Gordon Research Conferences
Meeting Details

Cellulosomes, Cellulases & Other Carbohydrate Modifying Enzymes (GRS)
Gordon Research Seminar

A New Era of Research on Carbohydrate-Active Enzymes: Their Reaction Mechanisms and Evolution
Note: This conference is currently known as "Cellulases & Other Carbohydrate-Active Enzymes (GRS)".


August 1-2, 2015


Proctor Academy
Andover, NH


Lauren S. McKee

Meeting Description

The Gordon Research Seminar on Cellulosomes, Cellulases & Other Carbohydrate Modifying Enzymes is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is to present cutting-edge research on the enzymatic degradation of cellulose and other plant cell wall components, featuring contributions on a range of topics including the enzymology related to biosynthesis and biodegradation of plant polysaccharides, metagenomic approaches for the study of cell wall-degrading organisms, structure-function relationships in Carbohydrate-Active enzymes, as well as advances in applications of these enzymes in the biofuel/biorefinery contexts. There will be academic mentors from a variety of diverse backgrounds in attendance at the meeting, in order to encourage the young scientist attendees to actively contribute to the attached GRC, where discussion of new results is key.

Related Meeting

This GRS was held in conjunction with the "Cellulosomes, Cellulases & Other Carbohydrate Modifying Enzymes" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.


Final Meeting Program

2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmEnzymatic Synthesis and Modification of Complex Carbohydrates
Discussion Leader: Wade Abbott (Agriculture and Agrifood Canada, Canada)
3:45 pm - 3:50 pmOpening Remarks
3:50 pm - 4:05 pmElzbieta Rzeszutek (Royal Institute of Technology (KTH), Sweden)
"Expression and Characterisation of Chitin Synthases from the Oomycete Saprolegnia parasitica"
4:05 pm - 4:10 pmDiscussion
4:10 pm - 4:25 pmDavid Albesa-Jove (Unidad de Biofísica, Spain)
"Structural Basis of Chitin Oligosaccharide Deacetylation"
4:25 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmUnderstanding and Engineering the Structure and Function of Carbohydrate Active Enzymes
Discussion Leaders: Zarah Forsberg (Norwegian University of Life Sciences, Norway) and Kiyohiko Igarashi (University of Tokyo, Japan)
7:30 pm - 7:50 pmSophanit Mekasha (Norwegian University of Life Sciences, Norway)
"Structural and Functional Characterization of a Chitin-Active Bi-Catalytic Lytic Polysaccharide Monooxygenase/Glycoside Hydrolase from Jonesia denitrificans"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmSuvamay Jana (University of Kentucky, USA)
"The Relationship of Glycoside Hydrolase Ligand Binding Free Energy to Processive Ability"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmMikako Tachioka (The University of Tokyo, Japan)
"Crystallization of a GH6 Cellobiohydrolase in Microgravity and Structure Determination at 0.85 Angstrom Resolution"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmBastien Bissaro (Norwegian University of Life Sciences (NMBU), Norway)
"Molecular Design of Non-Leloir Furanose-Transferring Enzymes from an α-L-Arabinofuranosidase: A Rationale for the Engineering of Evolved Transglycosylases"
9:20 pm - 9:30 pmDiscussion
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amComplex Systems for Carbohydrate Degradation
Discussion Leader: Nicole Koropatkin (University of Michigan Medical School, USA)
9:00 am - 9:20 amCasper Wilkens (Technical University of Denmark, Denmark)
"The Xylolytic Capacity of the Microbial Consortium in a Thermophilic Anaerobic Digester Fed with Wastewater Surplus Sludge"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amJulie Ravachol (CNRS, France)
"Xyloglucan Utilisation by Ruminiclostridium cellulolyticum"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amDarrell Cockburn (University of Michigan, USA)
"The Amylolytic Systems of Eubacterium rectale and Ruminococcus bromii Rely on Uniquely Adapted Enzymes"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amJulie Grondin (Agriculture and Agri-Food Canada, Canada)
"Carbohydrate Recognition by Multi-Modular Glycoside Hydrolases in the Opportunistic Pathogen Clostridium perfringens"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmProtein-Protein Interactions in the Cellulosome
Discussion Leader: Lior Artzi (Weizmann Institute of Science, Israel)
1:30 pm - 1:50 pmPedro Bule (CIISA - Faculdade de Medicina Veterinária - Universidade de Lisboa, Portugal)
"Structural Determinants of Cohesin-Dockerin Specificity Highlight the Complexity of Ruminococcus flavefaciens Cellulosomes"
1:50 pm - 2:00 pmDiscussion
2:00 pm - 2:20 pmKlara Malinowska (Ludwig-Maximilians-Universität München, Germany)
"Force Propagation Through Ultrastable Cellulosome-Adhesion Complex"
2:20 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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