Sunday |
2:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Signaling Unity Within Epithelial Stem Cell Diversity |
| Discussion Leader: Rongwen Xi (National Institute of Biological Sciences, China) |
7:40 pm - 7:50 pm | Opening Remarks |
7:50 pm - 7:55 pm | Introduction by Discussion Leader |
7:55 pm - 8:35 pm | Roeland Nusse (Stanford University, USA) "Stem Cells in Liver Homeostasis" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:25 pm | Fiona Watt (King's College London, United Kingdom) "In Vitro Approaches to Analyze the Epidermal Stem Cell Niche" |
9:25 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Epithelial Stem Cells and Their Skin Niches |
| Discussion Leaders: Fiona Watt (King's College London, United Kingdom) and Xiaoyang Wu (University of Chicago, USA) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:25 am | Howard Chang (Stanford University, USA) "RNA World and Regulation of Gene Expression" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Pritinder Kaur (Curtin University, Australia) "MSC-Like Dermal Pericytes Influence Epidermal Renewal by Promoting Symmetric Keratinocyte Cell Divisions" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Group Photo / Coffee Break |
10:30 am - 10:50 am | Valerie Horsley (Yale University, USA) "Adipocytes as Niche Cells in Epithelial Tissues" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Xing Dai (University of California, Irvine, USA) "Keeping Skin and Mammary Epithelial Stem/Progenitor Cells Epithelial" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Vladimir Botchkarev (Boston University, USA / University of Bradford, United Kingdom) "Epigenetic Regulation of Epidermal Development and Differentiation" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Aiko Sada (Tsukuba Advanced Research Alliance, University of Tsukuba, Japan) "Stem Cell Lineages of the Interfollicular Epidermis" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Sangbum Park (Yale University, USA) "Coordination of Tissue Homeostasis and Wound Repair Mechanisms in Live Mice" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Epithelial Stem Cells in Translation |
| Discussion Leaders: Michele De Luca (University of Modena and Reggio Emilia, Italy) and Andrea Flesken-Nikitin (Cornell University, USA) |
7:30 pm - 7:55 pm | Michele De Luca (University of Modena and Reggio Emilia, Italy) "Epidermal Stem-Mediated Combined Cell and Gene Therapy for the Treatment of Epidermolysis Bullosa" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:25 pm | Graziella Pellegrini (University of Modena and Reggio Emilia, Italy) "Regenerative Medicine by Corneal Stem Cells: In Vitro and In Vivo Niches" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Nadia Zakaria (Universitaire Ziekenhuis Antwerpen, Belgium) "Collagen Analogs as Scaffolds for Corneal Regeneration" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Catherine Lu (The Rockefeller University, USA) "Identification of Adult Stem Cells in Eccrine Sweat Glands: Wound Repair and Regeneration" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Clare Weeden (The Walter and Eliza Hall Institute of Medical Research, Australia) "Airway Basal Stem Cells Use Error-Prone DNA Repair in Response to DNA Damaging Agents" |
9:25 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Hair Follicle Stem Cells |
| Discussion Leaders: George Cotsarelis (University of Pennsylvania, USA) and Xinhong Lim (Institute of Medical Biology, A*STAR, Singapore) |
9:00 am - 9:25 am | George Cotsarelis (University of Pennsylvania, USA) "Bulge Stem Cells in Mouse and Human Hair Follicles" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Sung-Jan Lin (National Taiwan University, Taiwan) "Environmental Regulation of Hair Follicle Neogenesis and Regeneration" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Tudorita Doina Tumbar (Cornell University, USA) "Genetic and Epigenetic Control of Stem Cell Dynamics in and out the Niche" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Ting Chen (National Institute of Biological Sciences, China) "How to Build a Functional Niche with Stem Cells" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Michael Rendl (Icahn School of Medicine at Mount Sinai, USA) "Regulation of Hair Follicle Formation, Growth and Regeneration by the Mesenchymal Niche" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Isaac Brownell (National Cancer Institute, NIH, USA) "The Perineural Niche as a Regulator of Cutaneous Stem Cells" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Kenneth Lay (The Rockefeller University, USA) "Foxc1 Governs Hair Follicle Stem Cell Quiescence and Niche Maintenance to Preserve Long-Term Tissue-Regenerating Potential" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
2:00 pm - 4:00 pm | Poster Session |
4:00 pm - 6:00 pm | Lung Stem Cells |
| Discussion Leaders: Brigid Hogan (Duke University, USA) and Nan Tang (National Institute of Biological Sciences, Beijing, China) |
4:00 pm - 4:25 pm | Brigid Hogan (Duke University, USA) "Lung Stem/Progenitor Cells and Their Niche During Homeostasis and Repair" |
4:25 pm - 4:35 pm | Discussion |
4:35 pm - 4:55 pm | Barry Stripp (Cedars Sinai Medical Center, USA) "Progenitor Cell Fate in Airway Repair" |
4:55 pm - 5:05 pm | Discussion |
5:05 pm - 5:25 pm | Joo-Hyeon Lee (University of Cambridge, United Kingdom) "Regulatory Crosstalk in Lineage Specification of Epithelial Cells During Lung Repair and Regeneration" |
5:25 pm - 5:30 pm | Discussion |
5:30 pm - 5:40 pm | Ian Driver (University of California, San Francisco, USA) "Single Cell Profiling of Adult Lung Heterogeneity: Identification of Novel Cell Types Involved in Regeneration and Disease" |
5:40 pm - 5:45 pm | Discussion |
5:45 pm - 5:55 pm | Rui Zhao (Genomics Institute of the Novartis Research Foundation, USA) "Tissue Logic in the Airway Epithelium: Plasticity and Regulation" |
5:55 pm - 6:00 pm | Discussion |
6:00 pm | Dinner |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Intestinal Stem Cells |
| Discussion Leaders: Bruce Edgar (Huntsman Cancer Institute, University of Utah Health Care, USA) and Zhengquan Yu (China Agricultural University, China) |
9:00 am - 9:25 am | Bruce Edgar (Huntsman Cancer Institute, University of Utah Health Care, USA) "Regenerative and Tumorigenic Growth of Drosophila
Intestinal Stem Cells" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Tony Ip (University of Massachusetts Medical School, USA) "The Conserved Misshapen-Yorkie Pathway in Drosophila Intestinal Homeostasis" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:35 am | Coffee Break |
10:35 am - 10:55 am | Heinrich Jasper (Buck Institute for Research on Aging, USA) "Age-Related Stem Cell Dysfunction: Lessons from Drosophila" |
10:55 am - 11:05 am | Discussion |
11:05 am - 11:25 am | Rongwen Xi (National Institute of Biological Sciences, China) "Fate Specification and Maintenance
in the Midgut Stem Cell Lineages" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:55 am | Nozomi Nishimura (Cornell University, USA) "In Vivo Imaging of Stem Cells in the Mouse Intestine and Beyond" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:25 pm | Lucy O'Brien (Stanford University, USA) "Motile Stem Cells Exhibit Tissue-Level Spatial Order During Steady-State Organ Renewal but Not Adaptive Organ Growth" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Epithelial Stem Cells of Oral and
Craniofacial Complex |
| Discussion Leaders: Ophir Klein (University of California, San Francisco, USA) and Tsung-Lin Yang (National Taiwan University, Taiwan) |
7:30 pm - 7:50 pm | Ophir Klein (University of California, San Francisco, USA) "Dynamics of Oral and Dental Epithelial Stem Cells During Homeostasis and Regeneration" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Catherine Ovitt (University of Rochester, USA) "Finding a Role for Stem Cells in Salivary Gland Homeostasis" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Yang Chai (University of Southern California, USA) "Molecular Regulation of the Dental Epithelial Stem Cell Niche" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Maria Alcolea (Wellcome Trust/MRC Cambridge Stem Cell Institute, United Kingdom) "Cell Fate Imbalance in the Oesophageal Epithelium: Mutant Cell Competition" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Sarah Knox (University of California, San Francisco, USA) "Peripheral Nerves Selectively Establish, Maintain and Replenish Salivary Gland Architecture via SOX2" |
9:25 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mammary, Prostate, and Ovarian Stem Cells |
| Discussion Leaders: Michael Shen (Columbia University Medical Center, USA) and Chang Liu (Columbia University, USA) |
9:00 am - 9:30 am | Michael Shen (Columbia University Medical Center, USA) "Progenitor Cells and the Origin of Prostate Cancer" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Li Xin (Baylor College of Medicine, USA) "Prostate Epithelial Lineage Hierarchy" |
10:05 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Arial Zeng (Chinese Academy of Sciences, China) "Procr Stem Cells in Mammary Development and Cancer" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:40 am | Jane Visvader (The Walter and Eliza Hall Institute of Medical Research, Australia) "Mapping Stem and Progenitor Cells During Development and Tumorigenesis" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Qiang Lan (Institute of Biotechnology, University of Helsinki, Finland) "Cellular Behavior of Mammary Progenitor Cells During Embryonic Mammary Gland Development" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Winnie Shum (ShanghaiTech University, China) "Epithelial Cellular Communication for a Congenial Niche in Excurrent Duct" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Stem Cells of Transitional Zones |
| Discussion Leaders: Alexander Nikitin (Cornell University, USA) and Guy Lyons (Centenary Institute, Australia) |
4:00 pm - 4:25 pm | Alexander Nikitin (Cornell University, USA) "Transitional Zones, Stem Cells and Cancer" |
4:25 pm - 4:30 pm | Discussion |
4:30 pm - 4:50 pm | Geraldine Guasch (Institut Paoli Calmettes, Cancer Research Center of Marseille, France) "Transitional Epithelium: Merging Microenvironment and Cellular Transformation" |
4:50 pm - 4:55 pm | Discussion |
4:55 pm - 5:15 pm | Yusuke Yamamoto (National Cancer Center Research Institute, Japan) "Enemies from Within: Stem Cells of Metaplastic Precursors of Highly Lethal Cancers" |
5:15 pm - 5:20 pm | Discussion |
5:20 pm - 5:30 pm | Joana Neves (Buck Institute for Research on Aging, USA) "Immune Modulation by MANF Promotes Tissue Repair and Regenerative Success in the Retina" |
5:30 pm - 5:35 pm | Discussion |
5:35 pm - 5:45 pm | Jeff Mumm (Johns Hopkins School of Medicine, USA) "Innate Immune System Regulation of Retinal Regeneration" |
5:45 pm - 5:50 pm | Discussion |
5:50 pm - 6:00 pm | Closing Remarks |
6:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |