| SUNDAY |
| 4:00 pm - 8:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | Foundations and Current Approaches |
| Discussion Leader: Peter von Hippel (Univ. of Oregon) |
| 7:40 pm - 8:15 pm | Ken Dill (Stonybrook)
"Physics of proteomes"
|
| 8:15 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:05 pm | Elliot Elson (Washington University School of Medicine)
"Fluctuation measurements"
|
| 9:05 pm - 9:20 pm | Discussion |
| 9:20 pm - 9:25 pm | Michael Halter (NIST)
"Predicting rates of cell state change due to stochastic fluctuations using a data-driven landscape model"
|
| 9:25 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Stochasticity: Biology meets Physics |
| Discussion Leader: Nancy Thompson (UNC) |
| 9:30 am - 10:05 am | Mans Ehrenberg (Univ. Uppsala)
"Accuracy, fidelity, and central dogma"
|
| 10:05 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 10:50 am - 11:25 am | Tom Chou (UCLA)
"Stochastic nucleation and self assembly in cell biology"
|
| 11:25 am - 11:40 am | Discussion |
| 11:40 am - 12:15 pm | Peter von Hippel (Univ. Oregon)
"Fluctuations in replication"
|
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Emergent Phenomena in Cellular Biology |
| 7:30 pm - 7:50 pm | Discussion Leader: Chao Tang (Peking Univ./UCSF)
"Cellular decision making under noisy conditions"
|
| 7:50 pm - 8:25 pm | James Ferrell (Stanford Univ.)
"Feedback and cell fate switching"
|
| 8:25 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:15 pm | X. Sunney Xie (Harvard)
"Single Cell Dynamics Probed by Imaging and Sequencing"
|
| 9:15 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Fluctuations and Stochasticity at All Scales |
| Discussion Leader: X. Sunney Xie (Harvard) |
| 9:10 am - 9:45 am | Johan Elf (Univ. Uppsala)
"Fluctuations in cellular regulations"
|
| 9:45 am - 10:00 am | Discussion |
| 10:00 am - 10:05 am | Elizabeth Read (UC Irvine)
"Stochastic effects in intra-host HIV evolution"
|
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:15 am | Anand Banerjee (NIH)
"Stochastic nature of clathrin-coated pit assembly"
|
| 10:15 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 10:50 am - 11:25 am | Daniel Needlman (Harvard Univ.)
"Self-organizing subcellular structures"
|
| 11:25 am - 11:40 am | Discussion |
| 11:40 am - 12:15 pm | Susan Rosenberg (Baylor College of Medicine)
"Stress-induced mutation and evolvability"
|
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Thermodynamics and Stochastic Open Systems |
| Discussion Leader: Ken Dill (Stonybrook) |
| 7:40 pm - 8:15 pm | Udo Seifert (Univ. Stuttgart)
"Stochastic thermodynamics"
|
| 8:15 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:05 pm | Massimiliano Esposito (University of Luxembourg)
"Open systems dynamics"
|
| 9:05 pm - 9:20 pm | Discussion |
| 9:20 pm - 9:25 pm | Srabanti Chaudhury (Los Alamos National Laboratory)
"Universality of Poisson indicator and Fano factor of transport event statistics in ion channels and enzyme kinetics"
|
| 9:25 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Integrating stochastic dynamic models with measurements |
| 9:00 am - 9:30 am | Discussion Leader: Ivet Bahar (U. Pittsburgh)
"Coarse-graining supramolecular structure and dynamics for subcellular simulations" |
| 9:30 am - 10:05 am | Denis Tsygankov (UNC)
"Cellular signaling dynamics and models"
|
| 10:05 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 10:50 am - 11:25 am | Jian-shu Cao (MIT)
"Statistics and single molecules"
|
| 11:25 am - 11:40 am | Discussion |
| 11:40 am - 12:15 pm | Sui Huang (Institute for Systems Biology)
"Population dynamics with phenotype conversion in mammalian cell"
|
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 7:30 pm - 9:30 pm | Force, Mechanics, and Polarity of Cells |
| 7:30 pm - 7:50 pm | Discussion Leader: William Loomis (UCSD)
"Chemotactic motility" |
| 7:50 pm - 8:25 pm | Lani Wu (UTSW)
"Cellular polarity circuit"
|
| 8:25 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:15 pm | Michael Murrell (Univ. Chicago)
"Biomechanics of cells"
|
| 9:15 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Biological Dynamics in Space and Time |
| Discussion Leader: Samuel Isaacson (Boston Univ.) |
| 9:10 am - 9:45 am | Mark Goulian (Univ. Penn)
"Cell variability in phosphorelay signaling"
|
| 9:45 am - 10:00 am | Discussion |
| 10:00 am - 10:05 am | Srividya Iyer Biswas (Univ. Chicago)
"Scaling of fluctuations in exponential growth and division in single cells"
|
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:15 am | Nika Shakiba (Univ. Toronto)
"A Compartmental Probabilistic Model of Heterogeneity in Reprogramming to Pluripotency"
|
| 10:15 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 10:35 am - 11:10 am | Matt Scott (Waterloo)
"Stochastic reaction diffusion"
|
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:05 pm | Doug Barrick (Johns Hopkins Univ.)
"Protein dynamics and landscape"
|
| 12:05 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Stochastic Nonlinear Dynamics, Models and Computations |
| Discussion Leader: Elliot Elson (Washington Univ.) |
| 7:40 pm - 8:15 pm | Albert Goldbeter (Univ. Brussels)
"Biological clocks"
|
| 8:15 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:05 pm | Rachel Kuske (UBC)
"Stochastic models of biological systems"
|
| 9:05 pm - 9:20 pm | Discussion |
| 9:20 pm - 9:25 pm | Sandeep Choubey (Brandeis Univ.)
"Dynamics of transcription initiation from electron microscopy images of transcribing polymerases"
|
| 9:25 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |