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| Welcome remarks and overview: Jack E. Dixon and Ron Taussig,
University of Michigan |
| |
Sunday, June 10, 2001 Evening session 7:30-9:30 PM | G protein-coupled receptors |
|
| Chair - Michel Bouvier |
| 7:30 PM | Michel Bouvier - University of Montreal
"Receptor Dimerization" |
| 8:00 PM | Linda Hicke - Northwestern
"Receptor Ubiquitination" |
| 8:30 PM | Krzysztof Palczewski - University of Washington
"Rhodopsin Structure" |
| 9:00 PM | Stephen M. Lanier - Medical University of South Carolina, Charleston "Novel Regulators of G Proteins" |
Monday, June 11, 2001 Morning Session 9:00-12:30 | Kinases |
|
| Chair - Susan Taylor |
| 9:00 AM | Tony Pawson - Toronto
"New Paradigms in Signaling Complexes" |
| 9:40 AM | Susan Taylor - UCSD
"Kinase Structure, Nuclear Import and Export: The Controls of Signaling Mechanisms" |
| 10:20 AM | Tony Hunter - Scripts
"Tyrosine Kinases" |
| 11:10 AM | John Scott - Vollum
"Protein Kinase A Anchoring Proteins" |
| 11:40 AM | John Kuriyan - Rockefeller University
"Kinase Structures" |
| 12:30 PM | Lunch |
| Afternoons | Free of all formal activity |
| 4:30-6:00 PM | Poster Session |
| 6:00 PM | Dinner |
Monday, June 11, 2001 Evening session 7:30-9:30 PM | Rho Signaling |
|
| Chair - Paul Sternweiss |
| 7:30 PM | Kun-Liang Guan - University of Michigan
"A New Family of Receptors Which Are Directly Coupled to Cytosketal Activity Proteins" |
| 8:00 PM | John Sondek - University of North Carolina "Structural basis for rho-GEF specificity" |
| 8:30 PM | Diane Barber - UCSF,
"Plasma membrane anchors as integrators for cytoskeletal organization" |
| 9:00 PM | Paul Sternweis - UT Southwestern, Dallas
"Regulation of Rho-dependent pathways by G13." |
Tuesday, June 12, 2001 Morning Session 9:00-12:30 | Signaling |
|
| Chair - Robert Geahlen |
| 9:00 AM | Joan Brugge - Harvard University
"Intergrin Signaling Compleses" |
| 9:40 AM | Jim Darnell - Rockefeller
"STATs Are Where Its ATS" |
| 10:20 AM | Robert Geahlen - Purdue University
"Kinases of the Immune System: Novel Signaling Strategies" |
| 11:00 AM | Marsha Rosner, University of Chicago "PKC Activates Raf-1 Signaling through a Mechanism Involving RKIP" |
| 11:30 AM | David Virshup - University of Utah "Phosphorylation regulates the ticking of the circadian clock." |
| 12:30 PM | Lunch |
| Afternoons | Free of all formal activity |
| 4:30-6:00 PM | Poster Session |
| 6:00 PM | Dinner |
Tuesday, June 12, 2001 Evening Session 7:30-9:30 PM | Cyclic Nucleotides |
|
| Chair - Marco Conti |
| 7:30 PM | Lonny Levin - Cornell University
"Bicarbonate Sensing by Soluble Adenylyl cyclase" |
| 8:00 PM | Peter Devreotes - Johns Hopkins
"Chemoattractant Gradient Sensing Mechanisms in Eucaryotic" |
| 8:30 PM | Marco Conti - Stanford
"Phosphodiesterases" |
| 9:00 PM | Jaime Athos - University of Washington
"Adenylyl Cyclase Knockouts" |
| 9:30 PM | Roger Sunahara - University of Michigan (UT Southwestern Med. School)
"G Protein/Adenylyl Cyclase Structure" |
Wednesday, June 13, 2001 Morning Session 9:00-12:30 | Kinase Signaling Cascades |
|
| Chair - Melanie Cobb |
| 9:00 AM | Melanie Cobb - UT Southwestern, Dallas
"MAP Kinase Signaling Complexes" |
| 9:40 AM | Elaine Elion - Harvard University
"MAP Kinase Signaling Strategies" |
| 10:20 AM | Tyler Jacks - MIT
"Animal Models for Cancer" |
| 11:00 AM | Natalie Ahn - University of Colorado
"Regulation by MAP kinase pathways"
|
| 11:40 AM | Kim Orth - University of Michigan
"Interception of Signaling Cascades and Bacterial Pathogenesis" |
| 12:30 PM | Lunch |
| Afternoons | Free of all formal activity |
| 4:30-6:00 PM | Poster Session |
| 6:00 PM | Dinner |
Wednesday, June 13, 2001 Evening session 7:30-9:30 PM | G-Proteins |
|
| Chair - Heidi Hamm |
| 7:30 PM | Heidi Hamm - Vanderbilt University
"Receptor-G protein interaction" |
| 8:00 PM | Lew Luttrell - Duke University
"G Protein Regulation of MAP Kinase Signaling" |
| 8:30 PM | Ted Meigs, Duke University "A link between G12 proteins and the cadherin/catenin pathway"
|
| 9:00 PM | Michael Koelle, - Yale University
"Genetics and FRGS function" |
Thursday, June 14, 2001 Morning Session 9:00-12:30 | Phosphatases and Other Signaling Paradigms |
|
| Chair - Morris White |
| 9:00 AM | Tak Mak - Toronto
"PTEN Deficient Mice and Cancer Progression" |
| 9:40 AM | Ben Neel - Harvard
"SH2-Protein Tyrosine Phosphatases" |
| 10:20 AM | Marc Mumby - UT Southwestern
"Targeting and Functions of Protein Phosphatase 2A" |
| 11:00 AM | Alan Saltiel - Pfizer Industries
"Glucose Transporters" |
| 11:40 AM | Morris White - Harvard
"IRS Knock-out Mice: What Can They Tell Us About Human Diabetes?" |
| 12:30 PM | Lunch |
| Afternoons | Free of all formal activity |
| 4:30-6:00 PM | Poster Session |
| 6:00 PM | Dinner |
| |
Thursday, June 14, 2001 Evening session 7:30-9:30 PM | KEYNOTE SPEAKER |
|
|
| 7:30 PM | Mark Hochstrasser - Yale University
"Ubiquitin-like Proteins" |
|
| Breakfast |
| Conferees depart |