|2:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||Keynote Speaker|
|3:45 pm - 4:15 pm ||Pat Limbach (University of Cincinnati)|
"RNA spell checking: Approaches for identifying editing and modification sites"
|4:15 pm - 4:30 pm ||Discussion|
|4:30 pm - 6:00 pm||Poster Session I|
|7:30 pm - 9:30 pm||Biological roles of editing and modification|
|Discussion Leaders: Ashani Kuttan (University of Utah) and Gilad Silberberg (Stockholm University)|
|7:30 pm - 7:45 pm ||Bryan Warf (University of Utah)|
"ADARs affect small RNA biogenesis in C. elegans"
|7:45 pm - 7:50 pm ||Discussion|
|7:50 pm - 8:05 pm ||Liu Yang (Institute for Nutritional Sciences, Shanghai)|
"The cellular function and regulation of RNA editing enzyme ADAR2 in pancreatic beta-cells"
|8:05 pm - 8:10 pm ||Discussion|
|8:10 pm - 8:25 pm ||Ylva Ekdahl (Stockholm University)|
"A-to-I editing of microRNAs in the mammalian brain increase during development"
|8:25 pm - 8:30 pm ||Discussion|
|8:30 pm - 8:45 pm ||Bhalchandra S. Rao (Ohio State University)|
"Novel repair activities and regulation of Thg1 enzymes: New frontiers for 3'-5' nucleotide additions"
|8:45 pm - 8:50 pm ||Discussion|
|8:50 pm - 9:05 pm ||Maria Werner (International Institute of Molecular and Cell Biology, Warsaw)|
"Identification and characterization of human mRNA cap2 methyltransferase"
|9:05 pm - 9:10 pm ||Discussion|
|9:10 pm - 9:25 pm ||Isao Masuda (University of Tokyo)|
"Mitochondrial gene expression of a parasitic protist Perkinsus requires extensive frameshift at all AGG and CCC codons"
|9:25 pm - 9:30 pm ||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Structure, function and specificity of editing/modification systems|
|Discussion Leader: Brian Smith (Ohio State University) and Jeremy Wilusz (Massachusetts Institute of Technology)|
|9:00 am - 9:15 am ||Rena A. Goodman (University of California, Davis)|
"Investigation of a new A-to-I editing site: Structural probing and functional consequences"
|9:15 am - 9:20 am ||Discussion|
|9:20 am - 9:35 am ||Kimberly Prohaska (University of Rochester)|
"Novel research tools for dissociating RNA from APOBEC3G"
|9:35 am - 9:40 am ||Discussion|
|9:40 am - 9:55 am ||Jessica L. Spears (Ohio State University)|
"Trypanosoma brucei ADAT2/3 tRNA deaminase: Conserved active site residues, unique active site architecture"
|9:55 am - 10:00 am ||Discussion|
|10:00 am - 10:15 am ||Michael L. Hayes (University of California, Irvine)|
"The evolution of editing PPRs reveals highly conserved structural motifs that suggest a mechanism for RNA binding and substrate specificity"
|10:15 am - 10:20 am ||Discussion|
|10:20 am - 10:35 am ||Leila Rieder (Brown University)|
"A tale of two (or three, or four) structures: In vivo demonstration of long-range secondary and tertiary RNA structures directing ADAR modification"
|10:35 am - 10:40 am ||Discussion|
|10:40 am - 10:55 am ||Takanori Yano (University of Tokyo)|
"Functional analysis of A-to-I editing in the intronic region of human mRNAs"
|10:55 am - 11:00 am ||Discussion|
|11:00 am - 12:30 pm||Poster Session II|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 3:00 pm||Bioinfomatic and evolutionary analysis of editing and modification|
|Discussion Leader: Dylan Dupuis (Lehigh University) and Michael Guy (University of Rochester)|
|1:30 pm - 1:45 pm ||Shahar Alon (Tel Aviv University)|
"Systematic identification of A-to-I editing in mature miRNAs"
|1:45 pm - 1:50 pm ||Discussion|
|1:50 pm - 2:05 pm ||Aaron Yap (University of Western Australia)|
"Surveying the A. thaliana editotype"
|2:05 pm - 2:10 pm ||Discussion|
|2:10 pm - 2:25 pm ||Claire Hamilton (Rockefeller University)|
"Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA editing targets in transcript 3'UTRs"
|2:25 pm - 2:30 pm ||Discussion|
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill out GRS Evaluation Forms|
|3:00 pm||Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.|