Gordon Research Conferences
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Conference Program
 
Tropical Infectious Diseases
Challenges, Opportunities and Successes
March 8-13, 2015
Hotel Galvez
Galveston, TX
Chair:
Serap Aksoy

Vice Chair:
Jesus Valenzuela

Application Deadline
Applications are no longer being accepted for this meeting. If you have been instructed to apply by the Conference Chair, please contact Holly Tobin for further instructions.
Related Meeting Information
The Tropical Infectious Diseases Gordon Research Conference will be held in conjunction with the Tropical Infectious Diseases Gordon Research Seminar. Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Please refer to the Tropical Infectious Diseases GRS web page for more information.

The 2015 Gordon Research Conference on "Tropical Infectious Diseases: Challenges, Opportunities and Successes", will present cutting edge research on the most prevalent and medically important tropical infectious diseases (TIDs). Similar to earlier GRCs, the intent of this conference is to gather a multidisciplinary community of scientists for the purpose of discussing basic and field-based research with translational implications in TIDs. The conference will particularly emphasize participation by junior and senior scientists from disease endemic countries.

The 2015 Conference will include sessions that focus on important TIDs, such as malaria, arboviral diseases and poverty-associated neglected tropical diseases (NTDs). In addition, thematic sessions, including management of parasite drug and vector insecticide resistance, status of vaccine development efforts for TIDs, advancements in vector biology for TID control and diseases targeted for elimination by 2020, will be highlighted. For each session, invited speakers who are at the forefront of their respective fields will discuss how progress made at the bench is being translated to actions in the field. Speakers will emphasize interventions based on treatment, vaccination, or interruption of transmission cycles in vectors or reservoir hosts.

An important goal of the Gordon Conference is to attract junior scientists and graduate students (including those from disease endemic countries) to present their work and exchange ideas with leaders in the field. As such, new to this year’s conference will be a "Tropical Infectious Diseases" Gordon Research Seminar (GRS) that will take place prior to the main GRC. The GRS will serve as a platform that allows selected student and postdoctoral researchers to give oral presentations. Additionally, at the GRS junior participants will have the opportunity to present at a poster session and network with other conference attendees.

Both conferences will be held in a historic seaside hotel in Galveston, Texas. This environment offers relaxing beaches and one of the highest concentrations of well-preserved Victorian architecture in the country. Presentations of cutting edge research, along with programmed discussion sessions and opportunities for informal gatherings in the afternoons and evenings, will serve to greatly enrich the community of multidisciplinary and international scientists that work on TIDs.


Contributors

Sunday
4:00 pm - 8:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKeynote Session: Malaria Control
Discussion Leader: Serap Aksoy (Yale University School of Medicine)
7:40 pm - 8:20 pmKeynote: Terrie Taylor (Michigan State University)
"The Pathogenesis of Fatal Cerebral Malaria: Updates from the Field"
8:20 pm - 8:35 pmDiscussion
8:35 pm - 9:20 pmKeynote: Dyann Wirth (Harvard School of Public Health)
"Harnessing Genomics for Malaria Elimination and Eradication"
9:20 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmChallenges for Malaria Control
Discussion Leaders: Photini Sinnis (Johns Hopkins Bloomberg School of Public Health) and Stefanie Trop (Johns Hopkins Bloomberg School of Public Health)
9:00 am - 9:25 amMaria Mota (Institute of Molecular Medicine, Portugal)
"Malaria Biology"
9:25 am - 9:30 amDiscussion
9:30 am - 9:55 amJane Carlton (New York University)
"Global Genetic Diversity of Plasmodium vivax, with a Special Emphasis on India"
9:55 am - 10:00 amDiscussion
10:00 am - 10:25 amChristopher Plowe (HHMI / University of Maryland)
"Applying Genomics to Malaria Elimination"
10:25 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:15 amPhotini Sinnis (Johns Hopkins Bloomberg School of Public Health)
"The Ins and Outs of Plasmodium Sporozoites at the Dermal Inoculation Site"
11:15 am - 11:20 amDiscussion
11:20 am - 11:35 amSelected from Poster Abstracts: Marcelo Jacobs-Lorena (Johns Hopkins School of Public Health)
"CD68 is a Major Determinant for Malaria Sporozoite Liver Infection"
11:35 am - 11:40 amDiscussion
11:40 am - 11:55 amSelected from Poster Abstracts: Amanda Maestre (University of Antioquia, Colombia)
"Placental Infection by P. vivax or P. falciparum Associates with Increased Inflammation; Apoptosis; Hypoxia and Tissue Damage, in Women from Northwest Colombia"
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:30 pmShort Talks Selected from Poster Abstracts
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmDrug and Insecticide Resistance Management for Malaria Control
Discussion Leaders: Philip Rosenthal (University of California, San Francisco) and Sally Warring (New York University)
7:30 pm - 7:55 pmRick Fairhurst (National Institutes of Health)
"Artemisinin Resistance Mechanism"
7:55 pm - 8:00 pmDiscussion
8:00 pm - 8:25 pmPhilip Rosenthal (University of California, San Francisco)
"Resistance to ACT Components in Africa"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:55 pmHilary Ranson (Liverpool School of Tropical Medicine, United Kingdom)
"Insecticide Resistance in Mosquitoes and Its Implications for Malaria Elimination"
8:55 pm - 9:00 pmDiscussion
9:00 pm - 9:10 pmSelected from Poster Abstracts: Cecilia Engdahl (Umeå University, Sweden)
"Combating Mosquito-Borne Infectious Diseases by Rational Design of Selective Insecticides"
9:10 pm - 9:15 pmDiscussion
9:15 pm - 9:25 pmSelected from Poster Abstracts: Christopher Goodman (University of Melbourne, Australia)
"Is Atovaquone Resistance Transmissible?"
9:25 pm - 9:30 pmDiscussion
Tuesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmDengue and Chikungunya Control
Discussion Leaders: Scott Weaver (University of Texas Medical Branch) and Victor Carpio (University of Texas Medical Branch)
9:00 am - 9:25 amScott Weaver (University of Texas Medical Branch)
"Chikungunya Virus Emergence: The Perfect Storm of Vector Invasion and Viral Adaptation"
9:25 am - 9:30 amDiscussion
9:30 am - 9:55 amPattamaporn Kittayapong (Mahidol University, Thailand)
"Integrate Surveillance and Control of Dengue and Chikungunya in Southeast Asia"
9:55 am - 10:00 amDiscussion
10:00 am - 10:25 amNikos Vasilakis (University of Texas Medical Branch)
"DENV-5: Ecology, Evolution and Implications for Vaccine Development and Diagnostics"
10:25 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:25 amLuciano Moreira (Rene Rachou Institute - Fiocruz, Minas Gerais, Brazil)
"Wolbachia Symbiont Mediated Dengue Transmission Control"
11:25 am - 11:30 amDiscussion
11:30 am - 11:55 amAlan Rothman (University of Rhode Island)
"Immune Responses and Immunopathology of Dengue and Implications for Vaccine Development"
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:05 pmSelected from Poster Abstracts: Tonya Colpitts (Tulane School of Public Health & Tropical Medicine)
"The Role of Immature Dengue Virus Particles During Infection of the Mosquito Vector"
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:15 pmSelected from Poster Abstracts: Sujatha Sunil (Inter. Ctr for Genetic Engineering and Biotech., India)
"Chikungunya Virus Encoded Viral Suppressors of RNAi"
12:15 pm - 12:20 pmDiscussion
12:20 pm - 12:25 pmSelected from Poster Abstracts: April Clayton (National Institutes of Health / NIAID)
"Factors that Modulate the Structural Dynamics (Viral 'Breathing') of Flaviviruse"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmChallenges for Vaccine Development and Efficacy for Tropical Infectious Diseases
Discussion Leaders: Alan Rothman (University of Rhode Island) and Astrid Erber (University of Oxford, United Kingdom)
7:30 pm - 7:55 pmSteven Reed (Infectious Disease Research Institute)
"Prospects for Leishmania Vaccines"
7:55 pm - 8:00 pmDiscussion
8:00 pm - 8:25 pmAfzal Siddiqui (Texas Tech University School of Medicine)
"Update on Schistosomiasis Vaccines"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:55 pmLenny Moise (University of Rhode Island)
