Sunday
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2:00 pm - 9:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
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7:40 pm - 9:30 pm |
Models of Basal Ganglia and Learning
Discussion Leader: Ann Graybiel (Massachusetts Institute of Technology, United States)
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7:40 pm - 8:00 pm |
Introduction by Discussion Leader
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8:00 pm - 8:20 pm |
Patricia Janak (Johns Hopkins University, United States)
"Ventral Tegmental Area Dopamine and Acquisition of State Values"
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8:20 pm - 8:35 pm |
Discussion
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8:35 pm - 8:55 pm |
Michale Fee (Massachusetts Institute of Technology, United States)
"Connectomic Test of a Hypothesis for Songbird Basal Ganglia Function"
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8:55 pm - 9:10 pm |
Discussion
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9:10 pm - 9:30 pm |
General Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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8:30 am - 9:00 am |
Group Photo
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9:00 am - 12:30 pm |
Functional Heterogeneity of Basal Ganglia Projection Circuits and Dopaminergic Inputs
Discussion Leader: Anatol Kreitzer (Gladstone Institutes, United States)
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9:00 am - 9:20 am |
Talia Lerner (Northwestern University, United States)
"Dopamine Circuits Controlling the Onset of Compulsive Reward-Seeking"
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9:20 am - 9:30 am |
Discussion
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9:30 am - 9:50 am |
Ana Rodrigues (University of Minho, Portugal)
"Role of Nucleus Accumbens Subcircuits in Reward and Aversion"
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9:50 am - 10:00 am |
Discussion
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10:00 am - 10:20 am |
Adam Carter (New York University, United States)
"Cholinergic Interneurons in the Nucleus Accumbens"
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10:20 am - 10:30 am |
Discussion
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10:30 am - 11:00 am |
Coffee Break
|
11:00 am - 11:20 am |
Vanessa Ruta (The Rockefeller University/HHMI, United States)
"Neuromodulatory Mechanisms of Learning and Memory in Drosophila"
|
11:20 am - 11:30 am |
Discussion
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11:30 am - 11:50 am |
Rajeshwar Awatramani (Northwestern University, United States)
"Development and Diversity of Midbrain Dopamine Neurons"
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11:50 am - 12:00 pm |
Discussion
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12:00 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
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3:00 pm - 4:00 pm |
The GRC Power Hour™
The GRC Power Hour™ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
Organizers: Ilana Witten (Princeton University, United States) and Zayd Khaliq (National Institute of Neurological Disorders and Stroke, NIH, United States)
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4:00 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Modulating the Modulators
Discussion Leader: Nicolas Tritsch (NYU School of Medicine, United States)
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7:30 pm - 7:50 pm |
Stephanie Cragg (University of Oxford, United Kingdom)
"Axonal Gating of Striatal Dopamine Transmission"
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7:50 pm - 8:00 pm |
Discussion
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8:00 pm - 8:20 pm |
Stephen Rayport (Columbia University, United States)
"The Dopamine Neuron Synaptic Map"
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8:20 pm - 8:30 pm |
Discussion
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8:30 pm - 8:50 pm |
Christopher Ford (University of Colorado, United States)
"Dopamine Transmission in Striatal Circuits"
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8:50 pm - 9:00 pm |
Discussion
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9:00 pm - 9:20 pm |
Pascal Kaeser (Harvard Medical School, United States)
"Mechanisms and Roles of Fast Dopamine Signaling"
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9:20 pm - 9:30 pm |
Discussion
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Tuesday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Basal Ganglia in Health and Disease
Discussion Leader: Mary Kay Lobo (University of Maryland School of Medicine, United States)
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9:00 am - 9:20 am |
Raffaella Tonini (Istituto Italiano di Tecnologia (IIT), Italy)
"Spatial Reorganization of Striatal Signaling Complexes in Behavioral Flexibility "
|
9:20 am - 9:30 am |
Discussion
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9:30 am - 9:50 am |
Alexandra Nelson (University of California, San Francisco, United States)
"Dopamine and the Striatal Microcircuit Dysfunction in Dyskinesias"
|
9:50 am - 10:00 am |
Discussion
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10:00 am - 10:20 am |
X. William Yang (University of California, Los Angeles, United States)
"Understanding the Role of Uninterrupted CAG Repeats in Striatum-Selective Pathogenesis in Huntington’s Disease"
|
10:20 am - 10:30 am |
Discussion
|
10:30 am - 11:00 am |
Coffee Break
|
11:00 am - 11:20 am |
Christian Luscher (University of Geneva, Switzerland)
"Cell-Type-Specific Synaptic Plasticity in the Dorsal Striatum Underlying Compulsive Cocaine Use"
|
11:20 am - 11:30 am |
Discussion
|
11:30 am - 11:50 am |
Meaghan Creed (Washington University School of Medicine, United States)
"Dissecting the Role of Non-Canonical Ventral Pallidal Populations in Reward Processing"
|
11:50 am - 12:00 pm |
Discussion
|
12:00 pm - 12:20 pm |
Robert Edwards (University of California, San Francisco, United States)
"Different Modes of Neurotransmitter Release"
|
12:20 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Motivating Movement
Discussion Leader: Alexandra Nelson (University of California, San Francisco, United States)
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7:30 pm - 7:50 pm |
Paola Ortelli (Hospital of Vipiteno (SABES-ASDAA), Italy)
"When and How Cognition and Motivation Freeze Motor Behavior in Parkinson’s Disease"
|
7:50 pm - 8:00 pm |
Discussion
|
8:00 pm - 8:20 pm |
Sandeep Robert Datta (Harvard Medical School, United States)
"Probing Corticostriatal Function Through Motion Sequencing"
|
8:20 pm - 8:30 pm |
Discussion
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8:30 pm - 8:50 pm |
Marc Fuccillo (University of Pennsylvania, United States)
"Distributed Processing for Action Control by Prelimbic Circuits Targeting the Anterior-Posterior Dorsal Striatal Axis"
|
8:50 pm - 9:00 pm |
Discussion
|
9:00 pm - 9:20 pm |
Joshua Berke (University of California, San Francisco, United States)
"Dopamine and the Invigoration of Behavior"
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9:20 pm - 9:30 pm |
Discussion
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Wednesday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
From Cells and Circuits to Motivated Behavior
Discussion Leader: Talia Lerner (Northwestern University, United States)
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9:00 am - 9:20 am |
Veronica Alvarez (National Institutes of Health, United States)
"Suppression of Cortical Evoked Dopamine by Drugs of Abuse Potentiates Reward-Coding Dopamine Signals in the Striatum"
|
9:20 am - 9:30 am |
Discussion
|
9:30 am - 9:50 am |
Mark Schnitzer (Stanford University and Howard Hughes Medical Institute, United States)
"Functional Organization of Striatal Dynamics in Health and Disease"
|
9:50 am - 10:00 am |
Discussion
|
10:00 am - 10:10 am |
Lauren McElvain (University of California, San Diego, United States)
"Specificity of Basal Ganglia Output Modules"
|
10:10 am - 10:15 am |
Discussion
|
10:15 am - 10:25 am |
Nicholas Foster (University of California Los Angeles, United States)
"The Cortico-Basal Ganglia-Thalamic Network"
|
10:25 am - 10:30 am |
Discussion
|
10:30 am - 11:00 am |
Coffee Break
|
11:00 am - 11:20 am |
Carrie Ferrario (University of Michigan, United States)
"Roles for Striatal Plasticity in Obesity"
|
11:20 am - 11:30 am |
Discussion
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11:30 am - 11:50 am |
Alexxai Kravitz (Washington University in St. Louis, United States)
"Basal Ganglia Adaptations in Mice Following Obesity and Weight Loss"
|
11:50 am - 12:00 pm |
Discussion
|
12:00 pm - 12:20 pm |
Dayu Lin (NYULMC, United States)
"Dopamine and Social Behaviors"
|
12:20 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Dialogue Between Models of Basal Ganglia Function and Experimental Data
Discussion Leader: Carmen Canavier (LSU Health Sciences Center New Orleans, United States)
|
7:30 pm - 7:55 pm |
Vikram Gadagkar (Columbia University, United States)
"Dopamine Neurons Evaluate Natural Fluctuations in Performance Quality"
|
7:55 pm - 8:00 pm |
Discussion
|
8:00 pm - 8:25 pm |
Naoshige Uchida (Harvard University, United States)
"The Diversity of Dopamine Neurons: A Normative Perspective"
|
8:25 pm - 8:30 pm |
Discussion
|
8:30 pm - 8:40 pm |
Maxime Assous (Center for Molecular and Behavioral Neuroscience, Rutgers University, United States)
"Organization of Extrinsic Inhibitory Inputs to Striatal Circuits"
|
8:40 pm - 8:45 pm |
Discussion
|
8:45 pm - 8:55 pm |
Megha Kori (NYU Langone Grossman School of Medicine, United States)
"Cell-Type Specific Auditory Responses and Connectivity in the Posterior Striatum"
|
8:55 pm - 9:00 pm |
Discussion
|
9:00 pm - 9:10 pm |
Carla Golden (New York University, United States)
"Hormonal Regulation of Dopaminergic Signaling and Value-Based Decision-Making"
|
9:10 pm - 9:15 pm |
Discussion
|
9:15 pm - 9:25 pm |
Jose Lanciego (Foundation for Applied Medical Research (FIMA) University of Navarra, Spain)
"Blaming Neuromelanin for Parkinson's Disease:Ttime-Dependent Tyrosinase Overexpression Drives Endogenous Synucleinopathy in Nonhuman Primates"
|
9:25 pm - 9:30 pm |
Discussion
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Thursday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Insights into Molecular and Cellular Mechanisms from New Tools and Novel Approaches
Discussion Leader: Veronica Alvarez (National Institutes of Health, United States)
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9:00 am - 9:20 am |
Nicolas Tritsch (NYU School of Medicine, United States)
"What Neuromodulatory Soup? Striatal Acetylcholine and Dopamine Levels Show Persistent Coordinated Oscillations In Vivo"
|
9:20 am - 9:30 am |
Discussion
|
9:30 am - 9:50 am |
Suk Joon Lee (Harvard Medical School, United States)
"Dopamine Dependent PKA Dynamics in the Nucleus Accumbens during Reward Based Learning"
|
9:50 am - 10:00 am |
Discussion
|
10:00 am - 10:20 am |
David Sulzer (Columbia University, United States)
"Sound and Language Learning in Basal Ganglia Synapses"
|
10:20 am - 10:30 am |
Discussion
|
10:30 am - 11:00 am |
Coffee Break
|
11:00 am - 11:20 am |
Laurent Venance (Collège de France, France)
"Region- and Input-Specific Striatal Plasticity Consistent with Distinct Memory Abilities During Procedural Learning"
|
11:20 am - 11:30 am |
Discussion
|
11:30 am - 11:40 am |
Kimberly Reinhold (Harvard Medical School, United States)
"Timescale of Posterior Dorsomedial Striatum’s Contribution to Trial and Error Learning"
|
11:40 am - 11:45 am |
Discussion
|
11:45 am - 11:55 am |
Scott Owen (Stanford University, United States)
"Cross-Species Comparison Reveals Primate-Specific Physiology in Putamen Cell-Types"
|
11:55 am - 12:00 pm |
Discussion
|
12:00 pm - 12:20 pm |
Nicole Calakos (Duke University Medical Center, United States)
"SPOTlight on a Hidden Regulator of Neuromodulation and Motor Learning: Protein Synthesis by the “Integrated Stress Response” ISR"
|
12:20 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Basal Ganglia and Extended Circuits in Cognition and Decision-Making
Discussion Leaders: Zayd Khaliq (National Institute of Neurological Disorders and Stroke, NIH, United States) and Ilana Witten (Princeton University, United States)
|
7:30 pm - 7:50 pm |
Richard Krauzlis (National Eye Institute, NIH, United States)
"Visual Decisions in Monkeys and Mice"
|
7:50 pm - 8:00 pm |
Discussion
|
8:00 pm - 8:20 pm |
Arif Hamid (University of Minnesota, United States)
"Dopamine Waves as a Circuit Mechanism for Spatiotemporal Credit Assignment"
|
8:20 pm - 8:30 pm |
Discussion
|
8:30 pm - 8:50 pm |
Okihide Hikosaka (National Eye Institute, NIH, United States)
"Short and Long Memory Mechanisms in Basal Ganglia to Control Goal-Directed Behaviors in Various Environments"
|
8:50 pm - 9:00 pm |
Discussion
|
9:00 pm - 9:20 pm |
General Discussion
|
9:20 pm - 9:30 pm |
Closing Remarks
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Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
|