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Saturday
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| 1:00 pm - 5:00 pm |
Arrival and Check-in
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| 3:00 pm - 3:15 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
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| 3:15 pm - 4:00 pm |
Keynote Session: Regulation of Sphingolipid Metabolism
Discussion Leader: Elena-Raluca Nicoli (National Institutes of Health, USA)
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| 3:15 pm - 3:55 pm |
Tony Futerman (Weizmann Institute of Science, Israel)
"Why We Love Sphingolipids"
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| 3:55 pm - 4:00 pm |
Discussion
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| 4:00 pm - 5:30 pm |
Poster Session
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| 5:30 pm - 7:30 pm |
The Complex Biology of SLs and GSLs
Discussion Leader: Iris Zelnik (Weizmann Institute of Science, Israel)
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| 5:30 pm - 5:45 pm |
Denisa Jamecna (Biochemie Zentrum Heidelberg (BZH), Germany)
"STARD3 Transfers Sphingosine at Lysosome-ER Contact Sites"
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| 5:45 pm - 5:50 pm |
Discussion
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| 5:50 pm - 6:05 pm |
Henrik Nurmi (Åbo Akademi, Finland)
"In Vivo Effects of Glycolipid Transfer Protein (GLTP) Knockout in HeLa Cells"
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| 6:05 pm - 6:10 pm |
Discussion
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| 6:10 pm - 6:25 pm |
Bianca Esch (University of Osnabrück, Germany)
"Spatio-Temporal Control of Sphingolipid Metabolism in Saccharomyces Cerevisiae"
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| 6:25 pm - 6:30 pm |
Discussion
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| 6:30 pm - 6:45 pm |
Yuzhe Weng (University of Oxford, United Kingdom)
"Lipid-Mediated Inhibition of Niemann-Pick C1 Protein Contributes to the Pathogenesis of Pathogenic Mycobacteria"
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| 6:45 pm - 6:50 pm |
Discussion
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| 6:50 pm - 7:05 pm |
Tamir Dingjan (Weizmann Institute of Science, Israel)
"The Sphingoid Motif: Five Carbon Atoms That Do It All"
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| 7:05 pm - 7:10 pm |
Discussion
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| 7:10 pm - 7:25 pm |
Tasha Morrison (NIAMS/NIH, USA)
"Essential Role of Ugcg for Natural Killer Cell Development and Function"
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| 7:25 pm - 7:30 pm |
Discussion
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| 8:00 pm - 9:00 pm |
Dinner
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Sunday
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| 7:30 am - 8:30 am |
Breakfast
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| 9:00 am - 11:00 am |
When Things Go Wrong: Pathobiology of SLs and GSLs
Discussion Leader: Jason Weesner (St. Jude Children's Research Hospital, USA)
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| 9:00 am - 9:15 am |
Nivea Pereira de Sa (Stony Brook University, USA)
"Structure and Inhibition of Cryptococcus Neoformans Sterylglucosidase to Develop Antifungal Agents"
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| 9:15 am - 9:20 am |
Discussion
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| 9:20 am - 9:35 am |
Adam Majcher (University Hospital Zurich, Switzerland)
"Sphingosine-1-phosphate (S1P) Lyase Insufficiency Syndrome - SPLIS"
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| 9:35 am - 9:40 am |
Discussion
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| 9:40 am - 9:55 am |
Leobarda Robles-Martinez (University of Kentucky, USA)
"Hepatic Ceramide Accumulation During Fatty Liver Disease Requires Active Neutral Sphingomyelinase-2 and Drives Insulin Resistance"
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| 9:55 am - 10:00 am |
Discussion
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| 10:00 am - 10:15 am |
Tolulope Sokoya (University of Osnabrueck, Germany)
"Perturbation of Sphingomyelin Asymmetry, Cholesterol Organization and Lipid Order by Pathogenic SMS2 Variants"
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| 10:15 am - 10:20 am |
Discussion
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| 10:20 am - 10:35 am |
Maria Fazzari (University of Milano, Italy)
"GM1 Oligosaccharide Membrane Signalling: The Switch to Turn On a Neuroprotective Program Acting via Mitochondria Modulation"
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| 10:35 am - 10:40 am |
Discussion
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| 10:40 am - 10:55 am |
Leigh Fremuth (St. Jude Children's Research Hospital, USA)
"Investigating the Immunomodulatory Role of the Sialidase Neu1 During Neurodegeneration and Neuroinflammation"
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| 10:55 am - 11:00 am |
Discussion
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| 11:00 am - 12:30 pm |
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
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| 12:30 pm - 1:30 pm |
Lunch
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| 1:30 pm - 2:30 pm |
Mentorship Component: What Options Do I Have For My Scientific Career?
Discussion Leader: Janathan Juarez-Altuzar (Heidelberg University, Germany)
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| 1:30 pm - 2:30 pm |
Panel Discussion
What Options Do I Have For My Scientific Career?
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Timothy Cox (University of Cambridge, United Kingdom)
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Doris Höglinger (Heidelberg University Biochemistry Center, Germany)
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Frances Platt (University of Oxford, United Kingdom)
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Thomas Kirkegaard Jensen (Orphazyme A/S, Denmark)
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| 2:30 pm - 3:00 pm |
Evaluation Period
Fill in GRS Evaluation Forms
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| 3:00 pm |
Seminar Concludes
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