"Immunoinformatics: New Platforms for Vaccine Target Discovery"
8:55 pm - 9:00 pmDiscussion
9:00 pm - 9:10 pmSelected from Poster Abstracts: Diego Espinosa (Johns Hopkins School of Public Health)
"Antibodies Targeting a Functional Domain in CSP Strongly Inhibit Infectivity of Malaria Sporozoites"
9:10 pm - 9:15 pmDiscussion
9:15 pm - 9:25 pmSelected from Poster Abstracts: Elsio Wunder (Yale School of Public Health)
"An Attenuated Vaccine Model for Acquired-Immune Cross-Protection in Leptospirosis"
9:25 pm - 9:30 pmDiscussion
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmOpportunities in Vector Biology for Control of Tropical Infectious Diseases
Discussion Leaders: Nora Besansky (University of Notre Dame) and Jose Ramirez (National Institutes of Health)
9:00 am - 9:25 amAbdoulaye Diabate (IRSS / Centre Muraz, Burkina Faso)
"Mosquito Swarming Behaviour in the Perspectives of Malaria Control"
9:25 am - 9:30 amDiscussion
9:30 am - 9:55 amCarolina Barillas Mury (National Institutes of Health / NIAID)
"Mosquito Immunity and Global Malaria Transmission"
9:55 am - 10:00 amDiscussion
10:00 am - 10:25 amRebecca Rico Hesse (Baylor College of Medicine)
"Dengue Virus Virulence and Influence of Mosquito Saliva"
10:25 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:25 amMike Lehane (Liverpool School of Tropical Medicine, United Kingdom)
"The Control of Sleeping Sickness: Pushing the Reset Button"
11:25 am - 11:30 amDiscussion
11:30 am - 11:55 amAnandasankar Ray (University of California, Riverside)
"Targeting Vector Olfaction for Disease Control"
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:05 pmSelected from Poster Abstracts: David P Tchouassi (Internat'l Centre of Insect Physiology and Ecology, Kenya)
"Insights into the Epidemiology of Rift Valley Fever from Mosquito Genetics"
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:15 pmSelected from Poster Abstracts: Raúl Saraiva (Johns Hopkins Bloomberg School of Public Health)
"Fighting Bugs with Bugs: Anti-Plasmodium Mechanisms by the Mosquito Midgut Microbiota"
12:15 pm - 12:20 pmDiscussion
12:20 pm - 12:25 pmSelected from Poster Abstracts: Gabriel Ribeiro (Oswaldo Cruz Foundation, Brazil)
"Does Wolbachia Dissemination in Natural Aedes aegypti Populations Affect Its Biology and Interactions with Other Organisms?"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmNeglected Tropical Diseases and Disease Emergence and Control
Discussion Leaders: Albert Ko (Yale School of Public Health) and Janet Lindow (Yale University)
7:30 pm - 7:55 pmAlbert Ko (Yale School of Public Health)
"Urban Slum Health and Tropical Diseases"
7:55 pm - 8:00 pmDiscussion
8:00 pm - 8:25 pmEric Dumonteil (Autonomous University of Yucatan, Mexico)
"Chagas Disease Emergence in the Americas"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:55 pmGrace Murilla (Biotechnology Research Institute, Kalro, Kenya)
"Sustainable Control of HAT in East Africa"
8:55 pm - 9:00 pmDiscussion
9:00 pm - 9:25 pmJean-Pierre Paccaud (Drugs Neglected Diseases Initiative, Switzerland)
"New Approaches and Lessons Learned in Drug Discovery for Kinetoplastid Diseases"
9:25 pm - 9:30 pmDiscussion
Thursday
7:30 am - 8:30 amBreakfast
8:30 am - 9:00 amBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pmTropical Diseases Targeted for Elimination
Discussion Leaders: Peter Hotez (Baylor Medical College) and Reuben Larbi (Yale University)
9:00 am - 9:25 amCharles King (Case Western Reserve University)
"Modern Schistosomiasis Control and the Move Towards Elimination"
9:25 am - 9:30 amDiscussion
9:30 am - 9:55 amKingsley Asiedu (World Health Organization, Switzerland)
"Yaws Eradication Program"
9:55 am - 10:00 amDiscussion
10:00 am - 10:25 amThomas Lietman (University of California, San Francisco)
"Will the Last Case of Trachoma Please Stand Up?"
10:25 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:10 amSelected from Poster Abstracts: Kingsley Badu (Noguchi Memorial Institute for Medical Research, Ghana)
"Entomological Assessments of the Transmission of Onchocerca volvulus by Simulium sanctipauli Within the Forest Zone of Ghana: Intermittent Disappearance of the Vector?"
11:10 am - 11:15 amDiscussion
11:15 am - 11:25 amSelected from Poster Abstracts: Ryan Boyko (Yale University)
"Mechanical Transmission of Human Hookworm by Domestic Animals"
11:25 am - 11:30 amDiscussion
11:30 am - 11:55 amUwemedimo Ekpo (Federal University of Agriculture, Nigeria)
"Scientific Capacity Building in Disease Endemic Countries for Sustainable Control of NTDs"
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:25 pmJulie Jacobson (Bill and Melinda Gates Foundation)
"Elimination and Eradication of NTDs: Learning from the Past and Looking to the Future"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmKeynote Session: Prospects for Tropical Infectious Disease Control
Discussion Leader: Serap Aksoy (Yale University School of Medicine)
7:30 pm - 8:15 pmKeynote: David Sacks (National Institutes of Health)
"Influence of Vector Transmission on Immunity to Parasites"
8:15 pm - 8:30 pmDiscussion
8:30 pm - 9:15 pmKeynote: Peter Hotez (Baylor Medical College)
"NTDs, Blue Marble Health, and the Antipoverty Vaccines"
9:15 pm - 9:30 pmDiscussion
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Funding for this conference was made possible [in part] by 1 R13 AI115832-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

 
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