| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session |
| Discussion Leader: Dewi Harjanto (Rockefeller University) |
| 3:45 pm - 4:15 pm | Keynote Speaker: Kazuko Nishikura (The Wistar Institute)
"RNA editor acts as RNA silencer"
|
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Biological Roles of Editing and Modification |
| Discussion Leader: Isabel Vallecillo-Viejo (University Of Puerto Rico) and Rui Zhang (Stanford University) |
| 7:30 pm - 7:50 pm | Ylva Ekdahl (Stockholm University)
"Editing of miRNAs may affect dendritic outgrowth during development by fine-tuning Pumilio 2 protein levels"
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| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Meng How Tan (Stanford University)
"A Quantitative Atlas of RNA Editing Sites in Mammals"
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| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Mikaela Behm (Stockholm University)
"Regulation of A-to-I RNA editing during brain development and neuronal activation"
|
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Xiao Wang (The University Of Chicago)
"N6-methyladenosine-specific RNA-binding proteins in mRNA regulation"
|
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Structure, function and specificity of editing/modification systems |
| Discussion Leader: Dan Dominissini (Tel-Aviv University) and Bhalchandra Rao (Ohio State University) |
| 9:00 am - 9:20 am | Eric Fritz (Rockefeller University)
"Genome-wide analyses demonstrate that AID is neither demethylates DNA nor edits RNA in activated B cells"
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| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | William Swinehart (Ohio State University)
"Inefficient substrate recognition of a multi-functional tRNA modification enzyme"
|
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Michael Guy (University Of Rochester)
"Conserved circuitry in eukaryotes for crucial Trm7 modifications of the tRNA anticodon loop"
|
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Yicheng Long (Ohio State University)
"Multiple functions of a family of 3'-to-5' polymerases in Dictyostelium discoideum"
|
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Bioinformatic and Evolutionary Analysis of Editing and Modification |
| Discussion Leader: Cai Chen (The Ohio State University) and Takuma Suematsu (University Of California, Irvine) |
| 1:30 pm - 1:50 pm | Gokul Ramaswami (Stanford University)
"Identifying RNA Editing Sites Using RNA Sequencing Data Alone" |
| 1:50 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:20 pm | Cintia Hongay (Clarkson University)
"The role of IME4 in metazoan development" |
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
