Gordon Research Conferences
Conference Details

Proteolytic Enzymes and Their Inhibitors
Gordon Research Seminar

Conference Information



Initial Year





Meeting Cycle

24 Months

Conference Description

Proteases play key roles in virtually every aspect of cell biology and every function of multicellular organisms. They are essential in such fundamental cell processes as separation of chromosomes during mitosis, cell-cycle control, apoptosis, and signal transduction. At the organismal level, these enzymes control such processes as wound healing, antigen presentation, reproduction, and neo-vascularization. Disregulation of proteases leads to or exacerbates an array of human pathologies including arthritis, stroke, dementia, metabolic disorders, blood coagulation defects, and cardiomyopathy. And infectious agents utilize proteases to mount their attacks.

This Gordon Research Seminar was suggested at the 2010 Proteolytic Enzymes and their Inhibitors GRC meeting to provide an active forum for our younger scientists who were often enthusiastic observers despite the fact that they made up nearly one-quarter of our registrants. We intend to use the GRS as a platform to encourage our 'next generation' of protease biologists to become actively involved within the international community. The meeting will keep to the ideals of the related GRC and have talks/posters covering structure, function, physiological roles, developing techniques and synthetic inhibitors. The conference is attended by biochemists, synthetic chemists, crystallographers, kineticists, experts in mass spectrometry, investigators of new biological imaging techniques, biologists and protein chemists.

What is a GRS? Gordon Research Seminars (GRS) are 2-day meetings that bring graduate students and post-docs together to discuss their cutting edge research among peers and mentors. Each GRS immediately precedes an associated Gordon Research Conference (GRC), and topics addressed at the GRS relate closely to the GRC.

Related Conference

This Gordon Research Seminar (GRS) series is related to the "Proteolytic Enzymes and Their Inhibitors" Gordon Research Conference (GRC) series. Although a related GRS will typically be scheduled in conjunction with its parent GRC each time it meets, that may not always be the case. For more information about the associated Gordon Research Conference (GRC) series, click here.

What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.

Meeting History

YearMeeting NameDatesConference SiteChair(s)
2018 Proteolytic Enzymes and Their Inhibitors (GRS)
Exploring the Opportunities and Confronting the Challenges Surrounding Protease-Targeted Therapies
Jun 2-3 Renaissance Tuscany Il Ciocco Laura E. Edgington-Mitchell
Jaideep S. Dudani
2016 Proteolytic Enzymes and Their Inhibitors (GRS)
Understanding the Role of Proteolysis in Homeostasis and Disease
Jun 25-26 Renaissance Tuscany Il Ciocco Anthony J. O'Donoghue
Leila Akkari
2014 Proteolytic Enzymes and Their Inhibitors (GRS)
Proteases: Making the Cut in Biological Processes and Diseases
Jun 21-22 Renaissance Tuscany Il Ciocco Antoine H. Dufour
2012 Proteolytic Enzymes and Their Inhibitors (GRS) Jun 16-17 Renaissance Tuscany Il Ciocco Sheena McGowan
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