Saturday
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2:00 pm - 5:00 pm |
Arrival and Check-in
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3:30 pm - 3:45 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
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3:45 pm - 4:30 pm |
Keynote Session: Global Approaches to Determining the Role of Extracellular Proteolysis in Disease
Discussion Leader: Nowah Afangbedji (Howard University, USA)
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3:45 pm - 4:25 pm |
Charles Craik (University of California, San Francisco, USA)
"Global Approaches to Determining the Role of Extracellular Proteolysis in Disease"
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4:25 pm - 4:30 pm |
Discussion
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4:30 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Roles and Therapeutic Implications of Extracellular Proteases in Cancer Biology and Neurobiology
Discussion Leader: Umar Ali (Illawarra Health and Medical Research Institute, University of Wollongong, Australia)
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7:30 pm - 7:45 pm |
Ariel Diaz (Emory University, USA)
"Urokinase Regulates N-Cadherin-Mediated Synaptic Formation in the Ischemic Brain"
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7:45 pm - 7:50 pm |
Discussion
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7:50 pm - 8:05 pm |
Joachim Mertens (University of Antwerp, Belgium)
"Selective Inhibition of CPU Reduces Downstream Microvascular Thrombosis in an Experimental Rat Stroke Model"
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8:05 pm - 8:10 pm |
Discussion
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8:10 pm - 8:25 pm |
Adam Miszta (Synapse Research Institute, The Netherlands)
"A Novel Plasmin Generation Assay to Monitor Pharmacodynamic Effects of Tranexamic Acid"
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8:25 pm - 8:30 pm |
Discussion
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8:30 pm - 8:45 pm |
Benjamin Buckley (University of Wollongong, Australia)
"Developing of Potent Antimetastatic Candidates from the Oral Diuretic Amiloride"
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8:45 pm - 8:50 pm |
Discussion
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8:50 pm - 9:05 pm |
Gabriel Vieira (University of Sao Paulo, Brazil)
"Proteolytic Profile of Pre-Malignant and Malignant Cervix Lesions"
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9:05 pm - 9:10 pm |
Discussion
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9:10 pm - 9:25 pm |
Yi Yang (University of North Carolina at Chapel Hill, USA)
"Thrombin Signaling Promotes Pancreatic Adenocarcinoma Through PAR-1-Dependent Immune Evasion"
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9:25 pm - 9:30 pm |
Discussion
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Sunday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 11:00 am |
Roles of Extracellular Proteases Vascular Biology and Infectious Diseases
Discussion Leader: Dante Disharoon (Colorado School of Mines, USA)
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9:00 am - 9:15 am |
Allison Arai (University of Maryland School of Medicine, USA)
"De-Regulation of MMP-1 Levels in a Young Patient with Abdominal Aortic Aneurysms"
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9:15 am - 9:20 am |
Discussion
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9:20 am - 9:35 am |
Rene Girard (University of Texas Health Science Center at Tyler, USA)
"Anything Could Happen: Development Time Affects PAI-1 and Cytokine Levels in the Rabbit Empyema Model"
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9:35 am - 9:40 am |
Discussion
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9:40 am - 9:55 am |
Yetunde Ayinuola (University of Notre Dame, USA)
"Pattern D Streptococcus pyogenes, Strain AP53 Maintains Its Plasminogen-Binding Ability upon Deletion of Sortase-A but Lacks Other Virulence Determinants Needed for Survival in Host Cells"
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9:55 am - 10:00 am |
Discussion
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10:00 am - 10:15 am |
Oscar Negron (University of North Carolina at Chapel Hill, USA)
"A Human Fibrinogen Variant with Impaired Staphylococcus aureus Binding Function Promotes Host Survival During Septicemia in Mice"
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10:15 am - 10:20 am |
Discussion
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10:20 am - 10:35 am |
Henry Vu (University of Notre Dame, USA)
"Real-Time Dynamics of Wound Healing with Group A Streptococcus and Plasminogen"
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10:35 am - 10:40 am |
Discussion
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10:40 am - 10:55 am |
Collin Tran (National Institutes of Health, USA)
"Firin Is a Critical Regulator of Oral Mucosal Immunopathology"
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10:55 am - 11:00 am |
Discussion
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11:00 am - 12:30 pm |
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 2:30 pm |
Mentorship Component: Rigor and Reproducibility in the Study of Extracellular Proteases
Discussion Leader: Lakmali Silva (National Institute of Dental and Craniofacial Research, NIH, USA)
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1:30 pm - 2:30 pm |
Panel Discussion
Rigor and Reproducibility in the Study of Extracellular Proteases
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Erin Norris (The Rockefeller University, USA)
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Stella Tsirka (Stony Brook University, USA)
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Charles Craik (University of California, San Francisco, USA)
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2:30 pm - 3:00 pm |
Evaluation Period
Fill in GRS Evaluation Forms
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3:00 pm |
Seminar Concludes
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