|2:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||Keynote Session|
|3:45 pm - 4:15 pm ||Cynthia Kenyon (University of California, San Francisco, USA)
"Genes that affect aging in C. elegans"
|4:15 pm - 4:30 pm ||Discussion|
|4:30 pm - 6:00 pm||Poster Session I (presenters with last names A-M)|
|7:30 pm - 9:30 pm||Metabolism and Aging|
|Discussion Leaders: Mark McCormick (The Buck Institute for Research on Aging, USA) and Dario Valenzano (Stanford University School of Medicine, USA)|
|7:30 pm - 7:45 pm ||Kathleen Fischer (Barshop Institute for Longevity and Aging Studies, USA)|
"Effects of rapamycin administered late in life on healthspan in C57BL/6NIA Mice"
|7:45 pm - 7:50 pm ||Discussion|
|7:50 pm - 8:05 pm ||James Flynn (The Buck Institute for Research on Aging, USA)
"Longitudinal Aging Studies of the Cardiovascular and Metabolic effects of Rapamycin in C57Bl6 mice"
|8:05 pm - 8:10 pm ||Discussion|
|8:10 pm - 8:25 pm ||Sarah Mitchell (National Institute on Aging, USA)|
"SRT2104, a molecule designed to activate SIRT1, extends lifespan and healthspan of C57BL6/J mice"
|8:25 pm - 8:30 pm ||Discussion|
|8:30 pm - 8:45 pm ||Marcelo Mori (Federal University of Sao Paulo, Brasil)|
"microRNA Processing in Adipose Tissue: Role in Metabolism and Age-Related Diseases"
|8:45 pm - 8:50 pm ||Discussion|
|8:50 pm - 9:05 pm ||Samantha Solon (ANZAC Research Institute and the University of Sydney, AU)|
"Macronutrient regulation, metabolism and aging in mice"
|9:05 pm - 9:10 pm ||Discussion|
|9:10 pm - 9:25 pm ||Di Chen (The Buck Institute for Research on Aging, USA)|
"Synergistic lifespan extension by daf-2 rsks-1 in C. elegans"
|9:25 pm - 9:30 pm ||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Role of Cell Signaling and Aging|
|Discussion Leaders: Marc Lucanic (The Buck Institute for Research on Aging, USA) and William Ja (The Scripps Research Institute, USA)|
|9:00 am - 9:15 am ||Clara Correia-Melo (Institute for Ageing and Health Newcastle University, UK)|
"The Senescence-associated Secretory Phenotype stabilizes Cellular Senescence via mitochondrial dysfunction and ROS generation"
|9:15 am - 9:20 am ||Discussion|
|9:20 am - 9:35 am ||Remi-Martin Laberge (The Buck Institute for Research on Aging, USA)|
"mTOR-Dependent IL-1a Translation Controls the Senescence-Associated Secretory Phenotype"
|9:35 am - 9:40 am ||Discussion|
|9:40 am - 9:55 am ||Brett Robison (University of California, Berkeley and The Buck Institute for Research on Aging, USA)
"Proteasome abundance modulates yeast replicative lifespan"
|9:55 am - 10:00 am ||Discussion|
|10:00 am - 10:15 am ||Rebecca Taylor (The Salk Institute for Biological Studies, USA)|
"The UPR is a cell non-autonomous regulator of stress resistance and aging"
|10:15 am - 10:20 am ||Discussion|
|11:00 am - 12:30 pm||Poster Session II (presenters with last names N-Z)|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Career Perspectives: Academic vs. Industry|
|Discussion Leaders: Gordon Lithgow (The Buck Institute for Research on Aging, USA), Bita Nakhai (National Institute on Aging, USA) and Avirup Bose (Novartis Institutes for BioMedical Research, Inc., USA)|
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill out GRS Evaluation Forms|
|3:00 pm||Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.|