Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Advances in the Understanding of Drug Delivery Systems
7:40 pm - 8:20 pm
"Borrowing from Regenerative Medicine: 3D Cell Culture for Drug Screening"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Phase Behavior of Amorphous Solid Dispersions"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Advanced Characterization Tools: Structure and Dynamics of Materials
9:00 am - 9:45 am
"Why THz Dynamics Matter for Lyo Product Stability, and How They Can Be of Use"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Group Photo / Coffee Break
10:30 am - 11:15 am
"Laser-Induced Breakdown Spectroscopy (LIBS) Hyperspectral Imaging with Multivariate Analysis for Pharmaceutical Investigations"
11:15 am - 11:30 am
Discussion
11:30 am - 12:15 pm
"MicroED: Conception, Practice and Future Opportunities"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cell and Gene-Based Therapies
7:30 pm - 8:00 pm
"Immunometabolic Reprogramming of Natural Killer Cells for Immunotherapies of Solid Tumors"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Controlled Polymer Synthesis and Assembly to Promote Drug Delivery and Cellular Gene Editing"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Engineering Lipid Nanoparticles for the First Approved RNAi Therapeutic"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Novel Manufacturing Techniques for Small and Large Molecules
9:00 am - 9:45 am
"Formulating Drug Products Using Structured Microcarriers"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:15 am
"3D Printing of Solid Oral Dosage Forms"
11:15 am - 11:30 am
Discussion
11:30 am - 12:15 pm
"Encapsulation and Release of Peptides and Biologics at Higher Loadings"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 8:00 pm
"Crystal Structure Prediction: A First Step Towards Digital Drug Product Design"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Formulation Starts in Discovery"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Intelligent Cloud-Based Algorithms for Pharmaceutical Sciences"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Colloids and Interface Science in Pharmaceutical Research
9:00 am - 9:45 am
"The Influence of the Solid-Liquid Interface on Drug Formulation, Quality and Stability"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:15 am
"The Activity of Inactive Ingredients and the Role of Colloidal Aggregation in Modulating Drug Behavior"
11:15 am - 11:30 am
Discussion
11:30 am - 12:15 pm
"Design of Structured Microparticles Using Spray Drying"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Advanced Characterization Tools: Microstructure of Materials
7:30 pm - 8:00 pm
"Quantitative Microscopy of Pharmaceutical Formulation"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Image-Based Drug Micro-Structure Characterization and Release Dynamics Optimization"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Cryo-Electron Microscopy: A Platform for Vaccine Design Validation"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Intracellular Drug Delivery of Macromolecules
9:00 am - 9:45 am
"Extracellular Vesicles as Advance Forces in Glioblastoma"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:15 am
"Engineering Intracellular Drug Therapies for Small Molecules and Protein Therapeutics"
11:15 am - 11:30 am
Discussion
11:30 am - 12:15 pm
"Intracellular Trafficking of RNA Loaded Lipid Nano-Particles"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Crystallization of Molecules
5:30 pm - 6:00 pm
"Medicinal Mechanochemistry: Developing Cleaner, Safer and More Efficient Routes to API Solids"
6:00 pm - 6:10 pm
Discussion
6:10 pm - 6:40 pm
"Protein Crystallization in the Age of Biotherapeutics"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
"Coupled Preferential Crystallization as a Simple, Scalable Technique to Access Chiral Molecules"
7:20 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure