Gordon Research Conferences
Conference Details

Gordon Research Conference

Conference Information



Initial Year





Meeting Cycle

24 Months

Conference Description

The Polyamine GRC is a multidisciplinary conference focused on the polyamine metabolic pathway. Polyamines are small organic polycations found in virtually all archaeal, eubacterial and eukaryotic cells. Polyamines are closely linked to cell growth, and inhibitors of polyamine biosynthesis have been investigated as anti-proliferative agents. Historically the Polyamine GRC centered around the study of the polyamine metabolic pathway as a target for chemotherapeutic intervention in cancer, covering the role of polyamines in mammalian cell proliferation and the related biochemistry, molecular biology, and organic chemistry. A central focus of the meetings was the effect of inhibition of polyamine biosynthesis on tumor development. In eukaryotic cells polyamines are highly regulated at the levels of transcription, translation and protein turnover, and much of the field has focused on investigating these mechanisms. The discovery that polyamine biosynthetic inhibitors are effective for the treatment of African Sleeping Sickness expanded the clinical role of polyamine biosynthetic inhibitors, and has led to interest in studying the pathway and its regulation in these protozoal pathogens. Despite their importance, we still do not fully understand the cellular function of polyamines, and much biology remains to be elucidated. A number of novel roles for polyamines have been found in different organisms, and the biosynthetic and catabolic pathways, as well as the mechanisms of regulation, are different throughout evolution.

What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.

Related Conference

This Gordon Research Conference (GRC) series is related to the "Polyamines" Gordon Research Seminar (GRS) series. Although a related GRS will typically be scheduled in conjunction with its parent GRC each time it meets, that may not always be the case. Refer to the individual meetings in the Meeting History section below for more details. For more information about the associated Gordon Research Seminar (GRS) series, click here.

What is a GRS? Gordon Research Seminars (GRS) are 2-day meetings that bring graduate students and post-docs together to discuss their cutting edge research among peers and mentors. Each GRS immediately precedes an associated Gordon Research Conference (GRC), and topics addressed at the GRS relate closely to the GRC.

Meeting History

YearMeeting NameDatesConference SiteChair(s)
2017 Polyamines
Polyamine Metabolism in Disease and Polyamine-Targeted Therapies
Jun 25-30 Waterville Valley Susan K. Gilmour
Alex R. Khomutov
2015 Polyamines
Polyamines and Their Metabolic Regulation in Biology and Disease
Jun 14-19 Waterville Valley Otto Phanstiel
Keiko Kashiwagi
2013 Polyamines
Regulation and Role of Polyamines in Biology and Disease
Jun 16-21 Waterville Valley John L. Cleveland
Chaim Kahana
2011 Polyamines Jun 19-24 Waterville Valley Lisa M. Shantz
Enzo Agostinelli
2009 Polyamines
Polyamine Genetics, Metabolism, Cellular Homeostasis and Drug Discovery
Jun 21-26 Waterville Valley Patrick M. Woster
Senya Matsufuji
2007 Polyamines Jun 17-22 Waterville Valley Margaret A. Phillips
Leena I. Alhonen
2005 Polyamines Jun 12-17 Connecticut College Eugene W. Gerner
Anthony J. Michael
2003 Polyamines Jun 15-20 Connecticut College Cyrus J. Bacchi
Lo Persson
2001 Polyamines Jun 24-29 Connecticut College Robert A. Casero
Heather M. Wallace
1999 Polyamines Aug 22-27 The Queen's College Philip Coffino
Kazuei Igarashi
1997 Polyamines Jun 8-13 New England College John L. Mitchell
Olli A. Janne
1995 Polyamines Jun 11-16 Kimball Union Academy Immo Scheffler
Alan H. Fairlamb
1993 Polyamines Jun 20-25 Colby-Sawyer College Olle Heby
Gordon D. Luk
1991 Polyamines Jun 17-21 Salve Regina University Carl W. Porter
Nikolaus Y. Seiler
1989 Polyamines Jun 19-23 Salve Regina University Peter P. McCann
Rowland H. Davies
1987 Polyamines Jul 6-10 Colby-Sawyer College Laurence J. Marton
1985 Polyamines Jul 1-5 Kimball Union Academy David R. Morris
1983 Polyamines Jul 11-15 Kimball Union Academy Anthony E. Pegg
1981 Chemistry and Biology of Polyamines Jun 29 - Jul 3 Kimball Union Academy Seymour S. Cohen
1979 Polyamines Jun 25-29 Proctor Academy Uriel Bachrach
1977 Polyamines Jun 13-17 Plymouth State College Werner K. Maas
1975 Polyamines Jun 23-27 Franklin Pierce University Diane H. Russell
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