Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Chemical and Biochemical Tools for Glycosaminoglycan Analysis and Synthesis
7:40 pm - 8:00 pm
"Hyaluronan Biosynthesis: Engineering Polymer Length and Composition"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Targeting Aberrant Glycosylation for Cancer Immunotherapy"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Integrative Proteomic Approaches for In-Depth Characterization of Proteoglycan Remodeling in Human Thoracic Aorta"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
Short Talk Selected from Poster Abstracts
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
New Approach to Analyze Glycosaminoglycan and Protein Interactions
9:00 am - 9:20 am
"Decoding the Sequence Specificity of Glycosaminoglycans to Target HS-Binding Proteins"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Differential Affinity of Chemokines for Heparan Sulfate Underlies Unique Roles in Lymphocyte- and Progenitor-Cell Homing and Retention"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Sequencing Glycosaminoglycans and Glycoconjugates with Ion-Ion Reactions"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
Short Talk Selected from Poster Abstracts
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Enzymatic Synthesis of Heparan Sulfate Polymers and Their Defects: Illuminating Human Multiple Exostoses"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glycosaminoglycans as Therapeutic Targets
7:30 pm - 8:00 pm
"A Never-Ending Love Affair with Proteoglycans"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Short Talk Selected from Poster Abstracts
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Role of Hyaluronan Metabolism in Cell Biology"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Insights on the Roles of Glycosaminoglycans in Muscular and Skeletal Diseases
9:00 am - 9:20 am
"Heparan Sulfate Deficiency and the Genesis of Osteochondromas in a Pediatric Congenital Skeletal Disorder"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Gatekeeping Role of Heparan Sulfate in Macrophage Activity Versus Osteoclast Differentiation"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Targeting Heparan Sulfate-Protease Interactions in Skeletal Diseases"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
Short Talk Selected from Poster Abstracts
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
"The Emerging Role of Syndecan in Intervertebral Disc Health and Disease"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Functions of Glycosaminoglycans in Neurobiology and Neurodegenerative Diseases-1
7:30 pm - 7:50 pm
"Rewriting the Hypothalamic Matrix to Treat Metabolic Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Short Talk Selected from Poster Abstracts
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Glycans Make Synapses Sweet: Uncovering Heparan Sulfate’s Molecular Functions at Synapses"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Emerging Role of Oligodendroglial ADAMTS4 Is Adult Brain Structural Plasticity"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Functions of Glycosaminoglycans in Neurobiology and Neurodegenerative Diseases-2
9:00 am - 9:20 am
"Heparan Sulfate Proteoglycan: A Multifaceted Regulator of Amyloid‑β in the Brain"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Controlled Delivery of Decorin via Hyaluronan Microgels Promotes Scarless Vocal Fold Repair"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Proteoglycan Interactions in Protective Alzheimer’s Gene Variants"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Brain Extracellular Matrix in Neurodegeneration: Friend or Foe?"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glycosaminoglycans in Human Diseases
7:30 pm - 7:50 pm
General Discussion
7:50 pm - 8:10 pm
"Age-Related Endothelial Glycocalyx Fragility During Sepsis"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"A Threat-Agnostic Role of RHAMM in NLRP3 Inflammasome Activation"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
"Hyaluronic Acid Depletion Remodels the Tumor Microenvironment and Improves Preclinical Outcomes in Solid Tumor Models"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
"A Pivotal Role for Glycans in the Fold, Transit, and Toxicity of Prions"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Glycosaminoglycans in Development, Endothelial Functions and Cancers
9:00 am - 9:20 am
"Uncovering and Targeting Syndecan-1 in Pancreatic Cancer: Discovery, Mechanism, and Therapeutic Innovation"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Glycosaminoglycans in Regeneration Termination"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Distinguishing Hyaluronan Receptors via Combinatorial Synthesis of a Hyaluronan Based Polysaccharide Library"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Proteoglycans Shaping the Lens Injury Response: From Regenerative Repair to Fibrotic Outcomes"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"A Mechano-Transduction Feedback Loop via Hyaluronate-ECM Shapes Inner Ear Canals"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Roles of Glycosaminoglycans in Infectious Diseases
7:30 pm - 7:45 pm
Closing Remarks
7:45 pm - 8:05 pm
"Manipulating Neutrophil Function in the Infected Lung: Tale of Two Cell Surface HSPGs"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Short Talk Selected from Poster Abstracts
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"From Matrix to Microthrombi: Hyaluronan-Platelet Interactions in Inflammatory Disease"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure