Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: CAZymes from Terrestrial and Aquatic Ecosystems
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:20 pm
"Mining Microbiomes for Nature's CAZymes"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:05 pm
"Functional Exploration of the CAZy Databank and Beyond: Discovery of New Families and Substrate Specificities"
9:05 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Plant Cell Walls and Implications to Their Bioconversion
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"The Importance of Precise Substitution Patterns for Interactions of Hemicelluloses with Cellulose Fibrils"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Sugars from the Sea: Cell Wall Polysaccharides from Macroalgae"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Functional Analysis of Polygalacturonases During Water-Conducting Cell Formation Required for Plant Adaptation to Land"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"The Remarkable Wall-Loosening Actions of a Maize β-Expansin"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Visualizing Polysaccharide Uptake Using Fluorescent Glycan Conjugates and Single Cell Microscopy"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Enzyme Action on Intermolecular Linkages and Complex Carbohydrate Structures
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Elucidating the Action of Glucuronoyl Esterases: From Model Substrates to Action on Lignin Carbohydrate Complexes"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Systems Biology Approaches to Characterize Bacterial Chitinases: A Microbe-Centric Perspective on the Degradation of Complex Insoluble Substrates"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:10 pm
"Divide and Conquer: Using Subfamily Analysis to Refine Specificity Determination and Prediction in GH16"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Carbohydrate Active Enzyme Cascades from Diverse Habitats
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Solving the Puzzle of Anaerobic Biomass Degradation: Metatranscriptomics of Rumen Fungi"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Where the Wild Things Are: CAZyme Lessons Learnt from Wild and Domestic Herbivores"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"The Critical Roles of Sulfatases and Fucosidases in Mucin Utilization by Bacteroides"
11:05 am - 11:10 am
Discussion
11:10 am - 11:35 am
"Expanding the Notion of Polysaccharide Utilization Loci: Carrageenan Catabolism in Marine Heterotrophic Bacteria"
11:35 am - 11:45 am
Discussion
11:45 am - 12:10 pm
"Exploring the Marine Glyco-Carbon Cycle with CAZymes"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Multi-Enzyme Complexes in Nature and by Design
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Ancestral Enzymes: Towards Highly Efficient Biomass Conversion"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Seaweedosome: Engineering of an Efficient Agarose-Degrading Multi-Enzyme Complex"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"VersaTile: A High-Throughput DNA Assembly Method for the Combinatorial Construction and Evaluation of Cellulosome Components"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Oxidative Enzymes and Their Partners
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Connecting the Dots Between Oxidoreductases in Lignocellulose Conversion"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Discovery of Fungal Copper Proteins Evolutionarily Related to Lytic Polysaccharide Monooxygenases"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Activation of a Bacterial Lytic Polysaccharide Monooxygenase Using a Small C-Type Cytochrome"
11:10 am - 11:15 am
Discussion
11:15 am - 11:40 am
"Biophysical Studies of Cellulose Oxidation: Effects on Water and Enzyme Interactions with Cellulose Surfaces"
11:40 am - 11:50 am
Discussion
11:50 am - 12:15 pm
"Lytic Polysaccharide Monooxygenases in Preparation of Cellulosic Materials"
12:15 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Carbohydrate-Active Enzymes for New Bio-Based Chemicals and Materials
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Engineering of Glycosidases for Enzymatic Synthesis of Human Milk Oligosaccharides"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"New Cellulosic Materials via Cellulose Endo-Transglycosylases and Cellodextrin Phosphorylases"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Interplay Between Cellulose Defects, Nanomechanics and Cellulases: New Insights and Implications for Production of Nanocellulose"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emerging Tools for CAZyme Discovery, Design and Development
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Production Hosts for the Characterization of New Carbohydrate-Active Enzymes"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Unbiased Simulations of CAZy Reaction Mechanisms for Enzyme Engineering"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Redesigning N-Glycosylation Sites to Improve CAZyme Efficiency"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"Machine Learning in Enzyme and Biomaterial Design"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Selected Poster Presentations
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"The Effect of LPMOs and Endoglucanases on Cellulose Accessibility and Productive Enzyme Binding"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Roseburia intestinalis : A Primary Degrader of Dietary β-Mannans"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Breakdown and Utilization of Arabinogalactan by Bacteroides in the Human Gut"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"The Role of TonB in Polysaccharide Utilization by the Bacteroidetes"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
"Increasing the Digestibilty of Non-Starch Dietary Polysaccharides with CAZymes Bioprospected from the Chicken Intestinal Microbiome"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure