1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Development of Geroprotectors for the Prevention of Frailty
Morten Scheibye-Knudsen (University of Copenhagen, Denmark)
3:15 pm - 3:45 pm
Ilaria Bellantuono (University of Sheffield, United Kingdom) "The Development of Geroprotectors for the Prevention of Frailty"
3:45 pm - 3:50 pm
3:50 pm - 4:00 pm
4:00 pm - 5:30 pm
5:30 pm - 7:30 pm
Molecular Aging to Functional Aging in the Era of Data Science
Dennis de Bakker (FLI Jena, Germany)
5:30 pm - 5:40 pm
Mara Neuerburg (Max Planck Institute for Biology of Ageing, Germany) "
in vitro Functional Characterization of Rare Genetic Variants Identified in Exceptionally Long-Lived Individuals"
5:40 pm - 5:45 pm
5:45 pm - 5:55 pm
Jasmin Revanna (University of California, San Diego, United States) "Microglia Derived From ApoE4 iPSCs Have Alzheimer’s Disease Related Molecular Defects"
5:55 pm - 6:00 pm
6:00 pm - 6:10 pm
Nelly Olova (University of Edinburgh, United Kingdom) "Accelerated Epigenetic Ageing in Patients With Type I Interferonopathies"
6:10 pm - 6:15 pm
6:15 pm - 6:25 pm
Alan Tomusiak (Buck Institute for Research on Aging, United States) "Development of a Novel Epigenetic Clock Resistant to Changes in Immune Cell Composition"
6:25 pm - 6:30 pm
6:30 pm - 6:40 pm
Lucy Xu (Stanford University, United States) "Single-Cell Transcriptomics Reveals Restoration of Neuronal Progenitors in the Old Neurogenic Niche by Partial Reprogramming"
6:40 pm - 6:45 pm
6:45 pm - 6:55 pm
Jingxun Chen (Stanford University - Stanford, CA, United States) "A Short-Lived Killifish Model for Studying the Interaction Between Aging and Reproduction"
6:55 pm - 7:00 pm
7:00 pm - 7:10 pm
Viktoria Wagner (Saarland University, Germany) "Aging miRNA Expression Atlas of All Major Organs in Mouse"
7:10 pm - 7:15 pm
7:15 pm - 7:25 pm
Jesse Poganik (Brigham and Women's Hospital, Harvard Medical School, United States) "Biological Age is Increased by Stress and Restored Upon Recovery"
7:25 pm - 7:30 pm
8:00 pm - 9:00 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Interventions to Promote Healthy Aging
Jesus Gil (MRC LMS/imperial College London, United Kingdom)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:25 am
Eleanor Phillips (University of Sheffield, United Kingdom) "Rapamycin Not Dietary Restriction Improves Resilience Against Pathogens"
9:25 am - 9:30 am
9:30 am - 9:40 am
Raul Castro (University of Arizona, United States) "Targeting the Kynurenine Pathway to Induce a Hormetic Response Mediated by Reactive Oxygen Species (ROS)"
9:40 am - 9:45 am
9:45 am - 9:55 am
Utkarsh Tripathi (Mayo Clinic, United States) "A Subset of Senescent Cells With a Tissue-Damaging Phenotype Is Susceptible to Elimination by Senolytics"
9:55 am - 10:00 am
10:00 am - 10:10 am
Brian Lananna (Washington University in St. Louis, United States) "eNAMPT-Containing Extracellular Vesicles Mitigate Age-Related Cognitive Decline"
10:10 am - 10:15 am
10:15 am - 10:25 am
Alina Ryabova (Leibniz Institute on Aging - Fritz Lipmann Institute, Germany) "Food-Gut-Stool Interplay of the Commensal Bacterial Community in Killifish"
10:25 am - 10:30 am
10:30 am - 10:40 am
Maarouf Baghdadi (Max Planck Institute for Biology of Ageing, Germany) "Intermittent Rapamycin Feeding Reduces Adverse Effects on Metabolic Health While Maintaining Lifespan Extension in Male and Female Mice"
10:40 am - 10:45 am
10:45 am - 10:55 am
Chiara Herzog (Universität Innsbruck, Austria) "Quantifying the Impact of Intermittent Fasting on Multiomic Biomarkers of Aging in a Systems Approach: Preliminary Results From a Longitudinal Lifestyle Intervention Trial"
10:55 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Mentorship Component: Aging as a Career
Juan Vazquez (Sudmant Lab, University of California - Berkeley, United States)
1:30 pm - 1:40 pm
Introduction by Discussion Leader
1:40 pm - 2:30 pm
Aging as a Career
Bita Nakhai (National Institute on Aging, NIH, United States)
Anna Kriebs (Nature Aging, Germany)
Ethan Sarnoski (Cambrian Bio, United States)
2:30 pm - 3:00 pm
Complete the GRS Evaluation Forms; Election of Future Chair(s)