Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Drugs as Materials
7:40 pm - 8:20 pm
"The Formulator's Fab Five: Form, Function,
Formulation, Fit and Foresight"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Nano Particulate RNA Delivery and In Vivo Genome Editing"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Advanced
Characterization Techniques for Small Molecules
9:00 am - 9:40 am
"Imaging Drug
Formulation with Stimulated Raman Scattering Microscopy"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
"Sensitizing Solid-State NMR Spectroscopy for
the Characterization of Pure and Formulated APIs"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
"Applications of Terahertz Spectroscopy in Pharmaceutical Development"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Amorphous
Pharmaceuticals: New Insights into Predicting Stability and Designing Formulations
7:30 pm - 8:00 pm
"The Molecular Factors Relevant for the Physical
Stability of Amorphous Drugs"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"The
Impact of Specific Surface Area (SSA) on Stability of Amorphous Pharmaceuticals"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Amorphous
Solid Dispersion of Poorly Soluble Drugs: Understanding the Enhanced Dissolution
and Absorption"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Novel
Manufacturing Methods
9:00 am - 9:40 am
"Protein and Small Molecule Delivery from Poly(ester Urea)s"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
"PRINT Particle Engineering for Drug Delivery Applications"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
"Printing Soft Matter in Three Dimensions"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Advances
in the Delivery of Bio-Therapeutics
7:30 pm - 8:00 pm
"Assembly of Therapeutic Proteins into Structures that Enable Their Delivery"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Hydrogel-Based Drug Delivery: Preprogrammed to On-Demand"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Dissecting Lipid Nanoparticle-Based mRNA Delivery"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Advanced Methods in the Biophysical Characterization of Large Molecules
9:00 am - 9:40 am
"The Use of Biophysical Characterization During Product Development"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
"Mechanisms of the Membrane Insertion of pHLIP Induced by Residue-Specific Protonation and Its Applications in Drug Delivery"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
"Emerging
Automated Technologies for Miniaturized Formulation Development"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Predictive Sciences in Form and Formulation Development
7:30 pm - 8:00 pm
"In Silico Solid-State Chemistry Applications in Pharmaceutical Industry"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Quantitative Biopharmaceutics: Use of Modeling and Simulation to Inform API and Formulation Decisions"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Accurate and Affordable Calculation of Polymorphic Lattice (Free) Energies: Are We There Yet?"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Advances in the Delivery of Small Molecules
9:00 am - 9:40 am
"Tuning Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) Towards the Desired Drug Absorption Profile"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
"Development of Polymer-Based Sustained Release Formulations for Protein and Peptide Delivery"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
"Carrier-Free Delivery of Anti-Cancer Drugs"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mechanochemistry:
From Co-Crystals to Peptides
7:30 pm - 8:00 pm
"Mechanochemistry for Organic Synthesis: Expect the Unexpected"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Mechanochemistry as a Solid Form Screening Approach in Drug Development"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"May the Mechanical Force Be with You: The Case of Peptides and Organometallics"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure