Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Pathway Engineering |
| Discussion Leader: Norihiko Misawa (Ishikawa Prefectural University, Japan) |
7:40 pm - 7:45 pm | Opening Remarks |
7:45 pm - 8:00 pm | Introduction by Discussion Leader |
8:00 pm - 8:20 pm | Paul Christou (Universitat de Lleida, Spain) "Field-Grown Engineered Maize Hybrids with
Diverse Carotenoid Profiles Reveal the Complex Interplay Between Synthetic and
Endogenous Metabolic Pathways" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Paul Fraser (Royal Holloway University of London, United Kingdom) "Engineering the Carotenoid Pathway in Solanaceae
for Renewable Sources of Nutritional and Industrial Carotenoids" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Ralf Welsch (University of Freiburg, Germany) "Novel Avenues for Controlling Carotenoid Homeostasis in Plant Tissues" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Carotenoid Biosynthesis |
| Discussion Leader: Barry Pogson (Australian National University, Australia) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Dean Dellapenna (Michigan State University, USA) "Insights into Carotenoid Accumulation from
Quantitative Genetics/Genomics Approaches" |
9:35 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Li Li (Agricultural Research Service, USDA / Cornell University, USA) "Dual Functions of OR in Regulating Carotenoid Biosynthesis and Chromoplast Biogenesis" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:15 am | Monica Schmidt (University of Arizona, USA) "Enhanced Accumulation of β-Carotene in Seeds of Both Soybean
and Camelina Result in Increased Levels of Seed Protein Content" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Manuel Rodriguez-Concepcion (Centre for Research in Agricultural Genomics (CRAG), Spain) "Control of Plant Carotenoid Biosynthesis by Light Signals" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Claudia Stange (University of Chile, Chile) "Abscisic Acid
and DcPSY2 Modulation During Salt Stress Tolerance in Daucus carota" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Carotenoids in Health and Disease |
| Discussion Leader: Helmut Sies (Heinrich Heine University Dusseldorf, Germany) |
6:00 pm - 6:15 pm | Introduction by Discussion Leader |
6:15 pm - 6:40 pm | George Lietz (Newcastle University, United Kingdom) "Characterisation of the Low Responder Phenotype" |
6:40 pm - 6:50 pm | Discussion |
6:50 pm - 7:15 pm | Sherry Tanumihardjo (University of Wisconsin-Madison, USA) "Vitamin A Liver Status Influences Provitamin A Bioconversion to Retinol and Tissue Accumulation of Carotenoids" |
7:15 pm - 7:25 pm | Discussion |
7:25 pm - 7:50 pm | Nancy Moran (Ohio State University Wexner Medical Center, USA) "Gene-Tomato Carotenoid Interactions Impacting Carotenoid Biodistribution and Anti-Cancer Activity" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Apocarotenoid
Synthesis and Functions |
| Discussion Leader: Salim Al-Babili (King Abdullah University of Science and Technology, Saudi Arabia) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Harro Bouwmeester (Wageningen University, The Netherlands) "Biosynthesis, Structural Diversity and Biological Function of Strigolactones" |
9:35 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Earl Harrison (Ohio State University, USA) "Substrate Specificity and Mechanism of Vertebrate Carotenoid Cleavage Oxygenases" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:25 am | Philip Kiser (Case Western Reserve University, USA) "Biophysical Characterization of the Non-Heme Iron Center of Carotenoid Cleavage Oxygenases" |
11:25 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Maria Jesus-Rodrigo (Institute of Agrochemistry and Food Technology (IATA-CSIC), Spain) "Coloration Diversity in Citrus Fruits: Determining the Role of Carotenoid Cleavage Oxygenases" |
12:05 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Carotenoids and Disease
Prevention |
| Discussion Leader: Jose Canas (Nemours Children's Health System, USA) |
6:00 pm - 6:10 pm | Introduction by Discussion Leader |
6:10 pm - 6:35 pm | Yoav Sharoni (Ben-Gurion University, Israel) "Carotenoids and Their Derivatives Synergize with Other Phytonutrients to Produce Enhanced Anti-Cancer and Anti-Inflammatory Effects" |
6:35 pm - 6:45 pm | Discussion |
6:45 pm - 7:00 pm | Ivan Petyaev (Lycotec, United Kingdom) "Lycopene and Lutein Clinical and Nutritional Challenges" |
7:00 pm - 7:05 pm | Discussion |
7:05 pm - 7:30 pm | Elizabeth Johnson (Tufts University, USA) "The Role of Lutein in Cognitive Function: Mechanisms of Action" |
7:30 pm - 7:40 pm | Discussion |
7:40 pm - 7:55 pm | Antonio Melendez-Martinez (Universidad de Sevilla, Spain) "The Colorless Carotenoid Phytoene and Phytofluene: From Chemistry to Health-Promoting Biological Actions" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Photosynthesis and
Plastids |
| Discussion Leader: Krishna Niyogi (HHMI / University of California, Berkeley / Lawrence Berkeley National Laboratory, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Roberto Bassi (University of Verona, Italy) "Functions of Xanthophylls in Regulating Photosynthetic Light Use Efficiency" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Cheryl Kerfeld (Michigan State University / Lawrence Berkeley National Laboratory, USA) "Red Carotenoid Proteins – Structure, Diversity, and Evolution of an Expanded Family of Soluble Carotenoid Binding Proteins in Cyanobacteria" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:05 am | Manuel Llansola-Portoles (University of Paris-Saclay, France) "Triplet Formation Mechanism in Natural and Artificial Lycopene Aggregates" |
11:05 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Ralph Bock (Max-Planck-Institute of Molecular Plant Physiology, Germany) "Engineering Isoprenoid Metabolism in Plastid" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Diana Kirilovsky (Institute of Integrative Biology of the Cell (I2BC), Université Paris Saclay, France) "Distinct Activities of the Homologs of the N-Terminal Domain of the OCP" |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Apocarotenoid
Metabolism |
| Discussion Leader: Loredana Quadro (Rutgers University, USA) |
6:00 pm - 6:15 pm | Introduction by Discussion Leader |
6:15 pm - 6:40 pm | Alexander Moise (University of Kansas, USA) "DHRS3 and Its Role in the Metabolism of Apocarotenoids" |
6:40 pm - 6:50 pm | Discussion |
6:50 pm - 7:15 pm | Xiang-Dong Wang (Tufts University, USA) "Differential Mechanisms of Action of Apocarotenoids and Carotenoids" |
7:15 pm - 7:25 pm | Discussion |
7:25 pm - 7:50 pm | Olivia Costantina Demurtas (ENEA Casaccia Research Centre, Italy) "Crocin Biosynthesis in Saffron Stigmas: A Tale of Three Compartments" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Thursday |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
9:00 am - 12:30 pm | Carotenoids in Vision |
| Discussion Leader: John Landrum (Florida International University, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Paul Bernstein (University of Utah, USA) "Biosynthesis of Meso-Zeaxanthin" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | John Nolan (Waterford Institute of Technology, Ireland) "Enrichment of Macular Pigment Enhances Visual Performance and Cognitive Function in Subjects Free of Retinal Disease: The Central Retinal Enrichment Supplementation Trials (CREST)" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:05 am | Trevor McGill (Oregon Health and Science University, USA) "The Role of Xanthophylls and Omega-3 Fatty Acids in Retinal Aging and Macular Disease: Insights from a Monkey Model" |
11:05 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Darwin Babino (Case Western Reserve University, USA) "Carotenoid Cleavage Oxygenases in Animal Vision" |
11:35 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Joseph Corbo (Washington University School of Medicine in St. Louis, USA) "The Mechanistic Basis of Seeing Red and Being Red" |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Regulation of the Carotenoid Biosynthetic Pathway |
| Discussion Leader: Joseph Hirschberg (Hebrew University of Jerusalem, Israel) |
6:00 pm - 6:15 pm | Introduction by Discussion Leader |
6:15 pm - 6:40 pm | Eleanore Wurtzel (Lehman College, City University of New York, USA) "A Novel Gate-Keeper of Carotenoid Biosynthesis in Plants" |
6:40 pm - 6:50 pm | Discussion |
6:50 pm - 7:15 pm | Patricia Leon-Mejia (Instituto de Biotecnologia UNAM, Mexico) "The Role of Linear Carotenoids in the Leaf Development" |
7:15 pm - 7:25 pm | Discussion |
7:25 pm - 7:50 pm | Ryan McQuinn (Australian National University, Australia) "Exploiting Genetic Diversity for Characterization of Carotenoid Regulation in Tomato Fruit" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |