Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Molecular Mechanisms/Structural Biology
7:40 pm - 8:05 pm
"Wnt Signalosome Assembly is Governed by Conformational Flexibility of Axin and AP2 Clathrin Adaptor"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Molecular Mechanisms of the β-Catenin Destruction Complex"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Molecular Insights into Wnt Ligand-Specific Signaling"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Dissecting Molecular Mechanisms of Wnt/β-Catenin Pathway Activation"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Stem Cell Regulation/Tissue Homeostasis
9:00 am - 9:25 am
"How to Grow a Cytoneme for Contact Mediated Intercellular Communication"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Spatial Mapping of Telocytes along the Crypt-Villus Axis Reveals Functional Zonation in the Intestinal Epithelium"
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:40 am
Short Talk Selected from Poster Abstracts
10:40 am - 10:45 am
Discussion
10:45 am - 11:10 am
"A Revised Model of Tissue Regeneration in the Gut Epithelium"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
Short Talk Selected from Poster Abstracts
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:00 pm
Short Talk Selected from Poster Abstracts
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Wnt Signaling in Development
7:30 pm - 7:55 pm
"WNT Signaling Dynamics Controlled by KDM5C during Development Influence Cognition"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
"From Progenitor to Progeny: How Wnt Signaling Shapes Cell Fate Through Cell Cycle Control"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
"GSK3 and Cellular Dormancy: Linking Embryonic Diapause to Cancer Survival"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Wnt Signaling in Cancer and Disease
9:00 am - 9:25 am
"Age- and Dosage-Dependent Effects of Wnt Signaling in Adrenal Cancer"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Interplay of the Clock and Wnt Signaling"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Targeting WNT in Cancer: It’s Complicated"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"Unlocking Pancreatic Islet Regeneration by Modulating Rspo1-Wnt signaling"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Late-Breaking Topic
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Beta-Catenin-Independent Signaling
7:30 pm - 7:55 pm
"Wnt PCP Signaling in Development and Regeneration"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
"Mechano-Gradients Drive Morphogen-Noise Correction to Ensure Robust Patterning"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Therapeutic Intervention/Manipulation
9:00 am - 9:25 am
"Manipulating Cell Fate with Frizzled Agonists"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Novel Synthetic Wnt Signal Agonists and their Therapeutic Applications"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Targeting the Wnt Signaling Modulator DKK1 for Oncology"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Late-Breaking Topic
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:55 pm
"The Impact of Wnt signaling on the Genome"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Short Talk Selected from Poster Abstracts
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Short Talk Selected from Poster Abstracts
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
"Condensates across Functions: β-Catenin in Transcription and Cellular Adhesion"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
9:00 am - 9:25 am
"Regulation of CK1-mediated Dishevelled Phosphorylation by DDX3X RNA Helicase"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Regulation of WNT9A/FZD9 Signaling Specificity"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Late-Breaking Topic
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Late-Breaking Topic
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Short Talk Selected from Poster Abstracts
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Short Talk Selected from Poster Abstracts
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
"Cell Fate Decisions are Controlled by Lysosomal Rewiring of Nutrient Utilization"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
"The Role of Wnt/STOP in Drug-Resistant Cancer Cells"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure