
| 8:55 pm - 9:30 pm | Surajit Ganguly (National Institute of Child Health and Human Development)
"Melatonin Production: Regulation of AANAT by its Binding Partners" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Nonvisual phototransduction |
| 9:00 am - 9:15 am | Discussion Leader: Russell Foster (Imperial College School of Medicine, London) |
| 9:15 am - 9:55 am | Robert Lucas (Imperial College School of Medicine, London)
"The role of novel photoreceptors in non-image forming light responses in mammals" |
| 9:55 am - 10:30 am | Coffee Break |
| 10:30 am - 11:10 am | David Berson (Brown University)
"Phototransduction by ganglion cells of the retinohypothalamic tract" |
| 11:10 am - 11:50 am | Ignacio Provencio (Uniformed Services University of the Health Sciences)
"Melanopsin: Shedding light on photoentrainment?" |
| 11:50 am - 12:30 pm | Russell Van Gelder (Washington University)
"Ocular functions for mammalian cryptochromes" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Signal Transduction I |
| 7:30 pm - 7:45 pm | Discussion Leader: Martin Zatz (National Institute of Mental Health) |
| 7:45 pm - 8:20 pm | Stuart Dryer (University of Houston)
"Mechanisms underlying circadian control of ion channel gating in retinal photoreceptors: A mechanism for daily adjustments in the gain of a sensory system" |
| 8:20 pm - 8:55 pm | King-Wai Yau (Johns Hopkins School of Medicine)
"Study of phototransduction in vertebrate non-rod/non-cone photoreceptors" |
| 8:55 pm - 9:30 pm | P. Michael Iuvone (Emory University School of Medicine)
"Circadian and light-driven regulation of AA-NAT in chicken retina"
|
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Melatonin Actions I (Human) |
| 9:00 am - 9:15 am | Discussion Leader: Debra Skene (University of Surrey, Guildford, UK) |
| 9:15 am - 9:55 am | Kenneth Wright (Brigham & Women's Hospital)
"Entrainment of the Human Biological Clock" |
| 9:55 am - 10:35 am | Josephine Arendt and others (University of Surrey, Guildford, UK)
"Effects of long duration melatonin in humans" |
| 10:35 am - 11:10 am | Coffee Break |
| 11:10 am - 11:50 am | Rebecca Costello (Office of Dietary Supplements, NIH)
"Melatonin as a Dietary Supplement: Facts, Figures and Fancies of the American Public" |
| 11:50 am - 12:30 pm | Steven Hill (Tulane University School of Medicine)
"Regulation of Steroid Hormone Receptor Transcriptional Activity and Gene Expression by Melatonin in Breast Cancer is Mediated through G alph i2 and G apha q proteins" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I (continued) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Regulation of Gene Expression |
| 7:30 pm - 7:45 pm | Discussion Leader: Pierre Voisin (Laboratoire de Neurobiologie Cellulaire, CNRS - Poitiers, France) |
| 7:45 pm - 8:20 pm | Seth Blackshaw (Harvard Medical School)
"Genomic Analysis of Photoreceptor and Pinealocyte-specific Transcription" |
| 8:20 pm - 8:55 pm | Ruben Baler (National Institutes of Mental Health, NIH)
"Decoding the rat AA-NAT gene promoter" |
| 8:55 pm - 9:30 pm | Jennifer Liang (Case Western University)
"Circadian gene regulation in the zebrafish pineal and parapineal organs" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Circadian Mechanisms |
| 9:00 am - 9:15 am | Discussion Leader: Carla Green (University of Virginia) |
| 9:15 am - 9:55 am | Gregory Cahill (University of Houston)
"Clock mechanisms in zebrafish" |
| 9:55 am - 10:35 am | Vincent Cassone (Texas A & M University)
"Clock genes, the SCN and the Neuroendocrine Loop"
|
| 10:35 am - 11:10 am | Coffee Break |
| 11:10 am - 11:50 am | Steven Reppert (University of Massachusetts Medical School)
"Post-translational control of the mammalian circadian clock" |
| 11:50 am - 12:30 pm | Michael Hastings (Cambridge University, U.K.)
"Central and peripheral clock mechanisms in mice"
|
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Photoperiodism |
| 7:30 pm - 7:45 pm | Discussion Leader: Elizabeth Maywood (Cambridge University, U.K.) |
| 7:45 pm - 8:20 pm | Andrew Loudon (University of Manchester, U.K.)
"Photoperiodism, clock genes and refractoriness" |
| 8:20 pm - 8:55 pm | Horacio de la Iglesia (University of Massachusetts)
"SCN as a photoperiodic tissue" |
| 8:55 pm - 9:30 pm | Charlambos Kyriacou (University of Leicester)
"Comparative molecular analysis of circadian systems" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Pineal/Retinal Signal Transduction II |
| 9:00 am - 9:15 am | Discussion Leader: Gianluca Tosini (Morehouse University School of Medicine) |
| 9:15 am - 9:55 am | Yoshitaka Fukada (The University of Tokyo)
"Circadian clock oscillation and its photic regulation in the chicken pineal gland" |
| 9:55 am - 10:35 am | Chiaki Fukahara (Morehouse University School of Medicine)
"Regulation of gene expression in the rat pineal gland" |
| 10:35 am - 11:10 am | Coffee Break |
| 11:10 am - 11:50 am | Anthony Ho (University of Alberta)
"MAPKs in rat pinealocytes" |
| 11:50 am - 12:30 am | Jimo Borjigin (Carnegie Institution of Washington)
"Tri-phasic circadian rhythm of serotonin secretion from the pineal" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II (continued) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Melatonin Action II |
| 7:30 pm - 7:45 pm | Discussion Leader: Margarita Dubocovich (Northwestern University Medical School) |
| 7:45 pm - 8:20 pm | David Hazlerigg (Rowett Research Institute, Scotland, U.K.)
"Photoperiodic effects on circadian gene expression in a melatonin target tissue" |
| 8:20 pm - 8:55 pm | Jörg Stehle (University of Frankfurt, Germany)
"Melatonin - a clock output, a clock input" |
| 8:55 pm - 9:30 pm | Célia R. S. Garcia (University of São Paulo)
"Melatonin synchronizes intraerythrocytic Malaria parasites"
|
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
