|1:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair: Zachary Dalebroux (University of Washington)|
|3:45 pm - 4:30 pm||Host-Pathogen Interactions|
|Discussion Leader: Aimee Richard (University of Pennsylvania)|
|3:45 pm - 4:15 pm ||Andrew Olive (Harvard Medical School)|
"Chlamydia trachomatis-mediated alterations in host protein stability are required for bacterial growth"
|4:15 pm - 4:30 pm ||Discussion|
|4:30 pm - 6:00 pm||Poster Session I: Toxin Action and the Host Response to Infection|
|7:30 pm - 9:30 pm||Mechanisms of Toxin Action|
|Discussion Leader: Francis Alonzo (NYU School of Medicine)|
|7:30 pm - 7:50 pm ||David Anderson (Medical College of Wisconsin)|
"ExoU and Ubiquitin: A Model System for Bacterial-Host Protein Interaction and Effector Folding"
|7:50 pm - 8:00 pm ||Discussion|
|8:00 pm - 8:20 pm ||Ladislav Bumba (Institute of Microbiology - Czech Republic)
"Structural basis for RTX protein folding upon secretion through the Type I secretion system"
|8:20 pm - 8:30 pm ||Discussion|
|8:30 pm - 8:50 pm ||Andrew McCluskey (Harvard Medical School)|
"Changing the receptor specificity of anthrax toxin"
|8:50 pm - 9:00 pm ||Discussion|
|9:00 pm - 9:20 pm ||Doris LaRock (University of Washington)|
"A Salmonella Typhimurium translocated glycerophospholipid: cholesterol acyltransferase promotes virulence by binding to the RhoA switch regions"
|9:20 pm - 9:30 pm ||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Immunity and the Host Response to Infection|
|Discussion Leader: Chris LaRock (University of Washington)|
|9:00 am - 9:20 am ||Dara Burdette (University of California-Berkeley)|
"A Mechanism for the Innate Immune Sensing of Cyclic Dinucleotides"
|9:20 am - 9:30 am ||Discussion|
|9:30 am - 9:50 am ||Lisa Maudsdotter (Stockholm University-Sweden)|
"Lactobacilli inhibit adherence of pathogenic bacteria to host cells by interfering with host cell calcium signaling"
|9:50 am - 10:00 am ||Discussion|
|10:00 am - 10:20 am ||Kerri-Lynn Sheahan (Tufts University)|
"Host Cell Contribution to Type III Secretion in Yersinia pseudotuberculosis"
|10:20 am - 10:30 am ||Discussion|
|10:30 am - 10:50 am ||Sarah Clark (University of Pennsylvania)|
"Phosphorylcholine allows for evasion of bactericidal antibody by Haemophilus influenzae"
|10:50 am - 11:00 am ||Discussion|
|11:00 am - 12:30 pm||Poster Session II: Virulence Mechanisms of Bacterial Pathogens|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:40 pm||Regulatory Mechanisms of Bacterial Pathogens|
|Discussion Leader: Edward Geisinger (Tufts University)|
|1:30 pm - 1:50 pm ||Jeffrey Mellin (CIRAD - France)
"A Cobalamin riboswitch regulates a long antisense RNA in Listeria monocytogenes"
|1:50 pm - 2:00 pm ||Discussion|
|2:00 pm - 2:20 pm ||Joseph Boll (University of Texas Southwestern)|
"Involvement of the Flagellar MS- and C-Rings in the Regulatory Cascade that Influences Flagellar Gene Expression in Campylobacter jejuni"
|2:20 pm - 2:30 pm ||Discussion|
|2:30 pm - 2:40 pm ||Concluding Remarks: Zachary Dalebroux (University of Washington) and Aimee Richard (University of Pennsylvania)|
|2:40 pm - 3:00 pm||Evaluation Period|
|Fill out GRS Evaluation Forms|
|3:00 pm||Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.|