Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Chemokines: Insights from Structural and Functional Data
3:45 pm - 3:55 pm
"Nanoluciferase Complementation-Based Assay to Monitor β-Arrestin Recruitment to Chemokine Receptors"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"Structural Studies into Autoinhibition by CCL21"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Atypical Ligand Binding and Activation Modes of ACKR3"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chemokines in Homeostasis and Development
7:30 pm - 7:40 pm
"Engineering an Orthogonal Chemokine:GPCR System Using Rosetta"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Binding and Activation Variation Within the CCR1-2-5 Axis"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"A Molecular 'Clamp' Regulates Sdf1a and Sdf1a-Guided Cell Migration"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"CXCL12/SDF-1 Modulates the Rheological Properties of the Nucleus of Mouse Neutrophils"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"The Role of Heterotrimeric G Proteins in Homing and Migration of Lymph Derived T Cells"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Complement C5a Receptor Regulates CXCR2-Mediated Neutrophil Adhesion"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"COOH-Terminal SAA1 Peptides Fail to Induce Chemokines but Synergize with CXCL8 and CCL3 to Recruit Leukocytes via FPR2"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Homing of Activated, Lymph-Derived T Cells Involves a Mechanical 3D Sieve Barrier of the Subcapsular Sinus and Chemokine Receptors but Is Independent of Integrins and Selectins"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Chemokine Control of Immune Activation and Disease
9:00 am - 9:10 am
"Targeting Lymph Node Niches to Enhance Type 1 Immune Responses to Immunization"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Age-Related Systemic Inflammation Supports Aberrant Neutrophil Transendothelial Migration"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Identification of CXCL14-Responsive Cells in Healthy Peripheral Tissues"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"The Role of Dendritic Cells in the Dissemination of Mosquito-Transmitted Alphaviruses"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Dectin-2-Induced CCL2 Production in Cardiac Macrophages Ignites Vascular Inflammation in a Murine Model of Kawasaki Disease"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"CXCL14 Suppresses the Aggressive Phenotype in Triple Negative Breast Cancer (TNBC) Through CXCR4"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Drug-Induced Senescence Promotes Anti-Tumor Immunity via the Induction of CCL5"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Aeroallergen-Induced Central Memory CD4+ T Cells Induce Allergic Airway Inflammation Independently of Lung-Resident Memory"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Pathways
1:30 pm - 2:30 pm
Panel Discussion
Career Pathways
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
