1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: A Fresh Perspective on Atherosclerosis - The Role of Complement
Redouane Aherrahrou (University of Virginia/University of Luebeck/University of Eastern Finland, Germany)
3:15 pm - 3:25 pm
3:25 pm - 3:50 pm
Claudia Kemper (National Institutes of Health, United States) "Complement and Complosome - An Old Dog Still Bites"
3:50 pm - 4:00 pm
4:00 pm - 5:30 pm
5:30 pm - 7:30 pm
Molecular Mechanisms of Cardiometabolic Disease
Sabrina Robichaud (University of Ottawa Heart Institute, Canada) and Tarik Zahr (Columbia University, United States)
5:30 pm - 5:45 pm
Johannes Gollmer (Medical University Graz, Austria) "Molecular Alterations of Human Diabetic Heart Disease Revealed using Single Nucleus Sequencing"
5:45 pm - 5:50 pm
5:50 pm - 6:05 pm
Tom Collins (Baker Heart and Diabetes Institute, Australia) "Exploring How Cardiometabolic Disease Impacts the Immune Cell Lipidome"
6:05 pm - 6:10 pm
6:10 pm - 6:25 pm
Teresa Gerhardt (Icahn School of Medicine at Mount Sinai, United States) "Coronary Culprit Plaque Morphology Determines Residual Inflammatory Risk and Outcome – Novel Aspects Towards Precision Prevention Following Acute Coronary Syndrome"
6:25 pm - 6:30 pm
6:30 pm - 6:45 pm
Rachel Carley (Brown University, United States) "Rac1 and NF-kB Signaling Regulate Macrophage Expression of IL-1ß and Atherosclerotic Calcification: Implications for Targeted Therapies"
6:45 pm - 6:50 pm
6:50 pm - 7:05 pm
Megan Mulholland (Lund University, Sweden) "IL1RAP Blockade Limits Development of Atherosclerosis and Reduces Plaque Inflammation"
7:05 pm - 7:10 pm
7:10 pm - 7:25 pm
Gage Stuttgen (Medical College of Wisconsin, United States) "FFAR4 Regulates Macrophage Metabolism and Foam Cell Formation"
7:25 pm - 7:30 pm
8:00 pm - 9:00 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Cells of the Vessel Wall and Metabolic Determinants of Cardiovascular Disease
Kelsey Jarrett (UCLA, United States) and Corey Scipione (University Health Network, Canada)
9:00 am - 9:15 am
Tamara Vico (University Heart Center Freiburg-Bad Krozingen, Germany) "Recruited and Resident Cardiac Macrophage Phenotypes Converge in the Healing Infarct but not in the Failing Heart Exposed to Continuous Pressure Overload"
9:15 am - 9:20 am
9:20 am - 9:35 am
Allen Chung (Columbia University, United States) "The Matrix Metalloproteinase ADAMTS7 Increases Foam Cell Formation and Atherosclerosis"
9:35 am - 9:40 am
9:40 am - 9:55 am
Sneha Raju (University of Toronto , Canada) "Endothelial Cells Communicate with Surrounding Vascular Cells via Bidirectional and Polarized Secretion of Extracellular Vesicular Cargo: Implications for Atherosclerotic Plaque Development"
9:55 am - 10:00 am
10:00 am - 10:15 am
Jared Elenbaas (Washington University in St. Louis, United States) "The Cardiometabolic Disease Risk Protein SVEP1 Signals Through the Orphan Receptor PEAR1"
10:15 am - 10:20 am
10:20 am - 10:35 am
Rosalie W.M. Kempkes (Amsterdam UMC, The Netherlands) "EZH2 Inhibition Reduces Macrophage Inflammatory Responses in Atherosclerosis"
10:35 am - 10:40 am
10:40 am - 10:55 am
Yasemin Zurke (University of Oxford, United Kingdom) "Macrophage Heterogeneity in Metabolic Disease"
10:55 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Mentorship Component: Insights Into Successfully Obtaining Grants
Mabruka Alfaidi (LSU Health – Shreveport, United States)
1:30 pm - 1:55 pm
Michelle Olive (National Heart, Lung, and Blood Institute, NIH, United States) "Navigating the NIH Career Development Awards"
1:55 pm - 2:00 pm
2:00 pm - 2:25 pm
Andrew Murphy (Baker Heart and Diabetes Institute, Australia) "High Dietary Salt Promotes a TH
17 Cell Driven Gut-Bone Axis to Regulate Haematopoiesis and Atherosclerosis"
2:25 pm - 2:30 pm
2:30 pm - 3:00 pm
Complete the GRS Evaluation Forms; Election of Future Chair(s)