Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Staphylococcal Cell Biology: Towards Novel Therapeutics
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:10 pm
"Staphylococcus aureus Cell Wall Architecture and Dynamics"
8:10 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Misconceptions About Staphylococcus aureus Cell Division"
8:45 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Structure and Mechanism of Genome Delivery of Tailed Phages Infecting Staphylococcus aureus "
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Staphylococcal Interactions Within the Microbial Community
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:40 am
"Picking Sides: Bacterial Interactions in the Nose"
9:40 am - 9:55 am
Discussion
9:55 am - 10:25 am
"Probiotics to Prevent Staphylococcus aureus Disease?"
10:25 am - 10:40 am
Discussion
10:40 am - 11:10 am
Coffee Break
11:10 am - 11:40 am
"Effect of Bacterial Competition for a Host Receptor on Nasal Colonization"
11:40 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Longitudinal Staphylococcus aureus Nasal Colonization and Microbiome Disruption in Adolescents"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Lipoprotein-Derived Linear Signal Peptides: Unravelling Their Biological Potential in Staphylococcus aureus Pathogenesis"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Strategies for Nutrient Acquisition During Colonization and Infection
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"The Intersection of Nutrition and Infection at the Host-Microbe Interface"
6:35 pm - 6:50 pm
Discussion
6:50 pm - 7:10 pm
"Built-in Redundancy in Nutrient Acquisition in the Staphylococci"
7:10 pm - 7:25 pm
Discussion
7:25 pm - 7:45 pm
"Metal Ion Homeostasis in Staphylococcus aureus "
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Host-Pathogen Interactions and the Balance of Power
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Staphylococcal Toxins and Bacterial Immune Evasion"
9:35 am - 9:50 am
Discussion
9:50 am - 10:10 am
"The Staphylococcus aureus Type VII Secretion System"
10:10 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"The Impact of Staphylococcus aureus WTA Glycosylation on Immune Detection"
11:15 am - 11:30 am
Discussion
11:30 am - 11:50 am
"The Host Fights Back: An Innate Strategy to Block Pore-Forming Toxins"
11:50 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
"The Staphylococcus aureus lrgAB Operon Is Important for Anaerobic Growth on Pyruvate"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Systems Biology of Staphylococcal Pathogenesis
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:30 pm
"Unraveling Post-Transcriptional Regulatory Networks Controlling Rapid Adaptive Responses"
6:30 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Expanding the Operon Concept: Non-Contiguous Operon"
7:05 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Big Data: What Is Learned with Scale?"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Immune Response to Staphylococcal Infections: Towards Effective Control Strategies
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Immunometabolomic Crosstalk Between Staphylococcus aureus Biofilm and Leukocytes Influences Infection Persistence"
9:35 am - 9:50 am
Discussion
9:50 am - 10:15 am
"Staphylococcus aureus and Persistent Type 2 Inflammation in Airway Disease"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"IL-17 and Beyond: T Cells in Immunity to Staphylococcus aureus Skin Infections"
11:25 am - 11:40 am
Discussion
11:40 am - 11:55 am
"A Single DNA Repair Pathway Enables Staphylococcal Survival During Exposure to Host Immune Cells and Antibiotics"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
"Calprotectin Modulates Neutrophil Function Increasing the Susceptibility of Lupus Patients to Staphylococcus aureus Infections"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Continuing Evolution of Staphylococcal Virulence and Resistance
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"Evolutionary Genomics of Staphylococcus aureus Infections"
6:35 pm - 6:50 pm
Discussion
6:50 pm - 7:10 pm
"Functions of the Conserved ORFs Carried by SCCmec"
7:10 pm - 7:25 pm
Discussion
7:25 pm - 7:45 pm
"The Ecological and Evolutionary Underpinnings of Virulence in Staphylococcus saprophyticus "
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Clinical Disease: Towards Precision Medicine
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"The Innate Immune Response Induces Antibiotic Tolerance in Staphylococcus aureus "
9:35 am - 9:50 am
Discussion
9:50 am - 10:15 am
"Clinical Perspective on Recurring Staphylococcal Infections"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"You're Part of the Problem: Host Genetic Susceptibility to Staphylococcus aureus Infection"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"Dissecting the Molecular Basis for Invasive and Persistent Staphylococcus aureus Infections"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Conversion of Staphylococcal Pathogenicity Islands to CRISPR-Carrying Antibacterial Agents that Cure Infections in Mice"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:10 pm
"Host-Specialized Fibrinogen-Binding by a Bacterial Surface Protein Promotes Biofilm Formation and Innate Immune Evasion"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
"Exact Match Compression for Identification of Genomic Novelty in the Staphylococci"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"A Role for Monocyte Conversion During Staphylococcus aureus Skin Infection"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Staphylococcal Alpha-Toxin Induces Fractalkine Release via ADAM10 Activity and Alters Monocyte Functional Response in the Lung Mucosa During Infection"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"Peptidyl-Prolyl Cis/Trans Isomerases (PPIases) Contribute to Staphylococcus aureus Virulence via the Regulation of Hemolytic Toxins"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Staphylococcus aureus Mediated Biotransformation of Natural Products During Polymicrobial Interactions"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"An ECF-Type Transporter Governs Heme Acquisition by Staphylococcus lugdunensis "
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"The Cystine Transporters, TcyABC and TcyP, Facilitate Nutrient Sulfur Acquisition by Staphylococcus aureus During Infection"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure