Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Statistical Mechanics in Molecular Biology
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:25 pm
8:25 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
"Gene Regulation at the Single Molecule Level"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Stochastic Dynamics of Biological Molecules and Networks
9:00 am - 9:30 am
"A Structural Mechano-Chemical Model for Dynamic Instability of Microtubules"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Nonequilibrium Dynamics and Thermodynamics in Cell Fate Decision Making"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"Using a System's Equilibrium Behavior to Reduce Its Energy Dissipation in Non-Equilibrium Processes"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Theory of Diffusion-Influenced Reaction Networks"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Mapping Epigenetic Landscapes Using Dynamic Perturbations"
11:40 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Synthetic NF-kB: A Building Approach to Study Complex Signaling Behaviors"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Single-Cell Biophysics: Measurement and Analysis
7:30 pm - 8:00 pm
"Stochasticity and Control in Mitochondrial Division"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"How Microbes Decide When to Divide: From Bacteria to Cyanobacteria"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Imaging Dynamic Subcellular Organization that Mediates Cell Fate"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
"Equilibrium and Nonequilibrium Dynamics in the Behavior of Bacterial Flagellar Motor"
9:15 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Statistical Physics of Evolution and Disease
9:00 am - 9:30 am
"Does Evolution Care About Bits? Information as Currency in Nature's Stock Market"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Dynamics of Viral Mutation and Evolution"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Artificial Selection of Microbial Communities"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Codon-Programmable Noise in Gene Expression Dictates Cell-to-Cell Variability in Nutrient Poor Environments"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Self-Organization and Phase Transitions in Biological Systems
7:30 pm - 8:00 pm
"Collective Behavior Underlying Mechanobiology of Cells and Tissues: Role of Criticality and Compositeness"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Modeling Nonequilibrium Self-Assembly in the Cell Through Reaction-Diffusion Simulation"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Quantifying Nonequilibrium Fluctuations in Living Matter"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
"Arcs, Flows and Waves: Cytoskeletal Dynamics and Mechanosensing in Immune Cells"
9:15 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell State Space Dynamics: Landscapes and Trajectories for Differentiation and Behavior
9:00 am - 9:30 am
"Emergent Simplicity in Stochastic Individual-Cell Dynamics"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Reconstructing Cell Dynamics from Single Cell Trajectories"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Kalman-Like Self-Tuned Sensitivity in Biological Clocks"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Generic Properties of Stochastic Entropy Production"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Stochastic Physics of the Central Dogma
7:30 pm - 8:00 pm
"Long Range Communication in the Nucleus"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Mechanism of Chromatin Domain Formation Revealed by Epigenetic Energy Landscape"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Stochastic Modeling of Single RNA Translation Dynamics"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
"Buffering of Gene Expression Noise by Liquid Compartments"
9:15 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
From Cells to Organisms: Stochastic Dynamics Across Biological Scales
9:00 am - 9:30 am
"Persistent Gene Expression States Drive Lifespan Differences Among Otherwise-Identical C. elegans "
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Stochastic Cell Fate Specification in Fly Eyes and Human Retinal Organoids"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Run, Wander and Drift: Interplay of Physical Mechanisms for Intracellular Transport"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Dynamics of the Segmentation Clock"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Fluctuations in Cellular and Subcellular Structure
7:30 pm - 8:00 pm
"Active Enzymes as Biological Active Matter"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Experimental Measurements of Dissipation and Efficiency in an Active Cytoskeletal Material"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"The Biological Catch Bond Suppresses Fluctuations in Nonequilibrium Systems"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
"Forces and Torques in the Mitotic Spindle"
9:15 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure