Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Plant Metabolic Engineering for Advancing Human Health and Sustainability
7:40 pm - 8:25 pm
"Integrating Network Science and AI: Insights from the Foodome Project"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
"Recombinant Production of Plant Secondary Metabolites and Enzymes for Biotechnological Applications"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Integration of Artificial Intelligence
9:00 am - 9:30 am
"Structure-enabled Enzyme Function Prediction Unveils Elusive Terpenoid Biosynthesis in Archaea"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Boosting Mass Spectrometry-based Metabolomics with Machine-Learning Powered Analogue Search, Substructure Discovery, and Cross-Ion Mode Matching."
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Controllable Protein Design and Engineering with Reinforcement Learning"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Generative Foundation Models Enable Bio-retrosynthesis of Natural Products"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Iridoid Biosynthesis in Asterids"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Innovations in Plant Enzyme Engineering
6:00 pm - 6:30 pm
"Unusual Enzyme Reactions in Natural Product Biosynthesis"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"Remodeling and Molecular Editing of Plant-derived Natural Products with Engineered Metalloenzymes"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Breaking Boundaries: Engineering Plants to Produce Nutrients They Never Evolved to Make"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Harnessing the Therapeutic Potential of Medicinal Plants through Discovery and Bioengineering
9:00 am - 9:30 am
"Ethnobotany as a Tool for Natural Product Drug Discovery"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Novel Chemistry and Enzyme Classes in Medicinal Plants"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Turning Bitter Lupins Sweet - Biosynthesis and Transport of the Lupin Alkaloids"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Specialized Cells for Plant Specialized Metabolism? The Example of Hyperforin and Hyper Cells in St. John’s Wort"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Discovery of Widespread Plant Defense Compounds Against Cross-kingdom Pathogens"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Consideration of Plant-Microbe Interactions for Plant Metabolic Engineering
6:00 pm - 6:30 pm
"High-throughput Approaches for Engineering the Plant Rhizosphere Microbiome"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"Endophytes as Drivers of Bioactive Compound Production in Plants"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Interactions at the Root-Soil Interface: How Commensal Rhizobacteria Influence Plant Immunity and Metabolism"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Plant-Based Foods and Their Relationship to Human Health and Diseases
9:00 am - 9:30 am
"Biology and Chemistry of Plant Molecules in the Diet"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Engineering Tolerance Using Our Understanding of How Human Antibodies Recognize Allergens From Plants"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Pathway and Transport Engineering for Sustainable Production of Plant-Based Protein Food"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"The Periodic Table of Food Initiative: A Comprehensive Standardized Platform for Cataloging the Diversity of Plant Chemistry"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Engineering Plants for Enhanced Nutrition
6:00 pm - 6:30 pm
"Toward Tailored Seeds Amino Acid Biofortification"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"Enhancing Crop Nitrogen Content through Metabolic Engineering of the Serine/Glycine Network"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Apocarotenoid Metabolism Involves Unexpected Cytochrome P450 Reactions"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Plant Engineering for Climate Resilience
9:00 am - 9:30 am
"Synthetic Genetic Circuits for Cell Type-specific Reprogramming of Gene Expression in Plants"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Engineering Rubisco Activase for Crop Thermotolerance"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Interplay Between Conjugated Sterol Metabolism and the Whole Cell Metabolic Status in Tomato"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Strategies to Improve Photosynthetic Carbon Metabolism to Enable Increased Crop Yield"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Plant Defense Through Protein Excretion and mRNA Delivery"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Industrial Applications of Plant Metabolic Engineering
6:00 pm - 6:20 pm
"Brassinosteroid-driven Metabolic Adaptation to Abiotic Stress"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Putting a New Spin on an Old Technology: Using Plant Cell Culture to Make Botanical Ingredients"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Improving Food System Sustainability using SEEDesignTM"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Scientific Publishing in a Time of Accelerated Discovery, Global Shifts, and AI"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure