Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Vascular Development and Patterning
3:45 pm - 4:15 pm
"Building and Maintaining Biological Tubules"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Multi-Modal Approaches to Vascular Plasticity
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:45 pm
"Mapping Endothelial Plasticity in Liver Fibrosis Reveals Disease-Associated Endothelial Cell Subpopulations Involved in Progressive Liver Fibrogenesis"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
"cSTAR Analysis Identifies Endothelial Cell Cycle as a Key Regulator of Flow-Dependent Artery Remodeling"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:15 pm
"Pericyte Diversity and Phenotypic Switching After Ischemic Stroke in Mice"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Apolipoprotein M-Laden Sphingosine-1-Phosphate Controls Retinal Microvascular Leak in Diabetes"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
"Endothelial Cell Cycle Inhibition Enables Maturation to Normalize the Tumor Vasculature"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
"Circulating Plasma Components From Patients With VEXAS Promote Monocyte and Platelet Adhesion to Cultured Endothelial Cells Under Physiologic Flow Conditions"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
"Nuclear SUN2 Regulates Endothelial Cell Flow Responses and Barrier Function via Long-Range Cell-Matrix Interactions"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Vascular Homeostasis, Regeneration, and Aging
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:15 am
"Dynamics of Cardiac Endothelial Cell Fate and Plexus Maturation during Myocardial Remodeling"
9:15 am - 9:20 am
Discussion
9:20 am - 9:30 am
"Understanding How Structural Components Shape Tissue and Cellular Dynamics by Imaging Live Mice"
9:30 am - 9:35 am
Discussion
9:35 am - 9:45 am
"Investigating the Role of Endothelial Dysfunction in Driving Diastolic Dysfunction in Mice With Inflammatory Arthritis"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"Sex-Specific Endothelial Gene Expression and the Impact of Fructose Metabolism on Cardiovascular Health"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
"SVEP1 Enables Efficient Binding of Angiopoietin-2 to the TIE1 Receptor, Allowing Receptor Phosphorylation and Downstream Signaling"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Loss of Endothelial PGC1α Causes Metabolic Dysfunction-Associated Fatty Liver Disease"
10:30 am - 10:35 am
Discussion
10:35 am - 10:45 am
"The Role of Vascular Endothelial Stem Cells in the Regeneration of the Bone Marrow Vascular Niche"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Development in Vascular Biology
1:30 pm - 2:30 pm
Panel Discussion
Careers in and outside academia, Grant and Scientific Writing, Work-Life Balance
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes