Find a Conference

Phishing Alert - GRC SPEAKERS AND DISCUSSION LEADERS ARE BEING TARGETED BY PHISHING ATTEMPTS DESIGNED TO COLLECT PAYMENT FOR REGISTRATION OR LODGING. CLICK HERE FOR MORE DETAILS

Systems Aging

Gordon Research Conference

Complexities of Aging Across Species, Evolution, Reproduction, Human Longevity and Frailty

June 14 - 19, 2026

Apply Now

GRC Education Requirements: Undergraduates or those who have not obtained a bachelor's degree in science/engineering (or acceptable equivalent) are not eligible to apply to attend Gordon Research Conferences or Seminars.

Chair

Vice Chairs

and

Grand Summit Hotel at Sunday River

97 Summit Road

Newry, Maine, United States

Venue and Travel Information

Application Information

Applications for this meeting must be submitted by May 17, 2026. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the conference chair if more seats become available due to cancellations.

Conference Description

The Systems Aging GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes an array of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

The Systems Aging conference in 2026 will explore aging through evolution, reproduction, human longevity and frailty. It will cover invertebrate and vertebrate models, while digging in to molecular mechanisms, biomarkers, and systems immunology, offering insights into aging biology and potential interventions.

Please apply early, as we expect the conference to be oversubscribed before the May deadline.

February 1: Oral abstract submission deadline

May 17: Poster abstract submission deadline

Related Meeting

This GRC will be held in conjunction with the "Systems Aging" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Evolutionary Perspectives on Aging Discussion Leader:
7:40 pm - 7:50 pm	Introduction by Discussion Leader
7:50 pm - 8:05 pm	"Building Haystacks and Finding Needles in the Genomics of Ageing"
8:05 pm - 8:15 pm	Discussion
8:15 pm - 8:30 pm	"Why Live Longer on Less and Why the Sexes Age Differently"
8:30 pm - 8:40 pm	Discussion
8:40 pm - 8:50 pm	"Evolvable Soma Theory: Redefining the Role of Evolution in Ageing"
8:50 pm - 8:55 pm	Discussion
8:55 pm - 9:05 pm	"Infectious Diseases-Driven Evolution of Life Histories in Eusocial Species"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:20 pm	Short Talk Selected from Poster Abstracts
9:20 pm - 9:25 pm	Discussion
9:25 pm - 9:30 pm	General Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Invertebrate Models of Aging Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:25 am	"Improving DNA Double-Strand Break Repair to Extend the Mitotic Lifespan"
9:25 am - 9:35 am	Discussion
9:35 am - 9:50 am	"Disequilibrium in Organismal mRNA Content During Aging"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Epigenomic Dynamics in Ageing: From Chromatin Architecture to Lifespan Regulation"
10:15 am - 10:25 am	Discussion
10:25 am - 10:50 am	Coffee Break
10:50 am - 11:00 am	"Powerful Genetic Dissection of Lifespan Variation in Drosophila melanogaster"
11:00 am - 11:05 am	Discussion
11:05 am - 11:15 am	"Genetics, Genomics, and Metabolomics of Exceptional Longevity and its Variation in the World's Longest-Lived Animal"
11:15 am - 11:20 am	Discussion
11:20 am - 11:30 am	"Cell-Cycle Dynamics Encode Latent Damage States Underlying Replicative Aging"
11:30 am - 11:35 am	Discussion
11:35 am - 11:45 am	"Aging without Degeneration: Adaptive Transcriptional Reallocation Supports Nervous System Maintenance in a Non-senescent Invertebrate Model"
11:45 am - 11:50 am	Discussion
11:50 am - 12:00 pm	Late-Breaking Topic
12:00 pm - 12:05 pm	Discussion
12:05 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Vertebrate Models of Aging Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 7:55 pm	"Population Size Shapes the Evolution of Lifespan"
7:55 pm - 8:05 pm	Discussion
8:05 pm - 8:20 pm	"A Comparative Approach to Uncover the Mechanisms of Bats’ Extended Healthspans"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Age-Resilient Epigenetic Landscapes in the Axolotl"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:05 pm	"Sterilization and Contraception Increase Lifespan across Vertebrates"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:20 pm	Short Talk Selected from Poster Abstracts
9:20 pm - 9:25 pm	Discussion
9:25 pm - 9:30 pm	General Discussion
Tuesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Genome, Epigenome and Chromatin Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:25 am	"The Network Effect: How Protein Networks Control DNA Repair and Shape Cellular Aging"
9:25 am - 9:35 am	Discussion
9:35 am - 9:50 am	"DNA Damage and Systemic Aging: The Connection with Nutrition, Gene size, Transcription stress and Neurodegeneration"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Somatic Mutation, Genome Mosaicism, and Aging"
10:15 am - 10:25 am	Discussion
10:25 am - 10:50 am	Coffee Break
10:50 am - 11:00 am	"Loss of Tissue-Specific DNA Methylation Identify with Age"
11:00 am - 11:05 am	Discussion
11:05 am - 11:15 am	"Cell-Type Specific Disease Scoring in Alzheimer's Disease"
11:15 am - 11:20 am	Discussion
11:20 am - 11:30 am	"The Polaris Platform for Omics and Longevity AI-Assisted Research Integration and Scoring"
11:30 am - 11:35 am	Discussion
11:35 am - 11:45 am	"Conserved Master Regulators Orchestrate Cellular Reprogramming-Induced Rejuvenation"
11:45 am - 11:50 am	Discussion
11:50 am - 12:00 pm	Late-Breaking Topic
12:00 pm - 12:05 pm	Discussion
12:05 pm - 12:15 pm	Late-Breaking Topic
12:15 pm - 12:20 pm	Discussion
12:20 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Reproductive Aging Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 7:55 pm	"Evading Ageing: Lessons from Oocytes"
7:55 pm - 8:05 pm	Discussion
8:05 pm - 8:20 pm	"Biological Underpinnings of the Pattern of Human Ovarian Follicle Loss Across the Lifespan"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Ovarian Aging and its Health Impacts"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:05 pm	"Protein Homeostasis in Mammalian Oocytes during Fertility and Reproductive Aging"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:20 pm	"Characterization of the Epigenetic Deterioration of Oocytes and Surrounding Granulosa Cells with Age and Their Epigenetic Artificial Rejuvenation"
9:20 pm - 9:25 pm	Discussion
9:25 pm - 9:30 pm	General Discussion
Wednesday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	Systems Aging and Immunology Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:25 am	"Biobank-Scale Genetic Epidemiology, Immunology and Aging"
9:25 am - 9:35 am	Discussion
9:35 am - 9:50 am	"Human Immune Aging is a Developmental Process with Clinical Implications"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Diverging Paths of Brain Aging: From Cellular Microenvironments to Systemic Coordination"
10:15 am - 10:25 am	Discussion
10:25 am - 10:50 am	Coffee Break
10:50 am - 11:05 am	"Immune Health and Aging in Humans"
11:05 am - 11:15 am	Discussion
11:15 am - 11:25 am	"A Systems Biology Approach to Hormesis"
11:25 am - 11:30 am	Discussion
11:30 am - 11:40 am	"Defining the Role of Adipose-Glucocorticoid Signaling in Age-Related Metabolic Disorders and Cellular Senescence."
11:40 am - 11:45 am	Discussion
11:45 am - 11:55 am	"Maternal Obesity and Perinatal Obesogenic Exposure Trigger Genomic Stress Responses Driving Premature Alveolar Epithelial Aging and Emphysema in life."
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Frailty Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 7:55 pm	"Frailty, Entropy, Energy, and Aging"
7:55 pm - 8:05 pm	Discussion
8:05 pm - 8:20 pm	"Decoding the Biology of Frailty through Genomic Methods"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Insights into Frailty Mechanisms Using Longitudinal Mouse Studies in Both Sexes"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:10 pm	"Is Aging Simpler Than We Think? Toward Principles of Damage Accumulation"
9:10 pm - 9:20 pm	Discussion
9:20 pm - 9:30 pm	General Discussion
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Biomarkers and Quantitative Aging Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:25 am	"Strategies for Building Causal Epigenetic Clocks"
9:25 am - 9:35 am	Discussion
9:35 am - 9:50 am	"Biomarkers of Aging Consortium: Updates and Future Perspectives"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"The Aging of Molecules: From DNA to Proteins"
10:15 am - 10:25 am	Discussion
10:25 am - 10:50 am	Coffee Break
10:50 am - 11:05 am	"Measuring Aging at Scale"
11:05 am - 11:15 am	Discussion
11:15 am - 11:25 am	"Responsive and Reliable Biomarkers of Aging: Rebuilding Epigenetic Clocks for Clinical Translation"
11:25 am - 11:30 am	Discussion
11:30 am - 11:40 am	"Geroprotectors Hiding in Plain Sight: Systematic Identification of Approved Drugs that Reduce Organ-Specific Biological Age"
11:40 am - 11:45 am	Discussion
11:45 am - 11:55 am	"Metabolomic Predictions for Anti-Aging Drugs"
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	"Face Photo-Based Measurements of Biological Age"
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:25 pm	Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Human Longevity Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 7:55 pm	"It's a Family Affair: Identification and Characterization of Rare Protein-Altering Genetic Variants Linked to Familial Longevity"
7:55 pm - 8:05 pm	Discussion
8:05 pm - 8:20 pm	"Cellular Senescence and Human Longevity: Implications in Senotherapy"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Mechanisms of Longevity"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:05 pm	"Metformin and Clemastine Rejuvenate Measures of DNA Methylation Age and Promote CNS Remyelination in Adults with Multiple Sclerosis"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:20 pm	Short Talk Selected from Poster Abstracts
9:20 pm - 9:25 pm	Discussion
9:25 pm - 9:30 pm	Closing Remarks
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Conference Links

Conference History Systems Aging (GRS) Contribute Financially to This Conference

Conference Fees

Similar Conferences

Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Preparing your GRC poster

Funding Opportunities

Financial assistance is available beginning in 2026 for qualified applicants through the Carl Storm Opportunity Fellowships program. Learn more.

Registration Fees

Conferee Single Room:

$1,755.00

Conferee Shared Room:

$1,375.00

Conferee Off-Site:

$985.00

Guest Single Room:

$1,535.00

Guest Shared Room:

$1,155.00

Guest Off-Site:

$765.00

Child 4-12 yrs Shared Room:

$578.00

Child 4-12 yrs Off-Site:

$383.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Bus Arriving:

$65.00

Bus Departing:

$65.00

Additional Fee Info

Similar Gordon Research Conferences and Seminars

Biology of Aging

July 25 - 30, 2027

Cell Death

May 17 - 22, 2026

Chronobiology

June 20 - 25, 2027

Physiology, Biology and Pathology of Phosphate

February 14 - 19, 2027

Stress Proteins in Growth, Development and Disease

July 4 - 9, 2027

Systems Aging (GRS)

June 13 - 14, 2026

Thiol-Based Redox Regulation and Signaling

July 12 - 17, 2026

Contact Us

MyGRC Account
Check your application status, complete your registration, update your poster, change your rooming preference, make a bus reservation, print an invitation letter, print a receipt (which includes verification that you are presenting a poster) or print an invoice by logging into your account.

GRC Venues
Everything you need to know, to plan your trip.

FAQs
Instant answers to common questions.

Tell us how we can help

Call us and leave a detailed message at: 401-783-4011

*This voicemail is only checked once daily. Due to high volume of requests during the conference season, responses may be delayed.

You have no notifications